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 | Issue Date FY: 2025 ( Subtotal = $6,601,341 ) |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH121617 | Mobile Measures of Threat Sensitivity for Cross-sectional and Longitudinal Assessment | 000 | 5 | NIH | 11/7/2024 | $649,051 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH136052 | MDMA Mechanisms of Prohedonic Efficacy: A Reverse Translational Approach | 000 | 1 | NIH | 3/24/2025 | $766,842 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R37MH068376 | Neuroimaging Studies of Reward Processing in Depression | 000 | 20 | NIH | 2/19/2025 | $649,636 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R21MH136479 | Utilizing circRNA transcriptomics for functional characterization of psychiatric GWAS | 000 | 2 | NIH | 1/8/2025 | $174,250 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K01MH129828 | Multimodal characterization of affective visual processing in the early aftermath of trauma | 000 | 3 | NIH | 11/14/2024 | $179,707 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K24DA061976 | Mentoring in Patient-Oriented Research on Substance Use Disorders | 000 | 1 | NIH | 12/24/2024 | $208,575 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH126000 | Empirical validation of a cerebellar-cortical hallucination circuit | 000 | 4 | NIH | 1/13/2025 | $570,762 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH129374 | Parent interpretation bias as a key mechanism of intergenerational transmission of anxiety | 000 | 3 | NIH | 1/27/2025 | $634,317 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH134074 | Imaging the Functional State of the D2high Receptor in drug induced dopamine supersensitivity in schizophrenia | 000 | 2 | NIH | 1/27/2025 | $513,604 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH121617 | Mobile Measures of Threat Sensitivity for Cross-sectional and Longitudinal Assessment | 001 | 5 | NIH | 12/5/2024 | $70,946 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH129374 | Parent interpretation bias as a key mechanism of intergenerational transmission of anxiety | 001 | 3 | NIH | 1/28/2025 | $111,618 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH135844 | Harnessing smartphones for real-time detection of affective disturbance and future depression risk in adolescents | 000 | 1 | NIH | 1/31/2025 | $759,581 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K00HD112293 | Elucidating interactions among early life adversity, sleep architecture, and immune function | 000 | 5 | NIH | 12/9/2024 | $98,546 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R21MH138861 | Observing brain lactate dynamics during a working memory task in first episode and chronic schizophrenia | 000 | 1 | NIH | 11/15/2024 | $246,000 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH135093 | Molecular Mechanisms of Aging in Schizophrenia: Implications of Bioenergetic Metabolism and Redox Biology | 000 | 2 | NIH | 12/10/2024 | $762,422 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH135899 | Leveraging Machine Learning Approaches to Understand Mechanisms of Exposure Therapy in Real-World Settings | 000 | 2 | NIH | 2/14/2025 | $659,178 |
| | 2025 | 2025 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K23MH132900 | Shared and differential vulnerabilities of stress and reward processing in psychosis-risk syndromes or early-stage depression | 000 | 2 | NIH | 11/4/2024 | $178,416 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH095809 | Early Life Stress and Depression: Molecular and Functional Imaging Approaches | 000 | 9 | NIH | 3/8/2025 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | P50MH115846 | Laboratory for Early Psychosis Research (LEAP) | 000 | 6 | NIH | 11/20/2024 | $0 |
| | 2025 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH116969 | Predicting the onset of depression in at-risk adolescents from endophenotype profiles | 000 | 5 | NIH | 10/23/2024 | $0 |
| | 2025 | 2023 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01HD093680 | Behavioral and Neural Phenotypes of Primary Dysmenorrhea in Adolescents | 000 | 6 | NIH | 3/27/2025 | $0 |
| | 2025 | 2023 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH111676 | Computational mechanisms of memory disruption in depression | 000 | 5 | NIH | 3/20/2025 | $0 |
| | 2025 | 2023 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K23MH121781 | Energy Metabolism Markers of Cognitive Function in Early Psychosis and Risk | 000 | 5 | NIH | 11/21/2024 | $0 |
| | 2025 | 2023 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH114982 | Molecular Mechanisms and Biomarkers for Disease Progression from Prodrome to Early Psychosis | 000 | 5 | NIH | 12/9/2024 | $0 |
| | 2025 | 2023 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH117012 | Neuroprogression across the Psychosis Spectrum in the Early Course of Illness | 000 | 5 | NIH | 1/13/2025 | $0 |
| | 2025 | 2023 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | UG3DA058544 | Antibody-based therapy for fentanyl-related opioid use disorder | 000 | 1 | NIH | 10/17/2024 | $0 |
| | 2025 | 2022 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R61MH121640 | Individually targeted neuromodulation for contamination-based OCD | 000 | 2 | NIH | 10/22/2024 | -$632,110 |
| | 2025 | 2022 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R21MH125076 | Identification of Trauma-related Features in EHR Data for Patients with Psychosis and Mood Disorders | 000 | 2 | NIH | 10/22/2024 | $0 |
| | 2025 | 2021 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH111542 | Brain and Behavior Mechanisms of Irritability and Cognitive Flexibility in Children | 000 | 6 | NIH | 3/31/2025 | $0 |
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| Issue Date FY: 2024 ( Subtotal = $31,969,506 ) (Continued on the next page) |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01DA021409 | Human dopamine transporter gene: variation and transcriptional regulation | 000 | 15 | NIH | 7/31/2024 | $410,000 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | P50MH119467 | Novel Treatment Targets For Affective Disorders Through Cross-Species Investigation of Approach/Avoidance Decision Making | 000 | 5 | NIH | 3/19/2024 | $2,836,693 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K23DA050808 | Improving Treatment Engagement in Individuals with Co-occurring Substance Use and Psychosis: A Telemedicine Family-Based Approach | 000 | 5 | NIH | 5/29/2024 | $189,232 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01HD102974 | Understanding the transgenerational epigenetic effect of maternal psychosocial trauma exposure on infants via lncRNA-sequencing | 000 | 5 | NIH | 7/15/2024 | $9,800 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01AG066670 | Effects of Orally Administered Nicotinamide Riboside on Bioenergetic Metabolism, Oxidative Stress and Cognition in Mild Cognitive Impairment and Mild Alzheimer's Dementia | 000 | 5 | NIH | 6/10/2024 | $346,505 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01AG066670 | Effects of Orally Administered Nicotinamide Riboside on Bioenergetic Metabolism, Oxidative Stress and Cognition in Mild Cognitive Impairment and Mild Alzheimer's Dementia | 000 | 5 | NIH | 6/10/2024 | $473,048 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K23DA050780 | Increasing Women's Engagement in Medication Treatment for Opioid Use Disorder through Digital Intervention | 000 | 5 | NIH | 6/26/2024 | $187,540 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01AT011002 | Supplemental: Neural and cognitive propensity for trait rumination in adolescents: a multimodal study with ecological momentary assessments and MRI | 000 | 4 | NIH | 6/3/2024 | $614,026 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01AT011002 | Supplemental: Neural and cognitive propensity for trait rumination in adolescents: a multimodal study with ecological momentary assessments and MRI | 001 | 4 | NIH | 6/26/2024 | $269,872 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K24AA025977 | Mentoring in Patient-Oriented Neuroscience Research | 000 | 8 | NIH | 8/6/2024 | $162,796 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01DA017846 | Early Stress and the Neurobiology of Susceptibility and Resilience to Substance Use Disorders | 000 | 15 | NIH | 6/26/2024 | $733,785 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | K23MH126193 | Interpretation Bias as a Mechanism of Treatment Response in OCD | 000 | 3 | NIH | 12/15/2023 | $181,688 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH125740 | SCH: INT: Collaborative Research: Context-Adaptive Multimodal Informatics for Psychiatric Discharge Planning | 002 | 4 | NIH | 6/17/2024 | $27,667 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH125740 | SCH: INT: Collaborative Research: Context-Adaptive Multimodal Informatics for Psychiatric Discharge Planning | 001 | 4 | NIH | 4/2/2024 | $0 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH125740 | SCH: INT: Collaborative Research: Context-Adaptive Multimodal Informatics for Psychiatric Discharge Planning | 000 | 4 | NIH | 2/26/2024 | $249,004 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH095809 | Early Life Stress and Depression: Molecular and Functional Imaging Approaches | 000 | 9 | NIH | 5/15/2024 | $778,023 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH135899 | Leveraging Machine Learning Approaches to Understand Mechanisms of Exposure Therapy in Real-World Settings | 001 | 1 | NIH | 5/9/2024 | $78,298 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R01MH135899 | Leveraging Machine Learning Approaches to Understand Mechanisms of Exposure Therapy in Real-World Settings | 000 | 1 | NIH | 3/21/2024 | $720,689 |
| | 2024 | 2024 | THE MCLEAN HOSPITAL CORPORATION | 115 MILL ST | BELMONT | MA | 02478-1064 | MIDDLESEX | USA | R37MH068376 | Neuroimaging Studies of Reward Processing in Depression | 001 | 19 | NIH | 7/18/2024 | $76,182 |
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