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 | Issue Date FY: 2025 ( Subtotal = $33,176,118 ) (Continued on the next page) |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC021996 | Advancement of an Implantable Microphone | 000 | 1 | NIH | 4/8/2025 | $674,021 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | K23EY035342 | Genetics of central serous chorioretinopathy and choroidal thickening | 000 | 2 | NIH | 4/18/2025 | $276,856 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | K08DC019128 | Neural Mechanisms Underlying the Auditory Phenotype of Mild Traumatic Brain Injury | 000 | 5 | NIH | 11/26/2024 | $186,095 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY022305 | NEIGHBORHOOD Consortium for POAG Genetics | 000 | 13 | NIH | 2/14/2025 | $395,003 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC011805 | Imaging genetics of laryngeal dystonia | 000 | 15 | NIH | 7/1/2025 | $594,364 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY020928 | Genetic and Environmental Risk Factors for Exfoliation Syndrome and Glaucoma | 000 | 13 | NIH | 9/17/2025 | $426,396 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | K12EY016335 | Harvard-Vision Clinical Scientist Development Program | 000 | 20 | NIH | 3/27/2025 | $3,990 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY014943 | Long-term Follow-up of the Systemic Immunosuppressive Therapy for Eye Diseases Cohort | 001 | 12 | NIH | 8/29/2025 | $0 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY014943 | Long-term Follow-up of the Systemic Immunosuppressive Therapy for Eye Diseases Cohort | 000 | 12 | NIH | 8/15/2025 | $2,236,075 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY012910 | Precision Medicine for Inherited Retinal Degenerations | 000 | 28 | NIH | 7/29/2025 | $641,107 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | U24DC020849 | Massachusetts Eye and Ear/ Harvard Initiative for the NIDCD National Human Ear Resource Network | 001 | 4 | NIH | 8/15/2025 | $595,000 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC021439 | Development and Plasticity of Neural Circuits Underlying Sound Encoding | 000 | 2 | NIH | 4/23/2025 | $605,722 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | U01DP006822 | DP24-081 The Glaucoma and Retinopathy Screening Study | 00 | 2 | CDC | 6/18/2025 | $750,000 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01NS124228 | Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia | 000 | 3 | NIH | 4/30/2025 | $674,349 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | P50DC019900 | Next-generation clinical phenotyping and pathophysiology of laryngeal dystonia and voice tremor | 001 | 5 | NIH | 8/8/2025 | $682,489 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | P50DC015857 | Cochlear Synaptopathy: Prevalence, Diagnosis and Functional Consequences | 000 | 9 | NIH | 8/13/2025 | $2,684,343 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC020190 | Development of Gene Therapy for Hereditary Deafness using Rational Protein Engineering | 000 | 4 | NIH | 5/29/2025 | $655,725 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | U24DC013983 | NIDCD National Temporal Bone Hearing and Balance Pathology Resource Registry | 002 | 10 | NIH | 1/2/2025 | $127,582 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | K23EY035734 | Clinical and functional assessment of glaucoma-associated mitochondrial gene variants to facilitate precision eye care | 000 | 2 | NIH | 11/21/2024 | $269,782 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R13DC013748 | International Hearing Aid Conference (IHCON) 2024 | 000 | 9 | NIH | 12/18/2024 | $100 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EB036978 | Fluorescence lifetime-based intraoperative imaging system for sarcoma surgeries | 000 | 1 | NIH | 1/13/2025 | $567,340 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EB036978 | Fluorescence lifetime-based intraoperative imaging system for sarcoma surgeries | 001 | 1 | NIH | 8/21/2025 | $70,610 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC007910 | Measuring and Modeling the Cochlear Organ-of-Corti Motions Responsible for Inner-and Outer-Hair-Cell Drives and Amplification | 000 | 17 | NIH | 5/28/2025 | $696,198 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | T32DC000020 | Research Training in Otolaryngology | 000 | 33 | NIH | 6/13/2025 | $88,420 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R00MH127471 | Distributed Neural Activity Patterns Underlying Practice-Based Learning | 000 | 3 | NIH | 9/22/2025 | $223,756 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R21DC022085 | In-silico screen and in-vivo evaluation of FDA-approved drugs to treat noise-induced hearing loss | 000 | 1 | NIH | 9/11/2025 | $473,749 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | P01AI083214 | Harvard-wide Program on Antibiotic Resistance | 000 | 17 | NIH | 3/5/2025 | $2,252,080 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R21DC022922 | Human Organ of Corti Micromechanics | 000 | 1 | NIH | 7/23/2025 | $637,500 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC000188 | Cochlear synaptopathy in noise-induced and age-related hearing loss: mechanisms and treatments | 001 | 44 | NIH | 6/9/2025 | $68,125 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC000188 | Cochlear synaptopathy in noise-induced and age-related hearing loss: mechanisms and treatments | 000 | 44 | NIH | 2/25/2025 | $613,127 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | K23DE029811 | Dissecting temporal and spatial dynamics of immunotherapy resistance | 000 | 5 | NIH | 3/20/2025 | $173,772 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | K01EB037630 | Developing a library of near-infrared fluorophores for multiplexed in vivo fluorescence lifetime imaging of disease biomarkers. | 000 | 1 | NIH | 8/1/2025 | $169,543 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY019703 | Cell Biology of Astrocyte-Ganglion Cell Interactions in the Retina and Optic Nerve | 002 | 15 | NIH | 4/9/2025 | $425,000 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY036648 | Genetic profiling of childhood glaucoma in India | 000 | 2 | NIH | 9/19/2025 | $361,250 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | F32DC022491 | Investigating the role of tip link biophysics on MET function | 000 | 2 | NIH | 7/15/2025 | $75,520 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC021981 | Vestibular implant tested in patients with peripheral vestibular damage: effects on spatial orientation, navigation, and neuropsychologic function | 000 | 2 | NIH | 7/30/2025 | $509,361 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC021981 | Vestibular implant tested in patients with peripheral vestibular damage: effects on spatial orientation, navigation, and neuropsychologic function | 001 | 2 | NIH | 8/6/2025 | $112,008 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY036444 | Point-of-Care Metagenomics for Rapid Detection of pathogens and Antimicrobial Resistance in Sight-Threatening Ocular Infections | 000 | 2 | NIH | 9/19/2025 | $361,250 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY035717 | Finding Missing Genetic Causality of Inherited Retinal Degenerations | 001 | 2 | NIH | 7/7/2025 | $684,891 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | U01TR005352 | AAV-mediated editing to treat human autosomal dominant hearing loss DFNA41 and DFNA2 | 000 | 2 | NIH | 7/31/2025 | $3,227,062 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01AG075532 | Contribution of vestibular dysfunction and its central multisensory integration to imbalance in aging | 001 | 2 | NIH | 7/25/2025 | $573,369 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY036137 | Rapid Diagnosis of Ocular Infections using a Sensitive and Highly Multiplexed Broad Pathogen Detection Assay | 000 | 2 | NIH | 7/7/2025 | $425,000 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | K08DC022004 | Plasticity of auditory cortex microglia and perineuronal nets after hearing loss | 000 | 2 | NIH | 5/22/2025 | $194,400 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01EY036518 | Enhancing Glaucoma Risk Prediction through Advanced Genomics and Machine Learning | 000 | 2 | NIH | 9/22/2025 | $592,959 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC021606 | Improving Cochlear Implant Outcomes Through Modeling and Programming Strategies Based on Human Inner Ear Pathology | 000 | 3 | NIH | 7/29/2025 | $600,809 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC012142 | Perceptual implications of cochlear implant electrode-neuron interfaces | 000 | 15 | NIH | 5/23/2025 | $582,301 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DE033427 | Fluorescence lifetime-based tumor contrast enhancement using exogenous probes | 000 | 4 | NIH | 8/6/2025 | $450,915 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R01DC020322 | Determination of Hair Cell Fate from Postnatal Cochlear Supporting Cells | 000 | 4 | NIH | 4/23/2025 | $617,363 |
| | 2025 | 2025 | MASSACHUSETTS EYE AND EAR INFIRMARY | 243 CHARLES ST | BOSTON | MA | 02114-3002 | SUFFOLK | USA | R00EY032110 | Elucidating the molecular and cellular mechanisms underlying cone survival in the peripheral retina in mouse models of Retinitis Pigmentosa | 000 | 5 | NIH | 4/4/2025 | $249,000 |
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