| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2026 ( Subtotal = $21,968,932 ) (Continued on the next page) |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL167113 | A SkeleTal muscle Recovery Intervention with Dietary protein in Heart Failure (ASTRID-HF) | 000 | 4 | NIH | 1/30/2026 | $307,426 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM156762 | Synthetic biology tools and strategies to streamline the sensing and responding to disease cues in engineered theragnostic bacteria. | 001 | 2 | NIH | 3/11/2026 | $40,250 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL162772 | Novel regulation of beta-adrenergic receptor function by phosphoinositide 3-kinase | 000 | 4 | NIH | 3/19/2026 | $605,844 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL169427 | Developing hemophilia A therapeutics by targeting translational and posttranslational regulation of FVIII | 000 | 3 | NIH | 3/19/2026 | $492,171 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI195504 | Regulation of donor specific antibody production | 000 | 1 | NIH | 3/30/2026 | $690,359 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS123532 | Understanding role of circadian disruption in pathogenesis of MS | 000 | 5 | NIH | 3/31/2026 | $446,361 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK135265 | Mechanisms of Kidney Diseases Associated With APOL1 Variation | 000 | 4 | NIH | 3/31/2026 | $678,596 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL166544 | The vital role of T403 phosphorylation of STAT2 in post-viral bacterial pneumonia | 001 | 3 | NIH | 3/13/2026 | $16,905 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA300540 | Assessing feasibility of gastric cancer screening in the US | 000 | 2 | NIH | 4/1/2026 | $539,073 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F32DK136180 | Internalization of dead cells governs intestinal stem cell activity | 001 | 3 | NIH | 3/26/2026 | $1,308 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM162199 | Gasdermin-D tags mitochondria to serve as mobile propagators of inflammatory responses | 000 | 1 | NIH | 3/24/2026 | $431,750 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R33HL171717 | Small Molecule Therapeutic for Heart Failure | 000 | 3 | NIH | 3/31/2026 | $471,000 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL179780 | Gut Microbe-Derived Lipids Shape Chronic Inflammation in Cardiometabolic Disease | 001 | 2 | NIH | 3/27/2026 | $22,298 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA244613 | Exploiting Ecology and Evolution to Prevent Therapy Resistance in EGFR-Driven Lung Cancer | 000 | 7 | NIH | 12/23/2025 | $447,758 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HG010092 | Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes | 000 | 8 | NIH | 3/6/2026 | $769,693 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124581 | Childhood-onset hypomyelinating leukodystrophy and the multi-tRNA synthetase complex | 000 | 4 | NIH | 2/26/2026 | $626,635 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R33CA286797 | Microbiome-Mediated Tumor Immunomodulation in a Pathomimetic Colorectal Cancer Chip | 000 | 2 | NIH | 2/27/2026 | $400,890 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM149240 | Immune Function in Sepsis: Role of Sirtuin | 000 | 4 | NIH | 2/27/2026 | $402,500 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K01NS136791 | Analysis of C9ORF72-associated poly (GR) interactions on BAF chromatin remodeling complex structure and function | 000 | 2 | NIH | 2/26/2026 | $236,668 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG092591 | A Multimodal, Multiscale and Multistage Systems Biology (M3SB) Infrastructure for Precision Medicine in Alzheimer’s Disease and Longevity | 000 | 2 | NIH | 2/25/2026 | $786,784 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124081 | lncRNA regulation of glioblastoma progression and therapeutic resistance | 001 | 5 | NIH | 2/28/2026 | $54,720 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124547 | The mammalian multi-tRNA synthetase complex | 001 | 5 | NIH | 2/28/2026 | $48,189 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R21AI182702 | Modulation of Monocyte and T Cell Functions by Immune Inhibitory Receptors during Subclinical Malaria | 001 | 2 | NIH | 1/7/2026 | $53,795 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL166544 | The vital role of T403 phosphorylation of STAT2 in post-viral bacterial pneumonia | 000 | 3 | NIH | 2/24/2026 | $535,325 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS132437 | The Interplay between Genetics and Aerobic Exercise to Slow Parkinson's disease (GEARS) Trial | 001 | 3 | NIH | 2/28/2026 | $61,387 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R21AI182702 | Modulation of Monocyte and T Cell Functions by Immune Inhibitory Receptors during Subclinical Malaria | 000 | 2 | NIH | 12/29/2025 | $92,588 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DE033391 | Molecular mechanism of Zika virus-induced premature craniofacial suture closure | 000 | 3 | NIH | 1/13/2026 | $60,375 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM156762 | Synthetic biology tools and strategies to streamline the sensing and responding to disease cues in engineered theragnostic bacteria. | 000 | 2 | NIH | 12/22/2025 | $362,250 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA295609 | Molecular mediators of disparate outcomes experienced by patients of African ancestry with lung cancer | 000 | 2 | NIH | 1/20/2026 | $331,459 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01EY034755 | Inflammatory Signaling and Regeneration in Zebrafish models of Retinal Degeneration | 000 | 4 | NIH | 1/20/2026 | $515,193 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK137822 | Actin methylation as a novel mechanism that regulates gut barrier integrity and repair | 000 | 3 | NIH | 1/6/2026 | $532,335 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HD114650 | The I-SCORE (Intensive Stroke Cycling for Optimal Recovery and Economic value) Trial | 000 | 3 | NIH | 3/2/2026 | $626,754 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI167939 | Chronic Antibody-Mediated Rejection of Kidney Allografts | 000 | 5 | NIH | 1/28/2026 | $646,362 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01MH133584 | Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors | 000 | 2 | NIH | 12/1/2025 | $402,500 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG086247 | Improving colorectal cancer screening decisions through consideration of life expectancy | 001 | 2 | NIH | 3/2/2026 | $69,499 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG080486 | Digital Twin Neighborhoods for Research on Geographic Patterns in Mid-Life Health Trajectories | 001 | 4 | NIH | 3/2/2026 | $63,643 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI168411 | Innate immune responses to tissue infection by intestinal fungi inhibit wound repair | 000 | 3 | NIH | 11/26/2025 | $795,346 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F31AI174784 | Host and microbe-dependent mechanisms of enhanced autoimmune susceptibility driven by checkpoint inhibitors | 000 | 3 | NIH | 11/28/2025 | $54,538 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI040459 | Post-Transplant Inflammatory Response | 000 | 27 | NIH | 12/9/2025 | $521,522 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL179780 | Gut Microbe-Derived Lipids Shape Chronic Inflammation in Cardiometabolic Disease | 000 | 2 | NIH | 3/4/2026 | $706,137 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS137230 | Molecular Mechanism of Glucocorticoid Receptor, Cytochrome P450, and P-Glycoprotein Axis on Drug Regulation at the Blood-Brain Barrier in Epilepsy with Focal Cortical Dysplasia | 000 | 2 | NIH | 2/26/2026 | $431,676 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL172805 | Artificial sweeteners and cardiovascular disease | 000 | 2 | NIH | 2/16/2026 | $756,574 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01GM147138 | Interplay between LINE-1 retrotransposons, condensins, and IFN | 000 | 4 | NIH | 2/12/2026 | $403,843 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG080486 | Digital Twin Neighborhoods for Research on Geographic Patterns in Mid-Life Health Trajectories | 000 | 4 | NIH | 12/8/2025 | $572,788 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK114425 | Imaging Assessments of ARPKD Kidney Disease Progression | 000 | 6 | NIH | 2/12/2026 | $682,790 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG097492 | Endothelial TLR2/4 signaling in sex dimorphism of pathological angiogenesis and aging | 000 | 1 | NIH | 12/12/2025 | $659,309 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS146421 | Pathogenesis of Permanent Neurological Disability in Multiple Sclerosis | 000 | 1 | NIH | 2/10/2026 | $544,568 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R13AR083805 | Clinical Scholars Career Development Program (CSCDP) | 000 | 3 | NIH | 2/9/2026 | $30,000 |
| | 2026 | 2026 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F32DK136180 | Internalization of dead cells governs intestinal stem cell activity | 000 | 3 | NIH | 12/5/2025 | $81,040 |
|
