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 | Issue Date FY: 2023 ( Subtotal = $15,847,070 ) (Continued on the next page) |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R25HG006682 | Promoting Diversity, Equity, Inclusion, and Belonging in Genomic Research. | 001 | 11 | NIH | 1/25/2023 | $291,588 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 002 | 3 | NIH | 3/13/2023 | -$300,000 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 001 | 3 | NIH | 2/9/2023 | $300,000 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R00AG065516 | Ultralong-term single-molecule imaging of amyloid precursor protein (APP) processing in Alzheimer's disease | 000 | 3 | NIH | 11/30/2022 | $248,363 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R01MH129722 | 2/4 The Autism Sequencing Consortium: Discovering autism risk genes and how they impact core features of the disorder | 000 | 2 | NIH | 1/6/2023 | $345,363 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 001 | 3 | NIH | 2/9/2023 | $300,000 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 001 | 3 | NIH | 2/9/2023 | $300,000 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R01CA276865 | Spatial genomic tools to interrogate T cell clonotypes, tumor clones and the microenvironment | 000 | 1 | NIH | 1/30/2023 | $691,271 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | K99NS125131 | Determining the Role of Distinct Parafascicular Thalamic Circuits in Motor Behaviors Relevant to Parkinson?s Disease | 000 | 2 | NIH | 11/30/2022 | $108,316 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 001 | 3 | NIH | 2/9/2023 | $338,468 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | K99CA277583 | AI-Powered Uncovering of Mechanisms in Cancer Through Causal Discovery Analysis and Generative Modeling of Heterogeneous Data | 000 | 1 | NIH | 1/27/2023 | $138,349 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | K00DK123834 | NBCe1-mediated Regulation of HCO3- is a Novel Mechanism Underlying Metabolic Reprogramming and Cystogenesis | 000 | 4 | NIH | 2/24/2023 | $89,786 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R00AG065516 | Ultralong-term single-molecule imaging of amyloid precursor protein (APP) processing in Alzheimer's disease | 001 | 3 | NIH | 12/14/2022 | -$248,363 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U01MH124602 | A cellular atlas of the primate and human basal ganglia | 001 | 3 | NIH | 11/8/2022 | $0 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U01MH124602 | A cellular atlas of the primate and human basal ganglia | 002 | 3 | NIH | 2/6/2023 | $170,661 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R35GM122547 | Advancing image-based profiling | 001 | 6 | NIH | 2/3/2023 | $636,740 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | K00CA264422 | A visible machine learning system to discover targeted treatment solutions in cancer | 000 | 3 | NIH | 3/9/2023 | $92,988 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U01MH124602 | A cellular atlas of the primate and human basal ganglia | 000 | 3 | NIH | 11/4/2022 | $1,535,947 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R21CA269103 | Stitch-seq for genome-wide pooled genomic screening with RNA-seq readout | 000 | 2 | NIH | 2/20/2023 | $167,252 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R01NS125255 | How Substrate Dosage Drives Prion Disease Kinetics | 000 | 2 | NIH | 11/23/2022 | $504,481 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | UH3MH120096 | Development and validation of AAV vectors to manipulate specific neuronal subtypes and circuits involved in epilepsy and psychiatric disorders across mammalian species. | 000 | 4 | NIH | 2/10/2023 | $2,428,662 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | K25AI168451 | Physical Biology and Deep Learning for Antibiotic Resistance and Discovery | 002 | 2 | NIH | 2/15/2023 | $109,232 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | OT2TR003437 | A Translator Knowledge Provider for Systems Chemical Biology | 001 | 1 | NIH | 12/21/2022 | $711,299 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | OT2TR003437 | A Translator Knowledge Provider for Systems Chemical Biology | 002 | 1 | NIH | 2/17/2023 | $0 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | P41GM135019 | Center for Open Bioimage Analysis | 001 | 4 | NIH | 3/2/2023 | $126,283 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R00AG065516 | Ultralong-term single-molecule imaging of amyloid precursor protein (APP) processing in Alzheimer's disease | 001 | 3 | NIH | 12/14/2022 | $248,363 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | OT2TR003433 | A Complex Disease Genetics Knowledge Provider for Biomedical Data Translator | 001 | 1 | NIH | 12/7/2022 | $484,013 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | P41GM135019 | Center for Open Bioimage Analysis | 000 | 4 | NIH | 12/2/2022 | $1,136,551 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R01NS125255 | How Substrate Dosage Drives Prion Disease Kinetics | 001 | 2 | NIH | 1/30/2023 | $56,053 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R21MH129560 | Identifying cortical circuit changes in Akap11 mutant mice | 000 | 2 | NIH | 3/3/2023 | $195,000 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R01EB031172 | Continuous Evolution of Proteins with Novel Therapeutic Potential | 000 | 3 | NIH | 1/26/2023 | $621,853 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R01GM137606 | Chemical approaches for precision genome editing | 000 | 3 | NIH | 2/10/2023 | $362,632 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R33NS119717 | Development of Prion Protein-Lowering Divalent siRNA Therapy for Prion Disease | 000 | 3 | NIH | 11/21/2022 | $348,908 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011450 | The Genome Aggregation Database (gnomAD) | 001 | 3 | NIH | 2/16/2023 | $244,400 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011450 | The Genome Aggregation Database (gnomAD) | 000 | 3 | NIH | 1/23/2023 | $2,199,600 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R33NS119717 | Development of Prion Protein-Lowering Divalent siRNA Therapy for Prion Disease | 001 | 3 | NIH | 1/30/2023 | $38,767 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 002 | 3 | NIH | 3/13/2023 | $300,000 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 002 | 3 | NIH | 3/13/2023 | $100,000 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R01HL157717 | Cardiovascular disease, metabolic syndrome, microbes and metabolites in FHS | 000 | 2 | NIH | 3/15/2023 | $955,901 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R01MH129722 | 2/4 The Autism Sequencing Consortium: Discovering autism risk genes and how they impact core features of the disorder | 001 | 2 | NIH | 2/23/2023 | $38,374 |
| | 2023 | 2023 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R25HG006682 | Promoting Diversity, Equity, Inclusion, and Belonging in Genomic Research. | 002 | 11 | NIH | 3/1/2023 | $32,399 |
| | 2023 | 2022 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG010262 | The AnVIL Data Ecosystem | 000 | 5 | NIH | 10/14/2022 | $0 |
| | 2023 | 2022 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | DP5OD033430 | Transposable Element Interaction and Its Impact on Human Development and Health | 000 | 1 | NIH | 10/17/2022 | $0 |
| | 2023 | 2022 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | OT2DB000010 | RADx Data Hub | 000 | 1 | NIH | 12/12/2022 | $0 |
| | 2023 | 2022 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | OT2DB000010 | RADx Data Hub | 001 | 1 | NIH | 1/10/2023 | $0 |
| | 2023 | 2022 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 000 | 2 | NIH | 11/25/2022 | $0 |
| | 2023 | 2022 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | R21AR080274 | Cultured human fetal dermal extracellular matrix for scarless wound healing | 000 | 1 | NIH | 11/10/2022 | $0 |
| | 2023 | 2022 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | K99HL163805 | In vivo precision genome editing to correct genetic disease | 000 | 1 | NIH | 3/4/2023 | $0 |
| | 2023 | 2022 | BROAD INSTITUTE, INC., THE | 415 MAIN ST | CAMBRIDGE | MA | 02142-1027 | MIDDLESEX | USA | U24HG011025 | The Global Alliance for Genomics and Health: Setting the Standards for Genomics and Health-Related Data Sharing | 000 | 2 | NIH | 11/25/2022 | $0 |
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