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 | Issue Date FY: 2022 ( Subtotal = $73,354,390 ) (Continued on the next page) |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM134358 | Gene regulation for stem cell differentiation | 001 | 4 | NIH | 5/27/2022 | $130,867 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM134358 | Gene regulation for stem cell differentiation | 000 | 4 | NIH | 5/27/2022 | $376,950 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | T32CA236748 | Childhood Hematological Malignancies Training Program | 000 | 4 | NIH | 7/29/2022 | $289,502 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01DK116835 | Improving HSC transplantation by defining novel regulators of engraftment | 001 | 4 | NIH | 3/29/2022 | $40,388 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01DK116835 | Improving HSC transplantation by defining novel regulators of engraftment | 000 | 4 | NIH | 12/28/2021 | $363,487 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA239630 | Neurostimulation in Adult Survivors of Childhood Leukemia | 000 | 4 | NIH | 4/26/2022 | $659,031 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01MH115058 | Role of the autophagy-inducing kinases ULK1/2 in ER export and protein trafficking | 000 | 5 | NIH | 4/21/2022 | $448,750 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | U24HG010135 | Clinical Pharmacogenetics Implementation Consortium (CPIC) | 000 | 5 | NIH | 7/15/2022 | $980,928 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA239689 | eHealth Intervention for Late Effects of Childhood Cancer | 001 | 3 | NIH | 5/4/2022 | $54,240 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA239689 | eHealth Intervention for Late Effects of Childhood Cancer | 000 | 3 | NIH | 3/22/2022 | $610,121 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI136514 | Decoding the interactions between T cell receptors and peptide-MHC | 000 | 5 | NIH | 5/20/2022 | $681,906 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01NS104029 | Siah2: an E3 ligase organizes polarity and cytoskeletal links in neuron migration | 000 | 5 | NIH | 7/1/2022 | $392,656 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA216391 | Discovery of Somatic Noncoding Variants that Serve as Drivers in Pediatric Cancers | 000 | 5 | NIH | 5/16/2022 | $552,832 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01NS108376 | Synthetic molecules to stimulate the expression of Frataxin to ameliorate Freidreichs Ataxin | 000 | 11 | NIH | 6/3/2022 | $608,525 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI140761 | Hippo signaling in stable regulatory activity and immune tolerance | 000 | 5 | NIH | 7/1/2022 | $448,750 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI131703 | Regulation of TH17 plasticity and stemness by mTORC1 | 000 | 5 | NIH | 1/25/2022 | $448,750 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01HL140295 | Clinical trial of AAV8-mediated FVIII gene transfer for hemophilia A | 001 | 5 | NIH | 6/13/2022 | $66,928 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01HL140295 | Clinical trial of AAV8-mediated FVIII gene transfer for hemophilia A | 000 | 5 | NIH | 11/26/2021 | $602,354 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R37AI044828 | Survival Function of the Fadd-Caspase-8-Flip Complex - MERIT Extension | 000 | 24 | NIH | 3/1/2022 | $455,000 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R37AI101935 | Inflammatory Caspases in Innate Immunity and Inflammation | 000 | 11 | NIH | 1/24/2022 | $455,000 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35CA197695 | Translating genomic discoveries to improved outcomes for high risk acute leukemia | 001 | 6 | NIH | 5/4/2022 | $86,161 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35CA197695 | Translating genomic discoveries to improved outcomes for high risk acute leukemia | 000 | 6 | NIH | 12/28/2021 | $969,300 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI124346 | Innate immune signaling and stress response | 000 | 7 | NIH | 2/16/2022 | $538,500 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA193478 | Web-based Physical Activity Intervention for Children with ALL | 000 | 6 | NIH | 6/27/2022 | $364,149 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35GM118041 | Regulation of xenobiotic receptors PXR and CAR, and CYP3A: implications in drug disposition | 002 | 7 | NIH | 7/1/2022 | -$68,534 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35GM118041 | Regulation of xenobiotic receptors PXR and CAR, and CYP3A: implications in drug disposition | 001 | 7 | NIH | 6/21/2022 | $113,409 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R35GM118041 | Regulation of xenobiotic receptors PXR and CAR, and CYP3A: implications in drug disposition | 000 | 7 | NIH | 3/22/2022 | $335,341 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI128756 | Bioactivities of pneumococcal cell wall in neuropathogenesis | 001 | 6 | NIH | 2/8/2022 | $455,000 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | U01CA195547 | The St. Jude Lifetime Cohort | 000 | 8 | NIH | 7/1/2022 | $870,269 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA194057 | Transporters and Medulloblastoma | 001 | 7 | NIH | 5/4/2022 | $32,524 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA194057 | Transporters and Medulloblastoma | 000 | 7 | NIH | 3/8/2022 | $365,848 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | T32AI106700 | Training in the Design and Development of Infectious Disease Therapeutics | 005 | 7 | NIH | 6/16/2022 | $3,823 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | T32AI106700 | Training in the Design and Development of Infectious Disease Therapeutics | 004 | 7 | NIH | 5/4/2022 | $219,416 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | UM1CA081457 | Pediatric Brain Tumor ConsortiumA multi-institutional consortium devoted to novel phase I and II clinical evaluations of experimental treatment approaches for pediatric CNS tumors. | 002 | 23 | NIH | 4/18/2022 | $3,440,662 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01DC012833 | Synaptic mechanisms of auditory memory | 000 | 10 | NIH | 8/11/2022 | $460,489 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | T32CA225590 | Training in Pediatric Cancer Survivorship Outcomes and Interventions | 001 | 5 | NIH | 5/27/2022 | $5,318 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | T32CA225590 | Training in Pediatric Cancer Survivorship Outcomes and Interventions | 000 | 5 | NIH | 3/17/2022 | $311,534 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01MH097742 | Towards understanding cellular mechanisms of positive symptoms of schizophrenia | 000 | 9 | NIH | 4/14/2022 | $470,098 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM112846 | The role of weak multivalent interactions and phase separation in SPOP tumor suppressor function | 001 | 8 | NIH | 8/2/2022 | $35,900 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM112846 | The role of weak multivalent interactions and phase separation in SPOP tumor suppressor function | 000 | 8 | NIH | 12/22/2021 | $323,100 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM034496 | Regulation of lipid metabolism in bacteria | 001 | 38 | NIH | 5/17/2022 | $72,301 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM034496 | Regulation of lipid metabolism in bacteria | 000 | 38 | NIH | 11/10/2021 | $650,723 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AI090810 | Development of Novel Proteins Synthesis Inhibitors for MDR Tuberculosis | 000 | 10 | NIH | 2/25/2022 | $747,745 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01AR056296 | Role of IL-1alpha signaling in inflammatory diseases and host defense | 000 | 15 | NIH | 8/10/2022 | $390,951 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | P01HL053749 | Lentiviral Gene Therapy for Sickle Cell Disease And Immunodeficiency Disorders | 000 | 25 | NIH | 7/13/2022 | $2,722,946 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01GM079238 | Imaging Protein Synthesis on the Ribosome using Single-Molecule FRET | 000 | 17 | NIH | 8/1/2022 | $462,213 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA113794 | The function of Snf5 (SMARCB1), an epigenetic tumor suppressor | 001 | 18 | NIH | 5/4/2022 | $33,881 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | R01CA113794 | The function of Snf5 (SMARCB1), an epigenetic tumor suppressor | 000 | 18 | NIH | 12/14/2021 | $381,158 |
| | 2022 | 2022 | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 262 DANNY THOMAS PL | MEMPHIS | TN | 38105-3678 | SHELBY | USA | U24CA055727 | Childhood Cancer Survivorship Study | 003 | 28 | NIH | 6/17/2022 | $0 |
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