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| | |
 | Issue Date FY: 2025 ( Subtotal = $4,706,706 ) |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE033659 | Regulatory Mechanisms Controlling P. gingivalis Surface Structures | 000 | 2 | NIH | 3/19/2025 | $539,066 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE030646 | Intermittent fasting restores salivary gland function in Sjögren’s syndrome | 000 | 5 | NIH | 3/5/2025 | $425,363 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 000 | 3 | NIH | 3/5/2025 | $687,629 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE015654 | Genetic Regulatory Network in Craniofacial Development | 000 | 17 | NIH | 3/12/2025 | $762,445 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE016937 | A Foundation for the Oral Microbiome and Metagenome | 000 | 20 | NIH | 3/10/2025 | $1,080,257 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | F31DE033227 | Investigating the Function of Fimbriae-forming Lipoprotein in Porphyromonas gingivalis | 001 | 2 | NIH | 3/25/2025 | -$30,598 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE030943 | Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbes | 000 | 4 | NIH | 1/16/2025 | $472,217 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE031274 | Impact of Saccharibacteria and their bacterial hosts in Periodontal and Inflammatory Diseases | 000 | 4 | NIH | 12/20/2024 | $430,278 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | K99DE032048 | From Symbiosis to Dysbiosis and Back: The Impact of Pro-Inflammation and Pro-Resolution | 000 | 2 | NIH | 1/28/2025 | $164,700 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | F31DE033227 | Investigating the Function of Fimbriae-forming Lipoprotein in Porphyromonas gingivalis | 000 | 2 | NIH | 11/22/2024 | $43,963 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R25DE034582 | Forsyth Student Scholars Summer Internships in Oral Health Research | 000 | 1 | NIH | 12/11/2024 | $135,000 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01NS132387 | Integrated Wnt Signaling and Maternal Intervention of Neural Tube Defects | 001 | 2 | NIH | 1/27/2025 | $1 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | RM1DE034233 | Virtual Twin-Powered Rapid Development of Bioactive Multifunctional Dental Restoratives | 000 | 1 | NIH | 10/10/2024 | $0 |
| | 2025 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R13DE033284 | 2023 Forsyth Symposium: The Oral Microbiome: Past, Present, and Future | 000 | 1 | NIH | 1/29/2025 | -$3,615 |
|
| Issue Date FY: 2024 ( Subtotal = $12,420,064 ) (Continued on the next page) |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE023810 | Domestication and characterization of TM7-the most elusive oral phylum | 001 | 12 | NIH | 8/27/2024 | $587,904 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | K99DE032704 | The Role of CD4+ Memory T cell Subtypes in Periodontal Disease Recurrence | 000 | 2 | NIH | 8/1/2024 | $162,108 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033442 | Hydrolysis-resistant resin networks for durable and multifunctional dental restorations | 000 | 1 | NIH | 9/19/2024 | $499,440 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | K08DE033793 | Neuronal and Bacterial Driven Inflammation of the Dental Pulp in Molar Hypomineralization | 000 | 1 | NIH | 9/18/2024 | $152,680 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033659 | Regulatory Mechanisms Controlling P. gingivalis Surface Structures | 000 | 1 | NIH | 5/2/2024 | $553,165 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 002 | 2 | NIH | 8/5/2024 | $0 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 001 | 2 | NIH | 6/14/2024 | $61,743 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 000 | 2 | NIH | 3/27/2024 | $694,610 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE016937 | A Foundation for the Oral Microbiome and Metagenome | 001 | 19 | NIH | 6/18/2024 | $96,432 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE016937 | A Foundation for the Oral Microbiome and Metagenome | 000 | 19 | NIH | 4/19/2024 | $1,084,871 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030646 | Intermittent fasting restores salivary gland function in Sjögren’s syndrome | 001 | 4 | NIH | 6/18/2024 | $37,810 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030646 | Intermittent fasting restores salivary gland function in Sjögren’s syndrome | 000 | 4 | NIH | 2/9/2024 | $425,363 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | K99DE032048 | From Symbiosis to Dysbiosis and Back: The Impact of Pro-Inflammation and Pro-Resolution | 000 | 1 | NIH | 2/6/2024 | $164,700 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01NS132387 | Integrated Wnt Signaling and Maternal Intervention of Neural Tube Defects | 002 | 2 | NIH | 4/18/2024 | $736,302 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R56DE033090 | Mechanism of lysyl oxidase propeptide in oral squamous cell carcinoma microenvironments | 000 | 1 | NIH | 9/10/2024 | $612,048 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R56AI181002 | Gut Microbiome and Salivary Gland Function: Protective Actions & Key Players | 001 | 1 | NIH | 6/26/2024 | $40,001 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R56AI181002 | Gut Microbiome and Salivary Gland Function: Protective Actions & Key Players | 000 | 1 | NIH | 1/9/2024 | $359,999 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE031274 | Impact of Saccharibacteria and their bacterial hosts in Periodontal and Inflammatory Diseases | 001 | 3 | NIH | 6/18/2024 | $39,118 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE031274 | Impact of Saccharibacteria and their bacterial hosts in Periodontal and Inflammatory Diseases | 000 | 3 | NIH | 12/20/2023 | $440,063 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | K99DE033794 | Differentiation of Microbe-microbe Interactions at Single-cell Level Through Unconventional Utilization of Expansion Microscopy | 000 | 1 | NIH | 6/10/2024 | $162,216 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | RM1DE034233 | Virtual Twin-Powered Rapid Development of Bioactive Multifunctional Dental Restoratives | 000 | 1 | NIH | 9/18/2024 | $1,297,941 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033013 | Nonclassical β-catenin signaling in odontogenesis | 001 | 2 | NIH | 6/19/2024 | $43,356 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033013 | Nonclassical β-catenin signaling in odontogenesis | 000 | 2 | NIH | 4/18/2024 | $487,755 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030136 | Metapangenomics of the Oral Microbiome | 000 | 4 | NIH | 6/25/2024 | $588,140 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE029479 | Preventing dental caries through targeted treatment of acid-producing bacteria | 000 | 4 | NIH | 8/1/2024 | $681,995 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030943 | Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbes | 001 | 3 | NIH | 6/18/2024 | $39,298 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030943 | Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbes | 000 | 3 | NIH | 1/24/2024 | $442,083 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R90DE027638 | Forsyth Training in Oral Health Research | 000 | 8 | NIH | 6/28/2024 | $118,483 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | T90DE026110 | Forsyth Training in Oral Health Research | 001 | 8 | NIH | 6/28/2024 | $378,938 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE022586 | Spatial Organization of the Oral Microbiome | 002 | 13 | NIH | 8/2/2024 | $745,959 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE024580 | L-Arg availability affects the physiological state of porphyromonas gingivalis. | 000 | 10 | NIH | 6/28/2024 | $393,590 |
| | 2024 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE023810 | Domestication and characterization of TM7-the most elusive oral phylum | 000 | 11 | NIH | 8/20/2024 | $0 |
| | 2024 | 2023 | FORSYTH DENTAL INFIRMARY FOR CHILDREN | 245 FIRST ST | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE022586 | Spatial Organization of the Oral Microbiome | 000 | 12 | NIH | 10/10/2023 | $0 |
| | 2024 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | S10OD034405 | Spectral Confocal Imaging Instrumentation for Forsyth Advanced Microscopy Core | 000 | 1 | NIH | 8/28/2024 | $0 |
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