| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2026 ( Subtotal = $419,488 ) |
| | 2026 | 2026 | ADA FORSYTH INSTITUTE, INC. | 100 CHESTNUT ST FL 4 | SOMERVILLE | MA | 02143-2186 | MIDDLESEX | USA | R01DE031274 | Impact of Saccharibacteria and their bacterial hosts in Periodontal and Inflammatory Diseases | 000 | 5 | NIH | 12/1/2025 | $419,488 |
|
| Issue Date FY: 2025 ( Subtotal = $12,516,060 ) |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | K08DE033793 | Neuronal and Bacterial Driven Inflammation of the Dental Pulp in Molar Hypomineralization | 001 | 2 | NIH | 8/12/2025 | $610,718 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE030943 | Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbes | 000 | 4 | NIH | 1/16/2025 | $472,217 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE031274 | Impact of Saccharibacteria and their bacterial hosts in Periodontal and Inflammatory Diseases | 001 | 4 | NIH | 5/6/2025 | $47,809 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE031274 | Impact of Saccharibacteria and their bacterial hosts in Periodontal and Inflammatory Diseases | 000 | 4 | NIH | 12/20/2024 | $430,278 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | K99DE032048 | From Symbiosis to Dysbiosis and Back: The Impact of Pro-Inflammation and Pro-Resolution | 000 | 2 | NIH | 1/28/2025 | $164,700 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01NS132387 | Integrated Wnt Signaling and Maternal Intervention of Neural Tube Defects | 002 | 3 | NIH | 4/17/2025 | $759,076 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE033659 | Regulatory Mechanisms Controlling P. gingivalis Surface Structures | 000 | 2 | NIH | 3/19/2025 | $539,066 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE033659 | Regulatory Mechanisms Controlling P. gingivalis Surface Structures | 001 | 2 | NIH | 5/9/2025 | $59,894 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE015654 | Genetic Regulatory Network in Craniofacial Development | 000 | 17 | NIH | 3/12/2025 | $762,445 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R03DE034509 | Mechanistic investigation of multispecies interactions in clear aligner induced periodontal inflammation | 000 | 1 | NIH | 7/9/2025 | $398,000 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE030646 | Intermittent fasting restores salivary gland function in Sjögren’s syndrome | 001 | 5 | NIH | 5/7/2025 | $47,262 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE030646 | Intermittent fasting restores salivary gland function in Sjögren’s syndrome | 000 | 5 | NIH | 3/5/2025 | $425,363 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 001 | 3 | NIH | 5/8/2025 | $76,403 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 000 | 3 | NIH | 3/5/2025 | $687,629 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE016937 | A Foundation for the Oral Microbiome and Metagenome | 001 | 20 | NIH | 5/8/2025 | $120,029 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE016937 | A Foundation for the Oral Microbiome and Metagenome | 000 | 20 | NIH | 3/10/2025 | $1,080,257 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | RM1DE034233 | Virtual Twin-Powered Rapid Development of Bioactive Multifunctional Dental Restoratives | 001 | 2 | NIH | 7/1/2025 | $1,241,351 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | K99DE033794 | Differentiation of Microbe-microbe Interactions at Single-cell Level Through Unconventional Utilization of Expansion Microscopy | 000 | 2 | NIH | 5/27/2025 | $162,216 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE033013 | Nonclassical β-catenin signaling in odontogenesis | 001 | 3 | NIH | 5/8/2025 | $54,196 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE033013 | Nonclassical β-catenin signaling in odontogenesis | 000 | 3 | NIH | 4/4/2025 | $487,755 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | F31DE033227 | Investigating the Function of Fimbriae-forming Lipoprotein in Porphyromonas gingivalis | 000 | 2 | NIH | 11/22/2024 | $43,963 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | F31DE033227 | Investigating the Function of Fimbriae-forming Lipoprotein in Porphyromonas gingivalis | 001 | 2 | NIH | 3/25/2025 | -$30,598 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R21DE034091 | Cellular senescence contributes to salivary gland dysfunction in Sjögren’s syndrome | 000 | 1 | NIH | 4/28/2025 | $248,750 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE029479 | Preventing dental caries through targeted treatment of acid-producing bacteria | 000 | 5 | NIH | 7/25/2025 | $677,054 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE030136 | Metapangenomics of the Oral Microbiome | 000 | 5 | NIH | 5/22/2025 | $596,768 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R90DE027638 | Forsyth Training in Oral Health Research | 000 | 9 | NIH | 6/30/2025 | $115,387 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | T90DE026110 | Forsyth Training in Oral Health Research | 000 | 9 | NIH | 6/30/2025 | $385,290 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE023810 | Domestication and characterization of TM7-the most elusive oral phylum | 002 | 13 | NIH | 7/11/2025 | $563,154 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE022586 | Spatial Organization of the Oral Microbiome | 000 | 14 | NIH | 7/11/2025 | $732,837 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R25DE034582 | Forsyth Student Scholars Summer Internships in Oral Health Research | 000 | 1 | NIH | 12/11/2024 | $135,000 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE030943 | Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbes | 001 | 4 | NIH | 5/7/2025 | $52,468 |
| | 2025 | 2025 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE033442 | Hydrolysis-resistant resin networks for durable and multifunctional dental restorations | 000 | 2 | NIH | 7/1/2025 | $459,595 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 100 CHESTNUT ST FL 4 | SOMERVILLE | MA | 02143-2186 | MIDDLESEX | USA | R56AI181002 | Gut Microbiome and Salivary Gland Function: Protective Actions & Key Players | 000 | 1 | NIH | 12/10/2024 | $0 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01NS132387 | Integrated Wnt Signaling and Maternal Intervention of Neural Tube Defects | 001 | 2 | NIH | 1/27/2025 | $1 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | RM1DE034233 | Virtual Twin-Powered Rapid Development of Bioactive Multifunctional Dental Restoratives | 000 | 1 | NIH | 10/10/2024 | $0 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE023810 | Domestication and characterization of TM7-the most elusive oral phylum | 001 | 12 | NIH | 4/7/2025 | $102,526 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | K99DE032704 | The Role of CD4+ Memory T cell Subtypes in Periodontal Disease Recurrence | 001 | 2 | NIH | 6/30/2025 | -$86,658 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | K99DE032704 | The Role of CD4+ Memory T cell Subtypes in Periodontal Disease Recurrence | 000 | 2 | NIH | 4/9/2025 | $0 |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | K08DE033793 | Neuronal and Bacterial Driven Inflammation of the Dental Pulp in Molar Hypomineralization | 000 | 1 | NIH | 8/12/2025 | $0 |
| | 2025 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R13DE033284 | 2023 Forsyth Symposium: The Oral Microbiome: Past, Present, and Future | 000 | 1 | NIH | 1/29/2025 | -$3,615 |
| | 2025 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE015654 | Genetic Regulatory Network in Craniofacial Development | 001 | 16 | NIH | 6/11/2025 | $0 |
| | 2025 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE023810 | Domestication and characterization of TM7-the most elusive oral phylum | 000 | 11 | NIH | 4/7/2025 | -$102,526 |
| | 2025 | 2022 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01NS102261 | Surface ectodermal mechanism and maternal intervention of neural tube defects | 001 | 6 | NIH | 8/7/2025 | $0 |
|
| Issue Date FY: 2024 ( Subtotal = $12,420,064 ) (Continued on the next page) |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 002 | 2 | NIH | 8/5/2024 | $0 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE016937 | A Foundation for the Oral Microbiome and Metagenome | 000 | 19 | NIH | 4/19/2024 | $1,084,871 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033659 | Regulatory Mechanisms Controlling P. gingivalis Surface Structures | 000 | 1 | NIH | 5/2/2024 | $553,165 |
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