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 | Issue Date FY: 2025 ( Subtotal = $21,399,061 ) (Continued on the next page) |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01ES031511 | Systems-wide analysis of oxidative stress-responsive m6A epitranscriptome | 000 | 5 | NIH | 3/21/2025 | $402,308 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA268340 | XBP1 Inhibition and STING activation for the treatment of cancer | 000 | 4 | NIH | 3/14/2025 | $517,036 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01NS121405 | S100A4 mediated immune suppression in GBM | 000 | 5 | NIH | 2/14/2025 | $394,788 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL163535 | Human Atherogenesis with Underlying Dysfunctional HDL-Free Cholesterol | 000 | 3 | NIH | 3/11/2025 | $673,341 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R13NS141592 | 2025 Patrica Levy Zusman International Workshop on Neuroregeneration | 000 | 1 | NIH | 2/28/2025 | $14,000 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R21AI190338 | Mechanisms of Resistance and Clinical Outcomes of non-Carbapenemase Producing Carbapenem-Resistant Klebsiella pneumoniae Infections | 000 | 1 | NIH | 2/28/2025 | $259,461 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG077685 | Central and peripheral immune cross-talk in Alzheimer's disease and their modulation by a novel immunotherapy | 000 | 3 | NIH | 2/14/2025 | $592,201 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01NS140292 | DeepStroke+: An Advanced Mobile AI Diagnostic Tool for Fast and Precise Detection of Acute Strokes in Mobile Stroke Units, Emergency Rooms, and Telestroke Triage | 000 | 1 | NIH | 1/31/2025 | $619,969 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI146257 | Gut microbiome communication with the bone marrow regulates intestinal inflammation. | 002 | 6 | NIH | 3/28/2025 | $403,750 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA285209 | Tumor-specific CD8+ Tc9 cells activate host CD4+ T cells to control antigen-lost tumors | 000 | 2 | NIH | 11/19/2024 | $440,870 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R61CA278458 | A multiplexed high-throughput platform to report pharmacologic alteration of cancer stem cell membrane potential and cell cycle state | 001 | 2 | NIH | 5/23/2025 | $22,333 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R61CA278458 | A multiplexed high-throughput platform to report pharmacologic alteration of cancer stem cell membrane potential and cell cycle state | 000 | 2 | NIH | 4/7/2025 | $200,994 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | K23AI185174 | Pathogen and patient determinants of Candida gut colonization in critically ill patients | 000 | 2 | NIH | 5/16/2025 | $194,036 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | T32AI179595 | Antimicrobial Resistance Training Program in the Texas Medical Center (AMR-TPT) | 000 | 2 | NIH | 4/18/2025 | $341,711 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI106200 | Control of dysfunctional Tregs | 000 | 10 | NIH | 1/15/2025 | $469,966 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288884 | Functional roles of mTOR in tumor persistence | 000 | 2 | NIH | 4/17/2025 | $360,978 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288884 | Functional roles of mTOR in tumor persistence | 001 | 2 | NIH | 5/22/2025 | $40,109 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA269835 | Mechanisms of STING in malignant progression and therapy of CLL. | 000 | 3 | NIH | 1/24/2025 | $442,928 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01DK132104 | Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetes | 000 | 4 | NIH | 4/28/2025 | $697,245 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG071496 | Systematic modeling and prediction of cell-type-specific and spatiotemporal crosstalk pathways in Alzheimer's Disease | 000 | 5 | NIH | 4/1/2025 | $711,722 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA253865 | Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer | 001 | 5 | NIH | 5/22/2025 | $39,803 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA253865 | Nanoparticle delivery of miRNA-based therapeutics to overcome clinical challenges in triple negative breast cancer | 000 | 5 | NIH | 3/5/2025 | $358,221 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI176558 | Regulation of Cell Death in HIV Reservoirs | 000 | 3 | NIH | 2/28/2025 | $575,980 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL174587 | Advancing Endovascular PAD Treatment: Overcoming Critical Knowledge Gaps with MRI-histology | 000 | 2 | NIH | 5/7/2025 | $719,088 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI167659 | Long-acting multi prevention implant for 2-year contraception and HIV PrEP | 000 | 3 | NIH | 3/28/2025 | $817,162 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI146048 | Molecular mechanism of streptococcal adaptation to host nutritional defenses | 000 | 6 | NIH | 1/17/2025 | $173,799 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL168277 | Cardiac Autonomic Activation In Atrial Fibrillation Triggers And Substrate | 001 | 3 | NIH | 2/28/2025 | $722,692 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01EY026156 | The Impact of Sleep on Network Coding and Perceptual Performance | 000 | 9 | NIH | 1/8/2025 | $475,319 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA163910 | Targeting ER stress response in B-cell chronic lymphocytic leukemia | 000 | 12 | NIH | 1/22/2025 | $403,750 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA280746 | Targeting phenethyl isothiocyanate to mitochondria in lung carcinogenesis | 000 | 2 | NIH | 1/8/2025 | $562,925 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL158703 | Mechanisms driving cardiac dysfunction in Autosomal Dominant Polycystic Kidney Disease | 000 | 4 | NIH | 4/10/2025 | $403,750 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288403 | Decoupling acute toxicities and antitumor efficacy in adoptive cell therapy | 001 | 2 | NIH | 5/26/2025 | $59,380 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288403 | Decoupling acute toxicities and antitumor efficacy in adoptive cell therapy | 000 | 2 | NIH | 4/18/2025 | $534,430 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA175397 | Distinct Tumor and Metastatic Collagen Microenvironments: Divergent Targeting Approaches | 004 | 11 | NIH | 5/22/2025 | $385,560 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA288613 | Advancing Thyroid Cancer Diagnostics with AI-enhanced Multimodal Optical Histopathology | 000 | 1 | NIH | 12/25/2024 | $593,383 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG080925 | Proteomics based mapping of cardiac extracellular matrix to define sex and age-dependent changes. | 005 | 4 | NIH | 5/7/2025 | -$168,099 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG080925 | Proteomics based mapping of cardiac extracellular matrix to define sex and age-dependent changes. | 004 | 4 | NIH | 5/7/2025 | $168,099 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AG080925 | Proteomics based mapping of cardiac extracellular matrix to define sex and age-dependent changes. | 002 | 4 | NIH | 3/27/2025 | $566,366 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL177797 | Role of Cdk9 in the Pathogenesis of Pulmonary Fibrosis | 001 | 1 | NIH | 2/25/2025 | $0 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01HL177797 | Role of Cdk9 in the Pathogenesis of Pulmonary Fibrosis | 000 | 1 | NIH | 12/31/2024 | $705,334 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01DK134340 | A randomized, sham-controlled clinical trial evaluating individualized neuromodulation of cortical regions involved in neurogenic overactive bladder in Multiple Sclerosis | 000 | 3 | NIH | 12/18/2024 | $305,092 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R21AI182870 | Novel translational strategies to combat group B streptococcus infections | 000 | 1 | NIH | 11/12/2024 | $242,250 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01AI179616 | Modulation of chromatin dynamics to promote transplant survival | 000 | 2 | NIH | 11/5/2024 | $609,980 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA278911 | Induction of autosis to overcome resistance in adoptive cell therapy for solid tumors | 001 | 3 | NIH | 5/22/2025 | $56,868 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA278911 | Induction of autosis to overcome resistance in adoptive cell therapy for solid tumors | 000 | 3 | NIH | 3/13/2025 | $511,814 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01MH127979 | Targeting the HIV-1 Reservoir in Myeloid Cells | 000 | 5 | NIH | 5/2/2025 | $411,093 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA258477 | The Unique Roles of Tumor-Specific Th9 Cells for Solid Tumor Eradication | 001 | 5 | NIH | 5/22/2025 | $39,674 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA258477 | The Unique Roles of Tumor-Specific Th9 Cells for Solid Tumor Eradication | 000 | 5 | NIH | 2/14/2025 | $357,063 |
| | 2025 | 2025 | METHODIST HOSPITAL, THE | 6670 BERTNER AVE | HOUSTON | TX | 77030-2602 | HARRIS | USA | R01CA268340 | XBP1 Inhibition and STING activation for the treatment of cancer | 001 | 4 | NIH | 5/23/2025 | $57,448 |
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