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 | Issue Date FY: 2026 ( Subtotal = $5,413,216 ) (Continued on the next page) |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI040459 | Post-Transplant Inflammatory Response | 000 | 27 | NIH | 12/9/2025 | $521,522 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK137822 | Actin methylation as a novel mechanism that regulates gut barrier integrity and repair | 000 | 3 | NIH | 1/6/2026 | $532,335 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA277966 | Macrophage-based Therapy and Immune Checkpoint Blockade for Glioblastoma | 000 | 4 | NIH | 12/10/2025 | $331,459 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01MH133584 | Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors | 000 | 2 | NIH | 12/1/2025 | $402,500 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA244613 | Exploiting Ecology and Evolution to Prevent Therapy Resistance in EGFR-Driven Lung Cancer | 000 | 7 | NIH | 12/23/2025 | $447,758 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI168411 | Innate immune responses to tissue infection by intestinal fungi inhibit wound repair | 000 | 3 | NIH | 11/26/2025 | $795,346 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DE033391 | Molecular mechanism of Zika virus-induced premature craniofacial suture closure | 000 | 3 | NIH | 1/13/2026 | $60,375 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG080486 | Digital Twin Neighborhoods for Research on Geographic Patterns in Mid-Life Health Trajectories | 000 | 4 | NIH | 12/8/2025 | $572,788 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA295609 | Molecular mediators of disparate outcomes experienced by patients of African ancestry with lung cancer | 000 | 2 | NIH | 1/20/2026 | $331,459 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01EY034755 | Inflammatory Signaling and Regeneration in Zebrafish models of Retinal Degeneration | 000 | 4 | NIH | 1/20/2026 | $515,193 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F32DK136180 | Internalization of dead cells governs intestinal stem cell activity | 000 | 3 | NIH | 12/5/2025 | $81,040 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM156762 | Synthetic biology tools and strategies to streamline the sensing and responding to disease cues in engineered theragnostic bacteria. | 000 | 2 | NIH | 12/22/2025 | $362,250 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R21AI182702 | Modulation of Monocyte and T Cell Functions by Immune Inhibitory Receptors during Subclinical Malaria | 000 | 2 | NIH | 12/29/2025 | $92,588 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R21AI182702 | Modulation of Monocyte and T Cell Functions by Immune Inhibitory Receptors during Subclinical Malaria | 001 | 2 | NIH | 1/7/2026 | $53,795 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F31AI174784 | Host and microbe-dependent mechanisms of enhanced autoimmune susceptibility driven by checkpoint inhibitors | 000 | 3 | NIH | 11/28/2025 | $54,538 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F32CA287655 | A Hyper-Thrombotic State and Immunosuppression in GBM | 000 | 2 | NIH | 12/10/2025 | $78,220 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG097492 | Endothelial TLR2/4 signaling in sex dimorphism of pathological angiogenesis and aging | 000 | 1 | NIH | 12/12/2025 | $659,309 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | U01NS123658 | Optimization of CaMPARI for large-scale, cellular-resolution activity recording in freely-moving mice | 000 | 4 | NIH | 12/19/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | U01NS123658 | Optimization of CaMPARI for large-scale, cellular-resolution activity recording in freely-moving mice | 000 | 4 | NIH | 12/19/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | U01AG073323 | Alzheimer's MultiOme Data Repurposing: Artificial Intelligence, Network Medicine, and Therapeutics Discovery | 000 | 5 | NIH | 11/25/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG070736 | CYCLE-AD: Randomized Controlled Trial to Assess the Efficacy of Indoor Cycling in Slowing Disease Progression in Healthy Older Persons at Genetic Risk for Alzheimers Disease | 000 | 5 | NIH | 10/13/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | UM1HL088955 | Cardiothoracic Surgical Trials Network | 000 | 17 | NIH | 12/4/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG070736 | CYCLE-AD: Randomized Controlled Trial to Assess the Efficacy of Indoor Cycling in Slowing Disease Progression in Healthy Older Persons at Genetic Risk for Alzheimers Disease | 000 | 5 | NIH | 10/13/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08AA028794 | Mechanisms of HIF1 alpha mediated dysregulated skeletal muscle proteostasis in alcoholic liver disease | 000 | 5 | NIH | 12/4/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL155064 | TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung Injury | 000 | 5 | NIH | 11/4/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI153348 | HCMV GPCR functions during latency and reactivation | 000 | 5 | NIH | 1/20/2026 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS119178 | The role of the astrocyte immunoproteasome during chronic CNS autoimmunity | 000 | 5 | NIH | 10/7/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AT011905 | Sensing active movement of the self: reconsidering the cellular basis kinesthesia | 000 | 4 | NIH | 11/4/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI160740 | Mechanisms of alloantibody production following renal transplantation | 000 | 5 | NIH | 11/4/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA257502 | Discovering the role of YES1 in triple negative breast cancer | 000 | 5 | NIH | 1/20/2026 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK126772 | Unraveling strain-level variation in the induction of anti-inflammatory responses in the intestine | 000 | 5 | NIH | 10/8/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI150931 | Manipulation of host factors that promote HCMV latency | 000 | 5 | NIH | 1/20/2026 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG092298 | Neural Mechanisms underlying the benefits of Aerobic Exercise in Advanced Parkinson's disease | 000 | 1 | NIH | 12/4/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HD105049 | Modeling Autism and Comorbid Cancer Risk in Individuals with Germline PTEN Mutations | 000 | 4 | NIH | 12/11/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R21CA293274 | Evaluating the adoption, implementation, and maintenance of a cervical precancer treatment in El Salvador | 000 | 1 | NIH | 12/3/2025 | $0 |
| | 2026 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23HL150279 | Novel Cardiac MRI-Based Predictors for Tetralogy of Fallot: Deformation, Kinematic, and Geometric Analyses | 000 | 5 | NIH | 12/18/2025 | $0 |
| | 2026 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08DE029503 | Remodeling host immunity in oral cancer with personalized RNA nanoparticle vaccines | 000 | 6 | NIH | 1/6/2026 | -$2,206 |
| | 2026 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00AG066862 | ASC oligomerization and transmission as an initiating event for protein aggregation in Synucleinopathy Dementias | 000 | 5 | NIH | 1/21/2026 | $0 |
| | 2026 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | U01NS100610 | Dementia with Lewy Bodies Consortium | 000 | 8 | NIH | 1/2/2026 | $0 |
| | 2026 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R56AR083376 | Effect of RCR healing on degenerative shoulder changes and 5y clinical outcomes | 000 | 1 | NIH | 11/19/2025 | $0 |
| | 2026 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AA028190 | Novel mechanism based treatment to improve tissue injury in alcoholic hepatitis | 000 | 5 | NIH | 1/14/2026 | $0 |
| | 2026 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35CA232097 | Towards Precision Immuno-Oncology: Unraveling the Genomic Determinants and Mechanisms Underlying Immunotherapy Efficacy and Resistance | 000 | 8 | NIH | 12/18/2025 | -$1 |
| | 2026 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K01AA029474 | The role of PDK4 in alcohol-associated liver disease | 000 | 4 | NIH | 11/20/2025 | $0 |
| | 2026 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00CA240689 | Determining the Immunological Consequences of DNA Replication Stress Response Defects in Renal Cells Carcinoma to Improve Immunotherapy Outcomes | 000 | 5 | NIH | 12/11/2025 | -$39,606 |
| | 2026 | 2023 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK130377 | The Untranslated 3'End of SARS-CoV-2 RNA as a Determinant of Obesity-Accelerated Infectivity | 000 | 3 | NIH | 12/15/2025 | $0 |
| | 2026 | 2023 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA218195 | Comparison of cervical intraepithelial neoplasia 2/3 treatment outcomes with a portable LMIC-adapted thermal ablation device vs. gas-based cryotherapy | 000 | 6 | NIH | 11/20/2025 | -$13,129 |
| | 2026 | 2023 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | P01HL147823 | Gut Microbiota and Cardiometabolic Diseases | 000 | 5 | NIH | 1/19/2026 | -$14,527 |
| | 2026 | 2023 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00DE028973 | Deamidation-mediated metabolic reprogramming by KSHV in cell proliferation and tumorigenesis | 000 | 5 | NIH | 12/3/2025 | -$7,412 |
| | 2026 | 2022 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AA026764 | Specific-sized hyaluronan: a dual targeted therapy for ALD | 000 | 5 | NIH | 12/5/2025 | $0 |
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