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 | Issue Date FY: 2026 ( Subtotal = $9,077,282 ) (Continued on the next page) |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI179616 | Modulation of chromatin dynamics to promote transplant survival | 000 | 3 | NIH | 12/29/2025 | $628,171 |
| | 2026 | 2026 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R21AI182870 | Novel translational strategies to combat group B streptococcus infections | 000 | 2 | NIH | 11/26/2025 | $201,875 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R21AI190338 | Mechanisms of Resistance and Clinical Outcomes of non-Carbapenemase Producing Carbapenem-Resistant Klebsiella pneumoniae Infections | 000 | 2 | NIH | 3/26/2026 | $164,100 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01NS140292 | DeepStroke+: An Advanced Mobile AI Diagnostic Tool for Fast and Precise Detection of Acute Strokes in Mobile Stroke Units, Emergency Rooms, and Telestroke Triage | 001 | 2 | NIH | 2/23/2026 | $59,440 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01NS140292 | DeepStroke+: An Advanced Mobile AI Diagnostic Tool for Fast and Precise Detection of Acute Strokes in Mobile Stroke Units, Emergency Rooms, and Telestroke Triage | 000 | 2 | NIH | 1/19/2026 | $534,966 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01HL177797 | Role of Cdk9 in the Pathogenesis of Pulmonary Fibrosis | 001 | 2 | NIH | 3/25/2026 | $20,681 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01HL177797 | Role of Cdk9 in the Pathogenesis of Pulmonary Fibrosis | 000 | 2 | NIH | 2/12/2026 | $654,870 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01HL168277 | Cardiac Autonomic Activation In Atrial Fibrillation Triggers And Substrate | 000 | 4 | NIH | 3/9/2026 | $762,842 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01HL163535 | Human Atherogenesis with Underlying Dysfunctional HDL-Free Cholesterol | 000 | 4 | NIH | 3/11/2026 | $710,747 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01DK134340 | A randomized, sham-controlled clinical trial evaluating individualized neuromodulation of cortical regions involved in neurogenic overactive bladder in Multiple Sclerosis | 000 | 4 | NIH | 12/17/2025 | $338,159 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA280746 | Targeting phenethyl isothiocyanate to mitochondria in lung carcinogenesis | 000 | 3 | NIH | 1/27/2026 | $592,923 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA288884 | Functional roles of mTOR in tumor persistence | 000 | 3 | NIH | 3/19/2026 | $401,087 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA288613 | Advancing Thyroid Cancer Diagnostics with AI-enhanced Multimodal Optical Histopathology | 000 | 2 | NIH | 2/2/2026 | $439,250 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA285209 | Tumor-specific CD8+ Tc9 cells activate host CD4+ T cells to control antigen-lost tumors | 000 | 3 | NIH | 1/12/2026 | $440,870 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA269835 | Mechanisms of STING in malignant progression and therapy of CLL. | 000 | 4 | NIH | 2/11/2026 | $442,928 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI195499 | The epigenetic regulation of alloimmune stem-like CD4+ T cells | 000 | 1 | NIH | 2/3/2026 | $491,663 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI190307 | Deciphering the activation mechanisms and immune functions of GSDMC | 000 | 1 | NIH | 3/27/2026 | $2,469,932 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | U01CA268813 | A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC) | 000 | 4 | NIH | 1/16/2026 | $305,910 |
| | 2026 | 2026 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI176558 | Regulation of Cell Death in HIV Reservoirs | 000 | 4 | NIH | 2/17/2026 | $593,795 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01NS121405 | S100A4 mediated immune suppression in GBM | 000 | 5 | NIH | 12/11/2025 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01MH127979 | Targeting the HIV-1 Reservoir in Myeloid Cells | 000 | 5 | NIH | 3/24/2026 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01EY026156 | The Impact of Sleep on Network Coding and Perceptual Performance | 000 | 9 | NIH | 11/25/2025 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01EB035545 | Artificial intelligence-integrated mechanistic modeling for rational design of nanoparticles to improve organ targeting and safety | 002 | 2 | NIH | 3/2/2026 | $0 |
| | 2026 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01EB035545 | Artificial intelligence-integrated mechanistic modeling for rational design of nanoparticles to improve organ targeting and safety | 000 | 2 | NIH | 12/5/2025 | -$418,254 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01DK132104 | Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetes | 000 | 4 | NIH | 3/4/2026 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA253865 | Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer | 000 | 5 | NIH | 12/31/2025 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI155488 | Studies of a new checkpoint regulator in the control of intestinal inflammation | 000 | 5 | NIH | 3/9/2026 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI146257 | Gut microbiome communication with the bone marrow regulates intestinal inflammation. | 000 | 6 | NIH | 1/5/2026 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI146048 | Molecular mechanism of streptococcal adaptation to host nutritional defenses | 000 | 6 | NIH | 3/5/2026 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI106200 | Control of dysfunctional Tregs | 000 | 10 | NIH | 11/4/2025 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AG077685 | Central and peripheral immune cross-talk in Alzheimer's disease and their modulation by a novel immunotherapy | 000 | 3 | NIH | 10/21/2025 | $0 |
| | 2026 | 2025 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AG071496 | Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer's Disease | 000 | 5 | NIH | 3/27/2026 | $0 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | U01CA244107 | Biophysical roles of pre-metastatic niche evolution on transport of circulating tumor cells | 000 | 5 | NIH | 1/29/2026 | $0 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R56AG085576 | Multi-omic integrative analysis of shared and distinct inflammation networks across neurodegenerative disorders | 000 | 1 | NIH | 1/2/2026 | $0 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R37CA251318 | P38 MAPK is a molecular switch that controls the acquired resistance in adoptive cell therapy | 000 | 6 | NIH | 11/20/2025 | -$77,934 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R21NS127229 | Patterned optogenetic neuromodulation to reprogram glioma stem cells | 000 | 1 | NIH | 2/6/2026 | $0 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R13DK138734 | Neurogenic Bladder Research Group (NBRG) symposium: Partnering with Engineering in Neurogenic Bladder Research | 000 | 1 | NIH | 3/5/2026 | -$1,941 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01NS118584 | Age-related TDP-43 neuropathology: using disease-driving mechanisms to guide classification | 000 | 2 | NIH | 10/1/2025 | -$941,155 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA271682 | Validation of a novel 3D culture platform for TNBC treatment selection | 000 | 3 | NIH | 1/16/2026 | $0 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA244344 | Novel Targeted Therapeutics for Breast Cancer | 000 | 5 | NIH | 12/2/2025 | -$6,025 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA237200 | Exploring the role of estrogen receptor beta in progression and metastasis ofInflammatory breast cancer | 000 | 6 | NIH | 4/2/2026 | $0 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI165372 | Ultra-long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure | 000 | 3 | NIH | 2/5/2026 | $0 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01AI175699 | Deep Learning Based Pharmacokinetic Model for Vancomycin | 000 | 2 | NIH | 3/31/2026 | $0 |
| | 2026 | 2024 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | DP2GM146320 | Necrotic survivors and plasma membrane integrity signaling | 001 | 3 | NIH | 3/3/2026 | $432,496 |
| | 2026 | 2023 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R21AR083189 | In situ and real-time readout of nuclear mechanotransduction via single cell mechanics and site-specific fluorescence reporting | 000 | 1 | NIH | 2/26/2026 | -$137,390 |
| | 2026 | 2023 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA239255 | Role of tumor microenvironment-derived cholesterol in CD8+ T-cell exhaustion | 000 | 5 | NIH | 12/8/2025 | -$10,691 |
| | 2026 | 2023 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA222959 | Mechanism of Intratumoral Transport of Particulate Drugs | 000 | 5 | NIH | 1/14/2026 | $0 |
| | 2026 | 2023 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R01CA232433 | Chemoprevention of lung cancer by targeting lonidamine to mitochondria | 000 | 5 | NIH | 1/12/2026 | $0 |
| | 2026 | 2022 | THE METHODIST HOSPITAL RESEARCH INSTITUTE | 6565 FANNIN ST STE D200 | HOUSTON | TX | 77030-2703 | HARRIS | USA | R21NS125509 | Methods and devices to assist and improve cerebrospinal fluid drainage | 000 | 1 | NIH | 11/25/2025 | $0 |
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