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 | Issue Date FY: 2025 ( Subtotal = $0 ) |
| | 2025 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | RM1DE034233 | Virtual Twin-Powered Rapid Development of Bioactive Multifunctional Dental Restoratives | 000 | 1 | NIH | 10/10/2024 | $0 |
|
| Issue Date FY: 2024 ( Subtotal = $12,420,064 ) (Continued on the next page) |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R56AI181002 | Gut Microbiome and Salivary Gland Function: Protective Actions & Key Players | 001 | 1 | NIH | 6/26/2024 | $40,001 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01NS132387 | Integrated Wnt Signaling and Maternal Intervention of Neural Tube Defects | 002 | 2 | NIH | 4/18/2024 | $736,302 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R90DE027638 | Forsyth Training in Oral Health Research | 000 | 8 | NIH | 6/28/2024 | $118,483 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE016937 | A Foundation for the Oral Microbiome and Metagenome | 000 | 19 | NIH | 4/19/2024 | $1,084,871 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE016937 | A Foundation for the Oral Microbiome and Metagenome | 001 | 19 | NIH | 6/18/2024 | $96,432 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 002 | 2 | NIH | 8/5/2024 | $0 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 001 | 2 | NIH | 6/14/2024 | $61,743 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R56DE033090 | Mechanism of lysyl oxidase propeptide in oral squamous cell carcinoma microenvironments | 000 | 1 | NIH | 9/10/2024 | $612,048 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE032834 | Caries resistance mechanisms in high-risk Indigenous children | 000 | 2 | NIH | 3/27/2024 | $694,610 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | RM1DE034233 | Virtual Twin-Powered Rapid Development of Bioactive Multifunctional Dental Restoratives | 000 | 1 | NIH | 9/18/2024 | $1,297,941 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | T90DE026110 | Forsyth Training in Oral Health Research | 001 | 8 | NIH | 6/28/2024 | $378,938 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE029479 | Preventing dental caries through targeted treatment of acid-producing bacteria | 000 | 4 | NIH | 8/1/2024 | $681,995 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033013 | Nonclassical β-catenin signaling in odontogenesis | 001 | 2 | NIH | 6/19/2024 | $43,356 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | K99DE032704 | The Role of CD4+ Memory T cell Subtypes in Periodontal Disease Recurrence | 000 | 2 | NIH | 8/1/2024 | $162,108 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030136 | Metapangenomics of the Oral Microbiome | 000 | 4 | NIH | 6/25/2024 | $588,140 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030943 | Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbes | 001 | 3 | NIH | 6/18/2024 | $39,298 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE031274 | Impact of Saccharibacteria and their bacterial hosts in Periodontal and Inflammatory Diseases | 001 | 3 | NIH | 6/18/2024 | $39,118 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE022586 | Spatial Organization of the Oral Microbiome | 002 | 13 | NIH | 8/2/2024 | $745,959 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033013 | Nonclassical β-catenin signaling in odontogenesis | 000 | 2 | NIH | 4/18/2024 | $487,755 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033659 | Regulatory Mechanisms Controlling P. gingivalis Surface Structures | 000 | 1 | NIH | 5/2/2024 | $553,165 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | K99DE032048 | From Symbiosis to Dysbiosis and Back: The Impact of Pro-Inflammation and Pro-Resolution | 000 | 1 | NIH | 2/6/2024 | $164,700 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030943 | Host tRNA-derived small RNAs (tsRNAs) mediate interactions between host and oral microbes | 000 | 3 | NIH | 1/24/2024 | $442,083 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE031274 | Impact of Saccharibacteria and their bacterial hosts in Periodontal and Inflammatory Diseases | 000 | 3 | NIH | 12/20/2023 | $440,063 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | K99DE033794 | Differentiation of Microbe-microbe Interactions at Single-cell Level Through Unconventional Utilization of Expansion Microscopy | 000 | 1 | NIH | 6/10/2024 | $162,216 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE023810 | Domestication and characterization of TM7-the most elusive oral phylum | 001 | 12 | NIH | 8/27/2024 | $587,904 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE024580 | L-Arg availability affects the physiological state of porphyromonas gingivalis. | 000 | 10 | NIH | 6/28/2024 | $393,590 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030646 | Intermittent fasting restores salivary gland function in Sjögren’s syndrome | 001 | 4 | NIH | 6/18/2024 | $37,810 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE033442 | Hydrolysis-resistant resin networks for durable and multifunctional dental restorations | 000 | 1 | NIH | 9/19/2024 | $499,440 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE030646 | Intermittent fasting restores salivary gland function in Sjögren’s syndrome | 000 | 4 | NIH | 2/9/2024 | $425,363 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R56AI181002 | Gut Microbiome and Salivary Gland Function: Protective Actions & Key Players | 000 | 1 | NIH | 1/9/2024 | $359,999 |
| | 2024 | 2024 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | K08DE033793 | Neuronal and Bacterial Driven Inflammation of the Dental Pulp in Molar Hypomineralization | 000 | 1 | NIH | 9/18/2024 | $152,680 |
| | 2024 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE022586 | Spatial Organization of the Oral Microbiome | 004 | 12 | NIH | 9/27/2024 | $162,823 |
| | 2024 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | S10OD034405 | Spectral Confocal Imaging Instrumentation for Forsyth Advanced Microscopy Core | 000 | 1 | NIH | 8/28/2024 | $0 |
| | 2024 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | T90DE026110 | Forsyth Training in Oral Health Research | 000 | 7 | NIH | 3/6/2024 | -$50,000 |
| | 2024 | 2023 | FORSYTH DENTAL INFIRMARY FOR CHILDREN | 245 FIRST ST | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE022586 | Spatial Organization of the Oral Microbiome | 001 | 12 | NIH | 11/7/2023 | $0 |
| | 2024 | 2023 | FORSYTH DENTAL INFIRMARY FOR CHILDREN | 245 FIRST ST | CAMBRIDGE | MA | 02142-1200 | MIDDLESEX | USA | R01DE022586 | Spatial Organization of the Oral Microbiome | 000 | 12 | NIH | 10/10/2023 | $0 |
| | 2024 | 2023 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE023810 | Domestication and characterization of TM7-the most elusive oral phylum | 000 | 11 | NIH | 8/20/2024 | $0 |
| | 2024 | 2022 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R03DE030209 | Pathogenic role of peroxisome proliferator-activated receptor alpha in periodontitis | 000 | 2 | NIH | 8/26/2024 | $0 |
| | 2024 | 2022 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R21DE030619 | Identification and Characterization of Endogenous Dental Pulp Stem Cells | 000 | 3 | NIH | 9/4/2024 | $0 |
| | 2024 | 2022 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE022586 | Spatial Organization of the Oral Microbiome | 003 | 11 | NIH | 9/27/2024 | -$162,823 |
| | 2024 | 2022 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01NS102261 | Surface ectodermal mechanism and maternal intervention of neural tube defects | 002 | 6 | NIH | 7/1/2024 | $341,953 |
| | 2024 | 2022 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R00DE027719 | Molecular and pathogenic study of an oral TM7 strain, the first cultivated ultra-small bacterium | 000 | 5 | NIH | 12/12/2023 | $0 |
| | 2024 | 2022 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R21AR077260 | Osteoblast Dopamine Receptor Mediates Diabetic Bone Disease | 000 | 2 | NIH | 6/24/2024 | $0 |
| | 2024 | 2022 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R01DE026936 | Stem cells for craniofacial bone repair and regeneration | 000 | 5 | NIH | 6/7/2024 | $0 |
| | 2024 | 2021 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R21DE029925 | pH-sensitive materials responding to metabolic activities of cariogenic plaque | 000 | 2 | NIH | 5/28/2024 | $0 |
| | 2024 | 2021 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R21DE029903 | A biomimetic strategy to treat enamel loss | 000 | 2 | NIH | 5/28/2024 | $0 |
| | 2024 | 2021 | ADA FORSYTH INSTITUTE, INC. | 245 1ST ST 17TH FLOOR | CAMBRIDGE | MA | 02142-1292 | MIDDLESEX | USA | R03DE029273 | What gives the dentin-enamel junction strength? Structural and mechanical function of collagen and amelogenin. | 000 | 2 | NIH | 1/16/2024 | $0 |
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