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| Issue Date FY: 2025 ( Subtotal = $0 ) |
| 2025 | 2022 | HESPEROS, INC | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG071386 | Modulatory Role of Blood-Brain-Barrier and Enzymatic Activity in an Innovative Human Model of Cholinergic Drug Induced Dementia | 000 | 2 | NIH | 12/5/2024 | $0 |
|
| Issue Date FY: 2024 ( Subtotal = $1,000,000 ) |
| 2024 | 2024 | HESPEROS, INC | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | U44TR004811 | Human NeuromuscularJunction Platform to Evaluate Botulinum Toxin Potency | 000 | 1 | NIH | 4/23/2024 | $1,000,000 |
| 2024 | 2022 | HESPEROS, INC | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES032360 | Biodistribution and PK modeling of rat vs. human systems | 000 | 3 | NIH | 3/4/2024 | $0 |
| 2024 | 2022 | HESPEROS, INC | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG059511 | Human on a chip systems to investigate disease comorbidities common in the aged population | 000 | 5 | NIH | 6/25/2024 | $0 |
| 2024 | 2020 | HESPEROS, INC | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES029892 | Development of an integrated 4-organ animal model | 000 | 3 | NIH | 5/1/2024 | $0 |
|
| Issue Date FY: 2023 ( Subtotal = $854,765 ) |
| 2023 | 2023 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44HL140920 | HLS-Development of a cardiac ischemia model in an organ-on-a-chip platform | 000 | 3 | NIH | 2/21/2023 | $854,765 |
| 2023 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44TR001326 | Automation and validation of human on a chip systems for drug discovery | 000 | 5 | NIH | 4/5/2023 | $0 |
| 2023 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG058330 | Functional integrated human-on-a-chip systems for Alzheimer's research | 000 | 3 | NIH | 9/21/2023 | $0 |
| 2023 | 2019 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R43AG060886 | Human on a chip system to investigate genetic risk factors in Alzheimer's disease | 000 | 2 | NIH | 12/7/2022 | $0 |
|
| Issue Date FY: 2022 ( Subtotal = $4,193,185 ) |
| 2022 | 2022 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG059511 | Human on a chip systems to investigate disease comorbidities common in the aged population | 000 | 5 | NIH | 5/17/2022 | $1,483,966 |
| 2022 | 2022 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG071386 | Modulatory Role of Blood-Brain-Barrier and Enzymatic Activity in an Innovative Human Model of Cholinergic Drug Induced Dementia | 000 | 2 | NIH | 8/16/2022 | $902,299 |
| 2022 | 2022 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG071386 | Modulatory Role of Blood-Brain-Barrier and Enzymatic Activity in an Innovative Human Model of Cholinergic Drug Induced Dementia | 001 | 2 | NIH | 8/18/2022 | $162,742 |
| 2022 | 2022 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44HL140920 | HLS-Development of a cardiac ischemia model in an organ-on-a-chip platform | 000 | 2 | NIH | 2/25/2022 | $854,765 |
| 2022 | 2022 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES032360 | Biodistribution and PK modeling of rat vs. human systems | 001 | 3 | NIH | 4/13/2022 | $35,173 |
| 2022 | 2022 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES032360 | Biodistribution and PK modeling of rat vs. human systems | 000 | 3 | NIH | 2/24/2022 | $754,240 |
| 2022 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG058330 | Functional integrated human-on-a-chip systems for Alzheimer's research | 000 | 3 | NIH | 11/5/2021 | $0 |
| 2022 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES029892 | Development of an integrated 4-organ animal model | 000 | 3 | NIH | 7/22/2022 | $0 |
| 2022 | 2018 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R43HL140920 | HLS-Development of a cardiac ischemia model in an organ-on-a-chip platform | 000 | 1 | NIH | 4/19/2022 | $0 |
|
| Issue Date FY: 2021 ( Subtotal = $3,228,523 ) |
| 2021 | 2021 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG071386 | Modulatory Role of Blood-Brain-Barrier and Enzymatic Activity in an Innovative Human Model of Cholinergic Drug Induced Dementia | 000 | 1 | NIH | 8/10/2021 | $902,320 |
| 2021 | 2021 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44TR001326 | Automation and validation of human on a chip systems for drug discovery | 000 | 5 | NIH | 9/3/2021 | $77,997 |
| 2021 | 2021 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG059511 | Human on a chip systems to investigate disease comorbidities common in the aged population | 001 | 4 | NIH | 5/6/2021 | $1,483,966 |
| 2021 | 2021 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES032360 | Biodistribution and PK modeling of rat vs. human systems | 001 | 2 | NIH | 2/24/2021 | $754,240 |
| 2021 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES032360 | Biodistribution and PK modeling of rat vs. human systems | 000 | 1 | NIH | 10/28/2020 | $10,000 |
| 2021 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES032360 | Biodistribution and PK modeling of rat vs. human systems | 002 | 1 | NIH | 8/13/2021 | $0 |
| 2021 | 2019 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R43AG060886 | Human on a chip system to investigate genetic risk factors in Alzheimer's disease | 000 | 2 | NIH | 5/13/2021 | $0 |
| 2021 | 2019 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG059511 | Human on a chip systems to investigate disease comorbidities common in the aged population | 000 | 2 | NIH | 2/1/2021 | $0 |
|
| Issue Date FY: 2020 ( Subtotal = $5,430,718 ) |
| 2020 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44TR001326 | Automation and validation of human on a chip systems for drug discovery | 000 | 4 | NIH | 12/31/2019 | $73,535 |
| 2020 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44TR001326 | Automation and validation of human on a chip systems for drug discovery | 002 | 5 | NIH | 9/1/2020 | $1,330,924 |
| 2020 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44TR001326 | Automation and validation of human on a chip systems for drug discovery | 002 | 5 | NIH | 9/1/2020 | $73,535 |
| 2020 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG058330 | Functional integrated human-on-a-chip systems for Alzheimer's research | 001 | 3 | NIH | 1/22/2020 | $1,507,753 |
| 2020 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG059511 | Human on a chip systems to investigate disease comorbidities common in the aged population | 001 | 3 | NIH | 5/8/2020 | $1,483,966 |
| 2020 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES032360 | Biodistribution and PK modeling of rat vs. human systems | 000 | 1 | NIH | 9/10/2020 | $216,260 |
| 2020 | 2020 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES029892 | Development of an integrated 4-organ animal model | 001 | 3 | NIH | 8/10/2020 | $744,745 |
| 2020 | 2019 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG059511 | Human on a chip systems to investigate disease comorbidities common in the aged population | 000 | 2 | NIH | 5/5/2020 | $0 |
| 2020 | 2018 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44ES029892 | Development of an integrated 4-organ animal model | 000 | 1 | NIH | 2/1/2020 | $0 |
| 2020 | 2018 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R43HL140920 | HLS-Development of a cardiac ischemia model in an organ-on-a-chip platform | 000 | 1 | NIH | 8/7/2020 | $0 |
| 2020 | 2017 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44AG058330 | Functional integrated human-on-a-chip systems for Alzheimer's research | 000 | 1 | NIH | 1/10/2020 | $0 |
| 2020 | 2017 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R43DK116589 | Integration of a kidney module into a 4-organ human-on-a-chip system. | 000 | 1 | NIH | 1/18/2020 | $0 |
| 2020 | 2017 | HESPEROS, INC. | 12501 RESEARCH PKWY STE 100 | ORLANDO | FL | 32826-2908 | ORANGE | USA | R44TR001326 | Automation and validation of human on a chip systems for drug discovery | 001 | 2 | NIH | 3/27/2020 | $0 |
|
| Issue Date FY: 2019 ( Subtotal = $4,412,467 ) (Continued on the next page) |
| 2019 | 2019 | HESPEROS, INC | 3259 PROGRESS DR, # 158 | ORLANDO | FL | 32826-3230 | ORANGE | USA | R44TR001326 | Automation and validation of human on a chip systems for drug discovery | 002 | 4 | NIH | 9/21/2019 | $81,964 |
| 2019 | 2019 | HESPEROS, INC | 3259 PROGRESS DR, # 158 | ORLANDO | FL | 32826-3230 | ORANGE | USA | R44TR001326 | Automation and validation of human on a chip systems for drug discovery | 004 | 4 | NIH | 9/25/2019 | -$1 |
| 2019 | 2019 | HESPEROS, INC | 3259 PROGRESS DR, # 158 | ORLANDO | FL | 32826-3230 | ORANGE | USA | R44AG059511 | Human on a chip systems to investigate disease comorbidities common in the aged population | 000 | 2 | NIH | 3/18/2019 | $224,999 |
| 2019 | 2019 | HESPEROS, INC | 3259 PROGRESS DR, # 158 | ORLANDO | FL | 32826-3230 | ORANGE | USA | R43AG060886 | Human on a chip system to investigate genetic risk factors in Alzheimer's disease | 000 | 2 | NIH | 5/30/2019 | $335,252 |
|