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 | Issue Date FY: 2025 ( Subtotal = $15,927,994 ) (Continued on the next page) |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH137441 | Tracking the dynamic trajectory of behavioral, physiological, and neurobiological stress responses in female adolescents at high and low familial risk for depression. | 000 | 1 | NIH | 4/10/2025 | $792,441 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | T32DA015036 | Training in Drug Abuse and Brain Imaging | 001 | 24 | NIH | 6/18/2025 | $5,314 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K24DA061976 | Mentoring in Patient-Oriented Research on Substance Use Disorders | 000 | 1 | NIH | 12/24/2024 | $208,575 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH136052 | MDMA Mechanisms of Prohedonic Efficacy: A Reverse Translational Approach | 000 | 1 | NIH | 3/24/2025 | $766,842 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R21MH138861 | Observing brain lactate dynamics during a working memory task in first episode and chronic schizophrenia | 000 | 1 | NIH | 11/15/2024 | $246,000 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH133268 | Next steps for PTSD genomics: from loci to function | 000 | 2 | NIH | 4/16/2025 | $689,594 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K23MH137459 | A Multilevel Characterization of Sensory Cortical Disinhibition in Post-Traumatic Intrusions | 000 | 2 | NIH | 5/23/2025 | $179,031 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01NS129188 | Human iPSC-Based Personalized Cell Therapy of PD | 000 | 3 | NIH | 4/18/2025 | $689,100 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01NS127391 | Crosstalk Between Nurr1 and Risk Factors of Parkinson's Disease and its Regulation by Nurr1's Ligands | 000 | 3 | NIH | 4/25/2025 | $432,440 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R37MH068376 | Neuroimaging Studies of Reward Processing in Depression | 000 | 20 | NIH | 2/19/2025 | $649,636 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH135899 | Leveraging Machine Learning Approaches to Understand Mechanisms of Exposure Therapy in Real-World Settings | 000 | 2 | NIH | 2/14/2025 | $659,178 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH135844 | Harnessing smartphones for real-time detection of affective disturbance and future depression risk in adolescents | 000 | 1 | NIH | 1/31/2025 | $759,581 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH129374 | Parent interpretation bias as a key mechanism of intergenerational transmission of anxiety | 001 | 3 | NIH | 1/28/2025 | $111,618 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH129374 | Parent interpretation bias as a key mechanism of intergenerational transmission of anxiety | 003 | 3 | NIH | 4/28/2025 | $0 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH129374 | Parent interpretation bias as a key mechanism of intergenerational transmission of anxiety | 002 | 3 | NIH | 4/25/2025 | $0 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH129374 | Parent interpretation bias as a key mechanism of intergenerational transmission of anxiety | 000 | 3 | NIH | 1/27/2025 | $634,317 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH134074 | Imaging the Functional State of the D2high Receptor in drug induced dopamine supersensitivity in schizophrenia | 000 | 2 | NIH | 1/27/2025 | $513,604 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH121617 | Mobile Measures of Threat Sensitivity for Cross-sectional and Longitudinal Assessment | 002 | 5 | NIH | 4/24/2025 | $0 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH121617 | Mobile Measures of Threat Sensitivity for Cross-sectional and Longitudinal Assessment | 001 | 5 | NIH | 12/5/2024 | $70,946 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH121617 | Mobile Measures of Threat Sensitivity for Cross-sectional and Longitudinal Assessment | 000 | 5 | NIH | 11/7/2024 | $649,051 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH126000 | Empirical validation of a cerebellar-cortical hallucination circuit | 000 | 4 | NIH | 1/13/2025 | $570,762 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R21MH136479 | Utilizing circRNA transcriptomics for functional characterization of psychiatric GWAS | 000 | 2 | NIH | 1/8/2025 | $174,250 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R21MH133114 | Measuring brain lactate and other metabolites in schizophrenia at 3T using an enhanced MR spectroscopy approach | 000 | 2 | NIH | 4/24/2025 | $174,250 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K00HD112293 | Elucidating interactions among early life adversity, sleep architecture, and immune function | 000 | 5 | NIH | 12/9/2024 | $98,546 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH135093 | Molecular Mechanisms of Aging in Schizophrenia: Implications of Bioenergetic Metabolism and Redox Biology | 000 | 2 | NIH | 12/10/2024 | $762,422 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K23MH132900 | Shared and differential vulnerabilities of stress and reward processing in psychosis-risk syndromes or early-stage depression | 000 | 2 | NIH | 11/4/2024 | $178,416 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01DA058315 | Impact of prescription stimulants on the drug overdose epidemic | 000 | 3 | NIH | 4/24/2025 | $721,783 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K08MH130802 | Understanding Foxp2-Mediated Molecular Signaling in Fear Learning | 000 | 3 | NIH | 4/14/2025 | $193,993 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH139697 | Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression | 000 | 1 | NIH | 6/9/2025 | $777,016 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01HD104656 | Disruptions in the brain reward system through postnatal exposure to GABA agonists and anesthetics | 000 | 4 | NIH | 4/3/2025 | $394,336 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | T32MH125786 | Training to Enhance Alignment of Psychiatry and Neuroscience | 000 | 5 | NIH | 6/9/2025 | $389,290 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K01MH129828 | Multimodal characterization of affective visual processing in the early aftermath of trauma | 000 | 3 | NIH | 11/14/2024 | $179,707 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K01MH122672 | Inducing Mirth to Improve Memory in Depression | 000 | 5 | NIH | 6/13/2025 | $174,352 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01DA047575 | Neural and Behavioral Consequences of Chronic THC Exposure During Adolescence | 000 | 6 | NIH | 5/27/2025 | $1,179,649 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01AT011002 | Mechanisms and Predictors of Change in App-Based Mindfulness Training for Adolescents | 000 | 5 | NIH | 6/30/2025 | $567,556 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH117292 | Site 3/3, Understanding PTSD through Postmortem Targeted Brain Multiomics | 000 | 6 | NIH | 5/27/2025 | $1,020,847 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | T32DA015036 | Training in Drug Abuse and Brain Imaging | 000 | 24 | NIH | 5/15/2025 | $337,588 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH108665 | Cell Type Specific Genomic and Functional Dissection of Fear-Off Amygdala Pathways | 002 | 10 | NIH | 5/1/2025 | $659,823 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH134885 | 3/5- Biomarkers to Enhance Early Schizophrenia Treatment (BEEST) | 000 | 1 | NIH | 4/29/2025 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH125740 | SCH: INT: Collaborative Research: Context-Adaptive Multimodal Informatics for Psychiatric Discharge Planning | 000 | 4 | NIH | 6/11/2025 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH095809 | Early Life Stress and Depression: Molecular and Functional Imaging Approaches | 000 | 9 | NIH | 3/8/2025 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH116969 | Predicting the onset of depression in at-risk adolescents from endophenotype profiles | 000 | 5 | NIH | 10/23/2024 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K99MH133869 | Amygdala Circuit Mechanisms for Stress-escalated Aggression | 000 | 2 | NIH | 5/17/2025 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K99MH133869 | Amygdala Circuit Mechanisms for Stress-escalated Aggression | 001 | 2 | NIH | 6/18/2025 | -$51,749 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | P50MH115846 | Laboratory for Early Psychosis Research (LEAP) | 000 | 6 | NIH | 11/20/2024 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH108665 | Cell Type Specific Genomic and Functional Dissection of Fear-Off Amygdala Pathways | 001 | 9 | NIH | 4/30/2025 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH108665 | Cell Type Specific Genomic and Functional Dissection of Fear-Off Amygdala Pathways | 000 | 9 | NIH | 4/29/2025 | $0 |
| | 2025 | 2023 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH111676 | Computational mechanisms of memory disruption in depression | 000 | 5 | NIH | 3/20/2025 | $0 |
| | 2025 | 2023 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | UG3DA058544 | Antibody-based therapy for fentanyl-related opioid use disorder | 000 | 1 | NIH | 10/17/2024 | $0 |
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