| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2010 ( Subtotal = $1,367,400 ) |
| | 2010 | 2005 | ISIS PHARMACEUTICALS | 1896 Rutherford Rd | Carlsbad | CA | 92008-7326 | SAN DIEGO | USA | UC1AI067232 | PATHOGEN DIAGNOSTIC PRODUCTS--BIODEFENSE DEVELOPMENTS | 001 | 1 | NIH | 4/12/2010 | $1,367,400 |
|
| Issue Date FY: 2009 ( Subtotal = -$1,127,804 ) |
| | 2009 | 2009 | ISIS PHARMACEUTICALS | 1896 Rutherford Rd | Carlsbad | CA | 92008-7326 | SAN DIEGO | USA | R44GM076793 | CHEMICAL MODIFICATIONS TO IMPROVE RNAI DRUGS | 000 | 4 | NIH | 8/6/2009 | $463,365 |
| | 2009 | 2005 | ISIS PHARMACEUTICALS | 1896 Rutherford Rd | Carlsbad | CA | 92008-7326 | SAN DIEGO | USA | UC1AI067232 | PATHOGEN DIAGNOSTIC PRODUCTS--BIODEFENSE DEVELOPMENTS | 000 | 1 | NIH | 8/4/2009 | -$1,591,169 |
|
| Issue Date FY: 2008 ( Subtotal = $597,041 ) |
| | 2008 | 2008 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R44GM076793 | CHEMICAL MODIFICATIONS TO IMPROVE RNAI DRUGS | 000 | 3 | NIH | 7/28/2008 | $464,156 |
| | 2008 | 2008 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R43AI072802 | IDENTIFICATION OF AN INHIBITOR OF MICRORNA-122 IN LIVER | 000 | 2 | NIH | 9/4/2008 | $132,885 |
|
| Issue Date FY: 2007 ( Subtotal = $760,053 ) |
| | 2007 | 2007 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R44GM076793 | CHEMICAL MODIFICATIONS TO IMPROVE RNAI DRUGS | 000 | 2 | NIH | 9/28/2007 | $460,663 |
| | 2007 | 2007 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R43AI072802 | IDENTIFICATION OF AN INHIBITOR OF MICRORNA-122 IN LIVER | 000 | 1 | NIH | 7/30/2007 | $299,390 |
|
| Issue Date FY: 2006 ( Subtotal = $99,187 ) |
| | 2006 | 2006 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R43GM076793 | CHEMICAL MODIFICATION TO IMPROVE SIRNA PHARMACOKINETICS IN ANIMALS | 000 | 1 | NIH | 5/18/2006 | $99,187 |
|
| Issue Date FY: 2005 ( Subtotal = $1,036,103 ) |
| | 2005 | 2005 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R01CI000099 | AUTOMATED SIMULTANEOUS DETECTION OF BIOTERRORISM AGENTS | 000 | 3 | CDC | 8/31/2005 | $1,036,103 |
|
| Issue Date FY: 2004 ( Subtotal = $2,407,238 ) |
| | 2004 | 2004 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R43HL076946 | SINGLE WELL MPCR DONOR SCREEN TO ID BLOOD PATHOGENS | 000 | 1 | NIH | 3/29/2004 | $94,040 |
| | 2004 | 2004 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R01CI000099 | AUTOMATED SIMULTANEOUS DETECTION OF BIOTERRORISM AGENTS | 000 | 2 | CDC | 9/1/2004 | $2,313,198 |
|
| Issue Date FY: 2002 ( Subtotal = $375,000 ) |
| | 2002 | 2002 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R44AI045210 | ANTIMICROBIAL AGENTS DIRECTED AGAINST L11/23S RRNA | 000 | 3 | NIH | 8/26/2002 | $375,000 |
|
| Issue Date FY: 2001 ( Subtotal = $475,000 ) |
| | 2001 | 2001 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R41AI050406 | COMBINATORIAL CARBOHYDRATE LIBRARIES FOR DRUG DISCOVERY | 000 | 1 | NIH | 6/29/2001 | $100,000 |
| | 2001 | 2001 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008 | SAN DIEGO | USA | R44AI045210 | ANTIMICROBIAL AGENTS DIRECTED AGAINST L11/23S RRNA | 000 | 2 | NIH | 9/21/2001 | $375,000 |
|
| Issue Date FY: 2000 ( Subtotal = $223,990 ) |
| | 2000 | 2000 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43CA083601 | A NOVEL ANTICANCER STRATEGY | 000 | 1 | NIH | 2/23/2000 | $100,000 |
| | 2000 | 2000 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R41CA083543 | ORAL ANTISENSE THERAPY FOR CANCER | 000 | 1 | NIH | 6/28/2000 | $123,990 |
|
| Issue Date FY: 1999 ( Subtotal = $664,700 ) |
| | 1999 | 1999 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43AI045210 | L11/23S RRNA INTERACTION--ANTIMICROBIAL DRUG DEVELOPMENT | 000 | 1 | NIH | 2/18/1999 | $100,000 |
| | 1999 | 1999 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R41AI044515 | TARGETING 4.5S RNA ANTIMIRCOBIAL DRUG DISCOVERY | 000 | 1 | NIH | 9/30/1999 | $100,000 |
| | 1999 | 1999 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43GM058974 | ANTISENSE THERAPY USING NOVEL RNA MIMETICS | 000 | 1 | NIH | 1/14/1999 | $140,000 |
| | 1999 | 1999 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43AI044544 | DISRUPTION OF EUBACTERIAL 4.5S RNA -P48 COMPLEX | 000 | 1 | NIH | 9/3/1999 | $100,000 |
| | 1999 | 1999 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43GM060087 | OLIGONUCLEOTIDES FOR DIRECTED GENE KNOCKOUT | 000 | 1 | NIH | 7/23/1999 | $224,700 |
|
| Issue Date FY: 1998 ( Subtotal = $289,939 ) |
| | 1998 | 1998 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43CA074636 | UTILITY OF CARBOCYCLIC NUCLEOSIDES FOR ANTISENSE THERAPY | 001 | 1 | NIH | 6/3/1998 | $90,000 |
| | 1998 | 1998 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43AI043102 | TARGETING RHO--A TRANSCRIPTION TERMINATION FACTOR | 000 | 1 | NIH | 3/1/1998 | $100,000 |
| | 1998 | 1998 | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R41AI041775 | TARGETING AN ESSENTIAL METHYLASE IN PATHOGENIC BACTERIA | 000 | 1 | NIH | 7/22/1998 | $99,939 |
|
| Issue Date FY: 1997 ( Subtotal = $100,000 ) |
| | 1997 | | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43CA74636 | UTILITY OF CARBOCYCLIC NUCLEOSIDES FOR ANTISENSE THERAPY | 000 | 01 | NIH | 9/22/1997 | $100,000 |
|
| Issue Date FY: 1995 ( Subtotal = $580,704 ) |
| | 1995 | | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R41CA68790 | ANTISENSE INHIBITION OF MULTIDRUG RESISTANCE IN CANCER | 000 | 01 | NIH | 9/30/1995 | $99,865 |
| | 1995 | | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43CA52391 | OLIGONUCLEOTIDES AS INHIBITORS OF PAPILLOMAVIRUSES | 000 | 04 | NIH | 5/8/1995 | $127,758 |
| | 1995 | | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43AI30333 | 5' CAP--A NOVEL TARGET FOR ANTISENSE TECHNOLOGY | 000 | 03 | NIH | 1/12/1995 | $253,349 |
| | 1995 | | ISIS PHARMACEUTICALS | 2292 FARADAY AVE | CARLSBAD | CA | 92008-7326 | SAN DIEGO | USA | R43AR43034 | SYNTHESIS AND SELECTION OF PLA2 INHIBITORS | 000 | 01 | NIH | 4/28/1995 | $99,732 |
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