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 | Issue Date FY: 2025 ( Subtotal = $83,946,974 ) (Continued on the next page) |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23MD017284 | Improving Black sarcoidosis patients’ care with a collaboratively developed, patient centered program | 002 | 4 | NIH | 5/1/2025 | $159,992 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R00EY033909 | The role of neuronal activity on retinal angiogenesis and blood-retina barrier (BRB) maturation | 000 | 3 | NIH | 4/23/2025 | $248,999 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01GM130641 | Modeling Transition Metal Ion Binding to Proteins | 002 | 6 | NIH | 7/29/2025 | $329,648 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL172805 | Artificial sweeteners and cardiovascular disease | 000 | 1 | NIH | 3/4/2025 | $796,395 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AA027456 | Transcriptional and non-transcriptional function of IRF3 in ALD | 000 | 5 | NIH | 8/5/2025 | $555,449 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | T32EY024236 | Cole Eye Institute Vision Science Training Program | 000 | 10 | NIH | 7/31/2025 | $81,513 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | P50AA024333 | Alcohol and tissue injury, from mechanisms to treatments | 000 | 10 | NIH | 5/7/2025 | $1,665,498 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | DP1AI169444 | Defining the viral PTMome: Towards the development of novel antiviral approaches | 000 | 5 | NIH | 7/17/2025 | $1,127,000 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01EY024972 | Multi-organ protection from hyperoxia of the severely premature infant | 001 | 9 | NIH | 5/30/2025 | $402,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA222195 | The role of NUDT16 in DNA damage response and tumorigenesis | 001 | 7 | NIH | 7/30/2025 | $405,116 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL058758 | Molecular basis of ILK-mediated cell adhesion | 003 | 24 | NIH | 8/4/2025 | $55,040 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL058758 | Molecular basis of ILK-mediated cell adhesion | 002 | 24 | NIH | 3/20/2025 | $495,369 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R03EB034863 | Development of motion correction algorithms for functional MRI data using a custom simultaneously excited multi-slice MRI acquisition with prospectively injected motion | 000 | 1 | NIH | 1/21/2025 | $80,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01EY034755 | Inflammatory Signaling and Regeneration in Zebrafish models of Retinal Degeneration | 000 | 3 | NIH | 1/24/2025 | $515,193 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23AT012484 | A Daily, Digital Mindfulness-Based Intervention for Depressive Symptoms After Serious Illness | 000 | 1 | NIH | 3/24/2025 | $165,240 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | P30EY025585 | NEI Center Core Grant for Vision Research | 000 | 10 | NIH | 7/16/2025 | $644,002 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA300540 | Assessing feasibility of gastric cancer screening in the US | 000 | 1 | NIH | 3/20/2025 | $564,414 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AA031226 | Studying alcohol-associated liver disease and its interaction with rs738409 variant in PNPLA3 in a liver culture model | 000 | 2 | NIH | 7/24/2025 | $523,477 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS136997 | Neural Coding and Control of Pain Detection in Somatosensory Cortex | 000 | 1 | NIH | 3/28/2025 | $560,934 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23HL150279 | Novel Cardiac MRI-Based Predictors for Tetralogy of Fallot: Deformation, Kinematic, and Geometric Analyses | 000 | 5 | NIH | 1/28/2025 | $159,163 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K08HL168348 | Nocturnal hypoxemia dysregulates skeletal muscle protein homeostasis in COPD | 000 | 1 | NIH | 12/24/2024 | $151,578 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F31EY035133 | Characterizing the role of mitochondrial DNA mutations on retinal degeneration. | 001 | 2 | NIH | 7/31/2025 | $564 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | F31EY035133 | Characterizing the role of mitochondrial DNA mutations on retinal degeneration. | 000 | 2 | NIH | 1/14/2025 | $48,974 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG086247 | Improving colorectal cancer screening decisions through consideration of life expectancy | 000 | 1 | NIH | 12/31/2024 | $625,452 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35GM156762 | Synthetic biology tools and strategies to streamline the sensing and responding to disease cues in engineered theragnostic bacteria. | 000 | 1 | NIH | 12/26/2024 | $402,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01MH133584 | Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors | 001 | 1 | NIH | 4/21/2025 | $353,125 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01MH133584 | Lymphatic dysfunction in neurodevelopmental disorders and associated behaviors | 000 | 1 | NIH | 12/13/2024 | $241,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R21AI182702 | Modulation of Monocyte and T Cell Functions by Immune Inhibitory Receptors during Subclinical Malaria | 000 | 1 | NIH | 12/19/2024 | $184,109 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DE033391 | Molecular mechanism of Zika virus-induced premature craniofacial suture closure | 001 | 2 | NIH | 5/5/2025 | $40,250 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DE033391 | Molecular mechanism of Zika virus-induced premature craniofacial suture closure | 000 | 2 | NIH | 12/17/2024 | $362,250 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS137230 | Molecular Mechanism of Glucocorticoid Receptor, Cytochrome P450, and P-Glycoprotein Axis on Drug Regulation at the Blood-Brain Barrier in Epilepsy with Focal Cortical Dysplasia | 000 | 1 | NIH | 12/5/2024 | $431,676 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R37CA295609 | Molecular mediators of disparate outcomes experienced by patients of African ancestry with lung cancer | 000 | 1 | NIH | 12/4/2024 | $368,288 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K01NS136791 | Analysis of C9ORF72-associated poly (GR) interactions on BAF chromatin remodeling complex structure and function | 000 | 1 | NIH | 12/10/2024 | $236,668 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | K23ES035447 | Air Pollution, Environmental Injustice and Progressive Pulmonary Fibrosis | 000 | 1 | NIH | 12/12/2024 | $241,811 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS135080 | Molecular Profiling and Biomarkers of Memory Phenotypes in Temporal Lobe Epilepsy | 002 | 2 | NIH | 6/10/2025 | $577,978 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01DK132038 | Septins in intestinal fibrosis | 000 | 3 | NIH | 4/25/2025 | $630,078 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R34HL173138 | Evaluating Whether Treating Elevated Blood Pressure in the Inpatient Setting Impacts Patient Outcomes: the ACT-BP pilot | 000 | 1 | NIH | 7/18/2025 | $362,250 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124081 | lncRNA regulation of glioblastoma progression and therapeutic resistance | 001 | 4 | NIH | 7/23/2025 | $54,720 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01NS124081 | lncRNA regulation of glioblastoma progression and therapeutic resistance | 000 | 4 | NIH | 11/20/2024 | $492,501 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG078763 | Immune cell activation and associated blood brain barrier changes across different stages of Alzheimer's disease | 000 | 3 | NIH | 7/9/2025 | $738,231 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01CA257544 | Targeting TET DNA Dioxygenases as Therapeutic Principle in Myeloid Neoplasms | 000 | 5 | NIH | 7/3/2025 | $608,324 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R35NS127083 | Contribution of Myeloid-Derived Suppressor Cells to Neuro-Inflammatory Alterations and Disease Progression in Glioblastoma | 000 | 4 | NIH | 5/7/2025 | $654,737 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R61HL171747 | Development of a first-in-class complement inhibitor for treating complement-mediated hematologic diseases | 000 | 2 | NIH | 8/12/2025 | $563,500 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AI181758 | KSHV-mediated metabolic reprogramming for LANA expression and viral persistency | 000 | 2 | NIH | 5/9/2025 | $675,416 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL167831 | Gut microbial dietary phenylalanine metabolism and heart failure | 001 | 2 | NIH | 7/22/2025 | $79,005 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01HL167831 | Gut microbial dietary phenylalanine metabolism and heart failure | 000 | 2 | NIH | 1/13/2025 | $711,062 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG082382 | Novel oxidative pathway targets microglia in Alzheimer's disease | 000 | 2 | NIH | 4/21/2025 | $704,702 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R01AG082382 | Novel oxidative pathway targets microglia in Alzheimer's disease | 001 | 2 | NIH | 6/20/2025 | $62,640 |
| | 2025 | 2025 | CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE OF CASE WESTERN RESERVE UNIVERSITY | 9500 EUCLID AVE. | CLEVELAND | OH | 44195-0001 | CUYAHOGA | USA | R13AR083805 | Clinical Scholars Career Development Program (CSCDP) | 000 | 2 | NIH | 1/13/2025 | $30,000 |
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