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 | Issue Date FY: 2026 ( Subtotal = -$1,268,217 ) |
| | 2026 | 2026 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R21AI182870 | Novel translational strategies to combat group B streptococcus infections | 000 | 2 | NIH | 11/26/2025 | $201,875 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI106200 | Control of dysfunctional Tregs | 000 | 10 | NIH | 11/4/2025 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01NS121405 | S100A4 mediated immune suppression in GBM | 000 | 5 | NIH | 12/11/2025 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AG077685 | Central and peripheral immune cross-talk in Alzheimer's disease and their modulation by a novel immunotherapy | 000 | 3 | NIH | 10/21/2025 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01EY026156 | The Impact of Sleep on Network Coding and Perceptual Performance | 000 | 9 | NIH | 11/25/2025 | $0 |
| | 2026 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01EB035545 | Artificial intelligence-integrated mechanistic modeling for rational design of nanoparticles to improve organ targeting and safety | 000 | 2 | NIH | 12/5/2025 | -$418,254 |
| | 2026 | 2024 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA244344 | Novel Targeted Therapeutics for Breast Cancer | 000 | 5 | NIH | 12/2/2025 | -$6,025 |
| | 2026 | 2024 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01NS118584 | Age-related TDP-43 neuropathology: using disease-driving mechanisms to guide classification | 000 | 2 | NIH | 10/1/2025 | -$941,155 |
| | 2026 | 2024 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R37CA251318 | P38 MAPK is a molecular switch that controls the acquired resistance in adoptive cell therapy | 000 | 6 | NIH | 11/20/2025 | -$77,934 |
| | 2026 | 2023 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA239255 | Role of tumor microenvironment-derived cholesterol in CD8+ T-cell exhaustion | 000 | 5 | NIH | 12/8/2025 | -$10,691 |
| | 2026 | 2022 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R21NS125509 | Methods and devices to assist and improve cerebrospinal fluid drainage | 000 | 1 | NIH | 11/25/2025 | $0 |
| | 2026 | 2021 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01DE027251 | Learning-Based Approach for Personalized Craniomaxillofacial Surgical Planning | 000 | 5 | NIH | 11/21/2025 | -$16,032 |
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| Issue Date FY: 2025 ( Subtotal = $52,762,575 ) (Continued on the next page) |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI173138 | Clinical Impact of the Cefazolin Inoculum Effect | 000 | 3 | NIH | 9/3/2025 | $425,805 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI173138 | Clinical Impact of the Cefazolin Inoculum Effect | 002 | 3 | NIH | 9/5/2025 | $161,779 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01NS129788 | Relationship of the Human Astrocyte Matrisome with Synaptic Networks | 000 | 4 | NIH | 8/4/2025 | $439,740 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL158703 | Mechanisms driving cardiac dysfunction in Autosomal Dominant Polycystic Kidney Disease | 000 | 4 | NIH | 4/10/2025 | $403,750 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01NS124813 | Pathogenesis in Segmental Demyelination | 000 | 3 | NIH | 6/4/2025 | $401,211 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA280746 | Targeting phenethyl isothiocyanate to mitochondria in lung carcinogenesis | 001 | 2 | NIH | 6/12/2025 | $62,546 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA280746 | Targeting phenethyl isothiocyanate to mitochondria in lung carcinogenesis | 000 | 2 | NIH | 1/8/2025 | $562,925 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL168277 | Cardiac Autonomic Activation In Atrial Fibrillation Triggers And Substrate | 001 | 3 | NIH | 2/28/2025 | $722,692 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL168277 | Cardiac Autonomic Activation In Atrial Fibrillation Triggers And Substrate | 002 | 3 | NIH | 8/19/2025 | $80,299 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01NS129720 | “Pharmacologic targeting of NR4A1 and NR4A2 to activate glioblastoma treatment response” | 000 | 3 | NIH | 8/8/2025 | $554,314 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R35GM150460 | Landscapes for Cell State Transition Leveraging by Single-Cell Multi-Omics | 000 | 3 | NIH | 8/15/2025 | $403,739 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI167659 | Long-acting multi prevention implant for 2-year contraception and HIV PrEP | 000 | 3 | NIH | 3/28/2025 | $817,162 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL174587 | Advancing Endovascular PAD Treatment: Overcoming Critical Knowledge Gaps with MRI-histology | 000 | 2 | NIH | 5/7/2025 | $719,088 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | U54CA274375 | The stromal microenvironment as a co-organizer of bladder carcinogenesis and progression | 003 | 4 | NIH | 9/18/2025 | $1,646,006 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA271682 | Validation of a novel 3D culture platform for TNBC treatment selection | 002 | 4 | NIH | 9/11/2025 | $1,198,662 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI176558 | Regulation of Cell Death in HIV Reservoirs | 000 | 3 | NIH | 2/28/2025 | $575,980 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01DK133610 | Vascularized NICHE with local immunosuppression for cell replacement for Type 1 diabetes | 000 | 4 | NIH | 6/9/2025 | $754,051 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI155488 | Studies of a new checkpoint regulator in the control of intestinal inflammation | 000 | 5 | NIH | 7/21/2025 | $403,750 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | T32NS126115 | Training in Neural Control of organ Degeneration and Regeneration (NeuralCODR) | 001 | 4 | NIH | 8/15/2025 | $29,710 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | T32NS126115 | Training in Neural Control of organ Degeneration and Regeneration (NeuralCODR) | 000 | 4 | NIH | 7/25/2025 | $370,868 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA269835 | Mechanisms of STING in malignant progression and therapy of CLL. | 001 | 3 | NIH | 8/22/2025 | $49,214 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA269835 | Mechanisms of STING in malignant progression and therapy of CLL. | 000 | 3 | NIH | 1/24/2025 | $442,928 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01DK132104 | Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetes | 000 | 4 | NIH | 4/28/2025 | $697,245 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA255609 | Targeting tumor repopulation and the immune microenvironment to overcome chemoresistance | 000 | 6 | NIH | 8/1/2025 | $452,797 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI165372 | Ultra-long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure | 001 | 4 | NIH | 8/5/2025 | $1,801,942 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI162748 | Molecular Mechanism of Virulence Regulation in Streptococcus Pyogenes | 000 | 5 | NIH | 8/7/2025 | $563,732 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG071496 | Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer's Disease | 001 | 5 | NIH | 6/10/2025 | $63,265 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG071496 | Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer's Disease | 000 | 5 | NIH | 4/1/2025 | $711,722 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA253865 | Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer | 001 | 5 | NIH | 5/22/2025 | $39,803 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA253865 | Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer | 000 | 5 | NIH | 3/5/2025 | $358,221 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI146048 | Molecular mechanism of streptococcal adaptation to host nutritional defenses | 000 | 6 | NIH | 1/17/2025 | $173,799 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA248111 | Eradication of Escaped Variant Tumor Cells for Cancer Immunotherapy | 000 | 6 | NIH | 8/1/2025 | $388,825 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | P01AI152999 | Dynamics of Colonization and Infection by Multidrug-resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE) | 000 | 5 | NIH | 8/12/2025 | $2,377,848 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | K24AI121296 | POR and Training Program on Multidrug-Resistant Organisms | 000 | 10 | NIH | 7/16/2025 | $126,566 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01EY026156 | The Impact of Sleep on Network Coding and Perceptual Performance | 000 | 9 | NIH | 1/8/2025 | $475,319 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA163910 | Targeting ER stress response in B-cell chronic lymphocytic leukemia | 000 | 12 | NIH | 1/22/2025 | $403,750 |
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