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 | Issue Date FY: 2025 ( Subtotal = $1,898,109 ) |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI168411 | Innate immune responses to tissue infection by intestinal fungi inhibit wound repair | 000 | 2 | NIH | 11/4/2024 | $771,486 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL160747 | Gut-microbial metabolism of aromatic amino acids and cardiovascular disease | 000 | 4 | NIH | 11/6/2024 | $502,296 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI040459 | Post-Transplant Inflammatory Response | 000 | 26 | NIH | 11/15/2024 | $505,876 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00DE031372 | Role of sulfide in oral microbiota-host interactions that promote periodontitis | 000 | 4 | NIH | 10/25/2024 | $249,000 |
| | 2025 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35HG011922 | Model-based methods for single cell chromatin interactomic data | 000 | 4 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R33AG069729 | A Cognitive Risk Calculator and Screening tool for Primary Care Settings | 000 | 5 | NIH | 11/15/2024 | $0 |
| | 2025 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | P30AG072959 | Cleveland Alzheimers Disease Research Center | 000 | 4 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | U01DK114908 | Cleveland Precision Medicine Chronic Kidney Disease Cohort | 000 | 8 | NIH | 11/14/2024 | $0 |
| | 2025 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM149240 | Immune Function in Sepsis: Role of Sirtuin | 000 | 2 | NIH | 11/7/2024 | $0 |
| | 2025 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01EB024573 | Reproducibility in simulation-based prediction of natural knee mechanics | 000 | 6 | NIH | 10/15/2024 | $0 |
| | 2025 | 2023 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00CA234097 | Targeting ZDHHC13-activated palmitoylation for melanoma treatment | 000 | 5 | NIH | 10/21/2024 | -$14,319 |
| | 2025 | 2022 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23NS109328 | Thalamic MRI, histopathologic, and clinical correlations in multiple sclerosis | 000 | 5 | NIH | 10/22/2024 | -$105,978 |
| | 2025 | 2021 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | OT2OD023873 | Conscious ambulatory bladder monitoring to understand neural control of lower urinary tract function | 000 | 1 | NIH | 10/8/2024 | -$10,251 |
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| Issue Date FY: 2024 ( Subtotal = $119,302,221 ) (Continued on the next page) |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG082118 | Characterize neuronal and glial cell-specific vulnerability to proteinopathies in Alzheimer's disease using multimodal single-nuclei genomic and epigenomic approaches | 001 | 2 | NIH | 5/21/2024 | $796,355 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG084250 | Microglial Activation and Inflammatory Endophenotypes Underlying Sex Differences of Alzheimer’s Disease | 001 | 2 | NIH | 5/13/2024 | $560,929 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA238087 | Biological determinants of colorectal cancer outcomes in Latinos of diverseýancestral origins | 000 | 6 | NIH | 5/20/2024 | $120,730 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK126772 | Unraveling strain-level variation in the induction of anti-inflammatory responses in the intestine | 001 | 4 | NIH | 5/14/2024 | $28,874 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K25AR078928 | Automated Arthroscopic Partial Meniscectomy Patient Outcome Prediction using Deep Learning | 000 | 3 | NIH | 6/3/2024 | $135,890 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | T32DK083251 | Combined Training Program in Digestive Disease Sciences | 000 | 14 | NIH | 3/25/2024 | $109,059 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG080486 | Digital Twin Neighborhoods for Research on Place-Based Health Inequalities in Mid-Life | 001 | 2 | NIH | 5/17/2024 | $61,550 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS130798 | Sema3C Signaling as an Alternative Activator of Canonical Wnt Signaling in Glioblastoma | 000 | 2 | NIH | 4/9/2024 | $390,425 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL169290 | Nutrition, terminal NAD metabolites and cardiovascular disease | 001 | 1 | NIH | 5/31/2024 | $78,433 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI167939 | Chronic Antibody-Mediated Rejection of Kidney Allografts | 001 | 3 | NIH | 6/7/2024 | $64,636 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA248048 | A novel determinant of prostate cancer growth | 001 | 4 | NIH | 4/16/2024 | $16,137 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG076448 | TREM2 Genotype-Informed Drug Repurposing and Combination Therapy Design for Alzheimers Disease | 000 | 3 | NIH | 4/15/2024 | $809,747 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F32HD114499 | The role of retrotransposonable elements in neurodevelopment and disease | 002 | 1 | NIH | 6/4/2024 | $4,784 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AA027766 | The role of hippocampal neurogenesis in alcohol withdrawal seizure and cognition | 001 | 5 | NIH | 5/27/2024 | $49,420 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK120830 | Per-Oral Pyloromyotomy (POP) in the treatment of medical refractory gastroparesis : A randomized, sham-controlled trial | 000 | 5 | NIH | 3/26/2024 | $253,575 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS086299 | Regulation of B cells in the CNS | 001 | 10 | NIH | 4/25/2024 | $26,485 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS127374 | Hydrogen sulfide functions as a tumor suppressor in glioblastoma | 001 | 2 | NIH | 4/25/2024 | $36,060 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124581 | Childhood-onset hypomyelinating leukodystrophy and the multi-tRNA synthetase complex | 001 | 2 | NIH | 4/25/2024 | $43,863 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124081 | lncRNA regulation of glioblastoma progression and therapeutic resistance | 001 | 3 | NIH | 4/25/2024 | $38,304 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS119178 | The role of the astrocyte immunoproteasome during chronic CNS autoimmunity | 001 | 4 | NIH | 4/25/2024 | $28,175 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35NS097303 | Pathogenesis of Neurological Disability in Primary Diseases of Myelin | 001 | 8 | NIH | 4/24/2024 | $61,023 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00DE028573 | Molecular regulatory mechanism of Zika virus-induced intracranial calcifications | 000 | 6 | NIH | 4/12/2024 | $248,999 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HD098073 | Contralaterally Controlled FES Combined with Brain Stimulation for Severe Upper limb Hemiplegia | 000 | 5 | NIH | 5/7/2024 | $509,713 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AA027766 | The role of hippocampal neurogenesis in alcohol withdrawal seizure and cognition | 000 | 5 | NIH | 3/27/2024 | $444,782 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK131550 | Novel cytoskeletal mechanisms of pathogenic bacteria interactions with intestinal epithelium | 000 | 3 | NIH | 5/7/2024 | $486,552 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AA031028 | Activity and connectivity of hippocampal newborn neurons underlie alcohol withdrawal-associated syndromes | 000 | 2 | NIH | 5/30/2024 | $632,575 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA251275 | Structural analysis and therapeutic nanobody development of KSHV G-protein coupled receptor | 000 | 5 | NIH | 5/30/2024 | $490,912 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F32DK136180 | Internalization of dead cells governs intestinal stem cell activity | 002 | 1 | NIH | 5/6/2024 | $5,248 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | TL1DK132770 | KUH-TN Training Core | 000 | 4 | NIH | 5/31/2024 | $338,855 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL169290 | Nutrition, terminal NAD metabolites and cardiovascular disease | 000 | 1 | NIH | 4/8/2024 | $705,896 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS117510 | Molecular Genetic Dissection of Fenestrated Vascular Development in the Choroid Plexus | 000 | 5 | NIH | 5/30/2024 | $367,000 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS086299 | Regulation of B cells in the CNS | 000 | 10 | NIH | 3/5/2024 | $340,515 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL155064 | TRPV4 Regulates Mechanosensitive Macrophage Functions in Lung Injury | 000 | 4 | NIH | 1/30/2024 | $382,925 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F31CA284668 | Ribonucleotide Reductase as a Driver of Breast Cancer Aggressiveness | 000 | 1 | NIH | 3/20/2024 | $47,404 |
| | 2024 | 2024 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA248048 | A novel determinant of prostate cancer growth | 000 | 4 | NIH | 3/1/2024 | $290,488 |
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