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 | Issue Date FY: 2025 ( Subtotal = $30,798,446 ) (Continued on the next page) |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL171150 | Sudden Death Risk Assessment and Mechanistic Insights in Arrhythmic Mitral Valve Prolapse Using Cardiac MRI and Circulating Proteomic Biomarkers | 000 | 2 | NIH | 6/27/2025 | $1,442,069 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA294584 | Mechanisms of JAG1-mediated immune suppression in the pancreatic cancer microenvironment | 000 | 2 | NIH | 6/9/2025 | $657,074 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA285209 | Tumor-specific CD8+ Tc9 cells activate host CD4+ T cells to control antigen-lost tumors | 001 | 2 | NIH | 6/6/2025 | $48,987 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA285209 | Tumor-specific CD8+ Tc9 cells activate host CD4+ T cells to control antigen-lost tumors | 000 | 2 | NIH | 11/19/2024 | $440,870 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R61CA278458 | A multiplexed high-throughput platform to report pharmacologic alteration of cancer stem cell membrane potential and cell cycle state | 001 | 2 | NIH | 5/23/2025 | $22,333 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R61CA278458 | A multiplexed high-throughput platform to report pharmacologic alteration of cancer stem cell membrane potential and cell cycle state | 000 | 2 | NIH | 4/7/2025 | $200,994 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | K23AI185174 | Pathogen and patient determinants of Candida gut colonization in critically ill patients | 000 | 2 | NIH | 5/16/2025 | $194,036 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA284315 | Dual targeting of PI3K and NOS pathways in Metaplastic BreastCancer (MBC) | 000 | 3 | NIH | 6/27/2025 | $654,245 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA282099 | Novel mechanism of induction of tumor pyroptosis by IL-9-secreting Tc9 cells | 000 | 3 | NIH | 6/18/2025 | $473,214 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | T32AI179595 | Antimicrobial Resistance Training Program in the Texas Medical Center (AMR-TPT) | 000 | 2 | NIH | 4/18/2025 | $341,711 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA285203 | Exploring the role and potential of anti-viral drugs to sensitize cancer cells to chemotherapy | 000 | 2 | NIH | 7/1/2025 | $472,355 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA283580 | Novel gene delivery to modulate the tumor microenvironment and antigen-specific antitumor immunity | 000 | 2 | NIH | 6/12/2025 | $610,783 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI106200 | Control of dysfunctional Tregs | 000 | 10 | NIH | 1/15/2025 | $469,966 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288884 | Functional roles of mTOR in tumor persistence | 001 | 2 | NIH | 5/22/2025 | $40,109 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288884 | Functional roles of mTOR in tumor persistence | 000 | 2 | NIH | 4/17/2025 | $360,978 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL158703 | Mechanisms driving cardiac dysfunction in Autosomal Dominant Polycystic Kidney Disease | 000 | 4 | NIH | 4/10/2025 | $403,750 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01NS124813 | Pathogenesis in Segmental Demyelination | 000 | 3 | NIH | 6/4/2025 | $401,211 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA280746 | Targeting phenethyl isothiocyanate to mitochondria in lung carcinogenesis | 001 | 2 | NIH | 6/12/2025 | $62,546 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA280746 | Targeting phenethyl isothiocyanate to mitochondria in lung carcinogenesis | 000 | 2 | NIH | 1/8/2025 | $562,925 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG077685 | Central and peripheral immune cross-talk in Alzheimer's disease and their modulation by a novel immunotherapy | 000 | 3 | NIH | 2/14/2025 | $592,201 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R21AI190338 | Mechanisms of Resistance and Clinical Outcomes of non-Carbapenemase Producing Carbapenem-Resistant Klebsiella pneumoniae Infections | 000 | 1 | NIH | 2/28/2025 | $259,461 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL168277 | Cardiac Autonomic Activation In Atrial Fibrillation Triggers And Substrate | 001 | 3 | NIH | 2/28/2025 | $722,692 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI167659 | Long-acting multi prevention implant for 2-year contraception and HIV PrEP | 000 | 3 | NIH | 3/28/2025 | $817,162 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL174587 | Advancing Endovascular PAD Treatment: Overcoming Critical Knowledge Gaps with MRI-histology | 000 | 2 | NIH | 5/7/2025 | $719,088 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01DK133610 | Vascularized NICHE with local immunosuppression for cell replacement for Type 1 diabetes | 000 | 4 | NIH | 6/9/2025 | $754,051 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI176558 | Regulation of Cell Death in HIV Reservoirs | 000 | 3 | NIH | 2/28/2025 | $575,980 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI155488 | Studies of a new checkpoint regulator in the control of intestinal inflammation | 000 | 5 | NIH | 7/21/2025 | $403,750 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R13NS141592 | 2025 Patrica Levy Zusman International Workshop on Neuroregeneration | 000 | 1 | NIH | 2/28/2025 | $14,000 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | T32NS126115 | Training in Neural Control of organ Degeneration and Regeneration (NeuralCODR) | 000 | 4 | NIH | 7/25/2025 | $370,868 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01DK132104 | Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetes | 000 | 4 | NIH | 4/28/2025 | $697,245 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA269835 | Mechanisms of STING in malignant progression and therapy of CLL. | 000 | 3 | NIH | 1/24/2025 | $442,928 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG071496 | Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer's Disease | 001 | 5 | NIH | 6/10/2025 | $63,265 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG071496 | Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer's Disease | 000 | 5 | NIH | 4/1/2025 | $711,722 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA253865 | Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer | 001 | 5 | NIH | 5/22/2025 | $39,803 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA253865 | Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer | 000 | 5 | NIH | 3/5/2025 | $358,221 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI146048 | Molecular mechanism of streptococcal adaptation to host nutritional defenses | 000 | 6 | NIH | 1/17/2025 | $173,799 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL163535 | Human Atherogenesis with Underlying Dysfunctional HDL-Free Cholesterol | 000 | 3 | NIH | 3/11/2025 | $673,341 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01EY026156 | The Impact of Sleep on Network Coding and Perceptual Performance | 000 | 9 | NIH | 1/8/2025 | $475,319 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | K24AI121296 | POR and Training Program on Multidrug-Resistant Organisms | 000 | 10 | NIH | 7/16/2025 | $126,566 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA175397 | Distinct Tumor and Metastatic Collagen Microenvironments: Divergent Targeting Approaches | 004 | 11 | NIH | 5/22/2025 | $385,560 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288403 | Decoupling acute toxicities and antitumor efficacy in adoptive cell therapy | 001 | 2 | NIH | 5/26/2025 | $59,380 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288403 | Decoupling acute toxicities and antitumor efficacy in adoptive cell therapy | 000 | 2 | NIH | 4/18/2025 | $534,430 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL177797 | Role of Cdk9 in the Pathogenesis of Pulmonary Fibrosis | 001 | 1 | NIH | 2/25/2025 | $0 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL177797 | Role of Cdk9 in the Pathogenesis of Pulmonary Fibrosis | 000 | 1 | NIH | 12/31/2024 | $705,334 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG080925 | Proteomics based mapping of cardiac extracellular matrix to define sex and age-dependent changes. | 007 | 4 | NIH | 7/22/2025 | $50,343 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG080925 | Proteomics based mapping of cardiac extracellular matrix to define sex and age-dependent changes. | 005 | 4 | NIH | 5/7/2025 | -$168,099 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG080925 | Proteomics based mapping of cardiac extracellular matrix to define sex and age-dependent changes. | 004 | 4 | NIH | 5/7/2025 | $168,099 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG080925 | Proteomics based mapping of cardiac extracellular matrix to define sex and age-dependent changes. | 002 | 4 | NIH | 3/27/2025 | $566,366 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288613 | Advancing Thyroid Cancer Diagnostics with AI-enhanced Multimodal Optical Histopathology | 000 | 1 | NIH | 12/25/2024 | $593,383 |
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