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 | Issue Date FY: 2025 ( Subtotal = $39,521,360 ) (Continued on the next page) |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AT011905 | Sensing active movement of the self: reconsidering the cellular basis kinesthesia | 000 | 4 | NIH | 1/16/2025 | $499,836 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL167113 | A SkeleTal muscle Recovery Intervention with Dietary protein in Heart Failure (ASTRID-HF) | 000 | 3 | NIH | 1/28/2025 | $273,754 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DE033632 | CDK6-dependent metabolic reprogramming in KSHV pathogenesis | 000 | 2 | NIH | 5/15/2025 | $404,468 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM149240 | Immune Function in Sepsis: Role of Sirtuin | 001 | 3 | NIH | 2/20/2025 | $362,250 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK131550 | Novel cytoskeletal mechanisms of pathogenic bacteria interactions with intestinal epithelium | 000 | 4 | NIH | 4/16/2025 | $506,825 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08HL159236 | Developing a Donor-Candidate Risk Prediction System to Optimize Lung Allocation and Transplant Outcomes | 000 | 4 | NIH | 4/1/2025 | $151,077 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL155064 | TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung Injury | 000 | 5 | NIH | 2/26/2025 | $382,925 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HG010092 | Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes | 001 | 7 | NIH | 5/2/2025 | $76,078 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HG010092 | Engaging Patients in Prenatal Genetic Testing Decisions as a Pathway to Improve Obstetric Outcomes | 000 | 7 | NIH | 3/4/2025 | $684,709 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01GM147138 | Interplay between LINE-1 retrotransposons, condensins, and IFN | 000 | 3 | NIH | 2/20/2025 | $361,100 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F32HD114499 | The role of retrotransposonable elements in neurodevelopment and disease | 000 | 2 | NIH | 3/11/2025 | $76,756 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F31CA290723 | SMARCA5 Inhibition as a Therapeutic Target for Glioblastoma | 000 | 1 | NIH | 5/1/2025 | $41,312 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL179780 | Gut Microbe-Derived Lipids Shape Chronic Inflammation in Cardiometabolic Disease | 000 | 1 | NIH | 4/25/2025 | $743,302 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL173543 | Mitochondria in cardiomyocyte-fibroblast transcellular cross-talk | 000 | 1 | NIH | 5/12/2025 | $639,621 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI150931 | Manipulation of host factors that promote HCMV latency | 000 | 5 | NIH | 4/1/2025 | $477,589 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI153173 | Uncovering aryl polyene biology to identify new drug targets in Gram-negative bacterial pathogens | 000 | 5 | NIH | 4/7/2025 | $402,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08AA028794 | Mechanisms of HIF1 alpha mediated dysregulated skeletal muscle proteostasis in alcoholic liver disease | 000 | 5 | NIH | 4/24/2025 | $179,129 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08DK137042 | Deep Learning of Renal Scans and Kidney Ultrasounds in Children with Antenatal Hydronephrosis | 000 | 1 | NIH | 3/4/2025 | $155,011 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00EY033909 | The role of neuronal activity on retinal angiogenesis and blood-retina barrier (BRB) maturation | 000 | 3 | NIH | 4/23/2025 | $248,999 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL172805 | Artificial sweeteners and cardiovascular disease | 000 | 1 | NIH | 3/4/2025 | $796,395 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01GM121428 | The effect of nucleosomes on the earliest stages of RNA polymerase II transcription | 002 | 6 | NIH | 5/14/2025 | $373,119 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS136997 | Neural Coding and Control of Pain Detection in Somatosensory Cortex | 000 | 1 | NIH | 3/28/2025 | $560,934 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23AT012484 | A Daily, Digital Mindfulness-Based Intervention for Depressive Symptoms After Serious Illness | 000 | 1 | NIH | 3/24/2025 | $165,240 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA300540 | Assessing feasibility of gastric cancer screening in the US | 000 | 1 | NIH | 3/20/2025 | $564,414 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R33CA286797 | Microbiome-Mediated Tumor Immunomodulation in a Pathomimetic Colorectal Cancer Chip | 000 | 1 | NIH | 2/24/2025 | $400,890 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R21CA288795 | Targeting NEK2 to potentiate standard of care therapies for breast cancer | 000 | 2 | NIH | 2/14/2025 | $203,222 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL058758 | Molecular basis of ILK-mediated cell adhesion | 002 | 24 | NIH | 3/20/2025 | $495,369 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R03EB034863 | Development of motion correction algorithms for functional MRI data using a custom simultaneously excited multi-slice MRI acquisition with prospectively injected motion | 000 | 1 | NIH | 1/21/2025 | $80,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01EY034755 | Inflammatory Signaling and Regeneration in Zebrafish models of Retinal Degeneration | 000 | 3 | NIH | 1/24/2025 | $515,193 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08HL168348 | Nocturnal hypoxemia dysregulates skeletal muscle protein homeostasis in COPD | 000 | 1 | NIH | 12/24/2024 | $151,578 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F31EY035133 | Characterizing the role of mitochondrial DNA mutations on retinal degeneration. | 000 | 2 | NIH | 1/14/2025 | $48,974 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23HL150279 | Novel Cardiac MRI-Based Predictors for Tetralogy of Fallot: Deformation, Kinematic, and Geometric Analyses | 000 | 5 | NIH | 1/28/2025 | $159,163 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R21AI182702 | Modulation of Monocyte and T Cell Functions by Immune Inhibitory Receptors during Subclinical Malaria | 000 | 1 | NIH | 12/19/2024 | $184,109 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG086247 | Improving colorectal cancer screening decisions through consideration of life expectancy | 000 | 1 | NIH | 12/31/2024 | $625,452 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM156762 | Synthetic biology tools and strategies to streamline the sensing and responding to disease cues in engineered theragnostic bacteria. | 000 | 1 | NIH | 12/26/2024 | $402,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA295609 | Molecular mediators of disparate outcomes experienced by patients of African ancestry with lung cancer | 000 | 1 | NIH | 12/4/2024 | $368,288 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K01NS136791 | Analysis of C9ORF72-associated poly (GR) interactions on BAF chromatin remodeling complex structure and function | 000 | 1 | NIH | 12/10/2024 | $236,668 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01MH133584 | Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors | 001 | 1 | NIH | 4/21/2025 | $353,125 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01MH133584 | Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors | 000 | 1 | NIH | 12/13/2024 | $241,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DE033391 | Molecular mechanism of Zika virus-induced premature craniofacial suture closure | 001 | 2 | NIH | 5/5/2025 | $40,250 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DE033391 | Molecular mechanism of Zika virus-induced premature craniofacial suture closure | 000 | 2 | NIH | 12/17/2024 | $362,250 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23ES035447 | Air Pollution, Environmental Injustice and Progressive Pulmonary Fibrosis | 000 | 1 | NIH | 12/12/2024 | $241,811 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS137230 | Molecular Mechanism of Glucocorticoid Receptor, Cytochrome P450, and P-Glycoprotein Axis on Drug Regulation at the Blood-Brain Barrier in Epilepsy with Focal Cortical Dysplasia | 000 | 1 | NIH | 12/5/2024 | $431,676 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK132038 | Septins in intestinal fibrosis | 000 | 3 | NIH | 4/25/2025 | $630,078 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124081 | lncRNA regulation of glioblastoma progression and therapeutic resistance | 000 | 4 | NIH | 11/20/2024 | $492,501 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23MD017284 | Improving Black sarcoidosis patients’ care with a collaboratively developed, patient centered program | 002 | 4 | NIH | 5/1/2025 | $159,992 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL167831 | Gut microbial dietary phenylalanine metabolism and heart failure | 000 | 2 | NIH | 1/13/2025 | $711,062 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG082382 | Novel oxidative pathway targets microglia in Alzheimer's disease | 000 | 2 | NIH | 4/21/2025 | $704,702 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI181758 | KSHV-mediated metabolic reprogramming for LANA expression and viral persistency | 000 | 2 | NIH | 5/9/2025 | $675,416 |
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