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 | Issue Date FY: 2025 ( Subtotal = $100,869,012 ) (Continued on the next page) |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | UM1CA081457 | Pediatric Brain Tumor Consortium A multi-institutional consortium devoted to novel phase I and II clinical evaluations of experimental treatment approaches for pediatric CNS tumors | 000 | 25 | NIH | 4/17/2025 | $3,793,439 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA172152 | Role of the SWI/SNF complex in tumor suppression | 004 | 13 | NIH | 5/22/2025 | $45,045 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA172152 | Role of the SWI/SNF complex in tumor suppression | 003 | 13 | NIH | 4/4/2025 | $405,401 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | T32AI106700 | Training in the Design and Development of Infectious Disease Therapeutics | 001 | 10 | NIH | 8/6/2025 | $3,965 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | T32AI106700 | Training in the Design and Development of Infectious Disease Therapeutics | 000 | 10 | NIH | 4/24/2025 | $251,443 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | P30CA021765 | Cancer Center Support Grant (CCSG) | 004 | 46 | NIH | 6/27/2025 | $6,642,609 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA113794 | The function of Snf5 (SMARCB1), an epigenetic tumor suppressor | 001 | 21 | NIH | 6/13/2025 | $42,351 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA113794 | The function of Snf5 (SMARCB1), an epigenetic tumor suppressor | 000 | 21 | NIH | 11/21/2024 | $381,159 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R25CA023944 | PEDIATRIC ONCOLOGY EDUCATION (YEARS 38 - 42) | 001 | 41 | NIH | 5/22/2025 | $43,199 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R25CA023944 | PEDIATRIC ONCOLOGY EDUCATION (YEARS 38 - 42) | 000 | 41 | NIH | 4/30/2025 | $388,801 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | U24CA055727 | Childhood Cancer Survivorship Study | 002 | 31 | NIH | 5/27/2025 | $0 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | U24CA055727 | Childhood Cancer Survivorship Study | 001 | 31 | NIH | 3/5/2025 | $3,024,600 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AG075869 | REGULATION OF PROTEOSTASIS AND TAUOPATHY BY MALTOSE-INDUCED SIGNALING | 001 | 2 | NIH | 8/4/2025 | $37,000 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AG075869 | REGULATION OF PROTEOSTASIS AND TAUOPATHY BY MALTOSE-INDUCED SIGNALING | 000 | 2 | NIH | 1/23/2025 | $416,250 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01DK140461 | Extracellular matrix in vertebrate hematopoietic stem cell specification | 000 | 2 | NIH | 6/24/2025 | $370,000 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R37AI105887 | Metabolic checkpoint in dendritic cell subsets and adaptive immunity | 000 | 12 | NIH | 12/3/2024 | $455,000 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R21CA280187 | Caregiver Education with Interactive Neurodevelopmental Games to Improve Cognitive and Social-Emotional Outcomes in Infants Undergoing Treatment for Medulloblastoma | 000 | 2 | NIH | 6/12/2025 | $217,600 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI128756 | Bioactivities of pneumococcal cell wall in neuropathogenesis | 000 | 9 | NIH | 1/21/2025 | $441,350 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA289881 | Targetable epigenetic modifiers that promote neuroblastoma malignancy and plasticity | 000 | 1 | NIH | 1/10/2025 | $718,113 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R21AI178085 | Trivalent Live Attenuated Vaccines for Bacterial Acute Otitis Media | 000 | 2 | NIH | 12/9/2024 | $220,675 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35GM157243 | Deciphering the genetic regulation of bacterial heterogeneity in response to antibiotic stress using single-cell transcriptomics | 000 | 1 | NIH | 12/24/2024 | $462,500 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01EY037117 | The Role of Müller Glia in Acute and Chronic Response to Stress, Injury, and Disease in the Retina | 000 | 1 | NIH | 1/15/2025 | $606,034 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | U01CA263969 | In Vivo Testing of Novel Drug Combinations for Pediatric Soft Tissue Sarcomas | 001 | 5 | NIH | 7/7/2025 | $767,363 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35GM155423 | Chemical approaches for targeting ribonucleoprotein assemblies | 000 | 2 | NIH | 7/14/2025 | $462,500 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA290805 | Targeting the chromatin binding domains of BPTF for neuroblastoma epigenetic therapy | 000 | 1 | NIH | 12/30/2024 | $738,024 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | T32HL176447 | Basic and Translational Research Training in Pediatric Classical Hematology | 000 | 1 | NIH | 12/26/2024 | $252,285 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01DC021511 | Sensory-evoked adenosine release in cortical plasticity | 000 | 2 | NIH | 5/6/2025 | $561,784 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | K99DK134844 | Hematopoietic stem cell defects in Diamond-Blackfan Anemia | 000 | 2 | NIH | 4/8/2025 | $90,000 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01NS121114 | Understanding the sequence and structural determinants of phase behavior of ALS-causing proteins | 000 | 5 | NIH | 2/20/2025 | $561,572 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01NS121114 | Understanding the sequence and structural determinants of phase behavior of ALS-causing proteins | 001 | 5 | NIH | 8/5/2025 | $62,397 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI170765 | Targeting NuoD for the treatment of H. pylori | 000 | 3 | NIH | 4/15/2025 | $844,980 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | K08CA255569 | WT1 as an oncogene and therapeutic target in anaplastic Wilms tumor | 000 | 5 | NIH | 12/12/2024 | $194,741 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R00AI159295 | Cis-interaction mediated CD28 costimulation | 000 | 4 | NIH | 8/18/2025 | $249,000 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI168214 | Consequences of Direct Viral-Bacterial Interactions | 000 | 4 | NIH | 12/9/2024 | $487,212 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01MH136215 | Cooperative dysfunction of thalamocortical and cerebellar inputs to the auditory cortex in 22q11.2 deletion syndrome model of schizophrenia. | 001 | 1 | NIH | 11/29/2024 | $9,436 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01MH136215 | Cooperative dysfunction of thalamocortical and cerebellar inputs to the auditory cortex in 22q11.2 deletion syndrome model of schizophrenia. | 000 | 1 | NIH | 11/27/2024 | $721,599 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01NS139519 | Polarity Signals Coordinate Neuronal Differentiation & Nuclear Organization | 000 | 1 | NIH | 11/22/2024 | $676,388 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI187465 | Epigenetic Checkpoint Regulation of Naive T-cell Quiescence and Peripheral Tolerance | 000 | 1 | NIH | 7/22/2025 | $3,428,212 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI131703 | Regulation of T cell memory in tissue immunity | 000 | 6 | NIH | 11/13/2024 | $538,352 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35GM122462 | Structure and functional mechanisms of molecular chaperones and protein kinases | 002 | 9 | NIH | 8/5/2025 | $76,430 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35GM122462 | Structure and functional mechanisms of molecular chaperones and protein kinases | 001 | 9 | NIH | 2/24/2025 | $687,854 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM144566 | Structural Basis of Programmable DNA-Insertion via Cryo-EM Studies of CRISPR-Associated TnsC | 004 | 4 | NIH | 8/7/2025 | $38,219 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM144566 | Structural Basis of Programmable DNA-Insertion via Cryo-EM Studies of CRISPR-Associated TnsC | 003 | 4 | NIH | 12/9/2024 | $343,981 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01EY036689 | The Role of Modular Super-Enhancers in the Developing Murine and Human Retina | 000 | 2 | NIH | 3/31/2025 | $596,514 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | U01CA294103 | Discovering the mechanisms underlying oncogenesis by ZFTA-RELA and pinpointing therapeutic targets. | 000 | 2 | NIH | 8/14/2025 | $601,250 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | U01AI176471 | Ultra-sensitive, unbiased, high-throughput, biochemical CHANGE-seq genome-wide activity and gRNA sequencing assays for therapeutic genome editing INDs | 000 | 3 | NIH | 4/16/2025 | $479,100 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | K23HL166697 | School Readiness Intervention for Preschool Children with Sickle Cell Disease | 000 | 3 | NIH | 4/7/2025 | $167,146 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA266600 | EXPLORE AND TARGET THE EPIGENETIC VULNERABILITY OF PAX3-FOXO1-DRIVEN RHABDOMYOSARCOMA | 000 | 4 | NIH | 6/27/2025 | $691,425 |
| | 2025 | 2025 | ST JUDE CHILDREN'S RESEARCH HOSPITAL INC | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI165426 | Antibiotic tolerance: membraneless organelles and autolysin regulation | 000 | 4 | NIH | 3/28/2025 | $455,000 |
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