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| | |
 | Issue Date FY: 2025 ( Subtotal = $443,776 ) |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180456 | What is the human antibody response to measles virus vaccination? | 000 | 2 | NIH | 11/6/2024 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180853 | Illuminating Lujo virus glycoprotein structure, receptor engagement and neutralizing antibody epitopes | 000 | 2 | NIH | 10/25/2024 | $221,888 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM128938 | Studying the function of human genetic variation in the light of 3D genome organization | 000 | 7 | NIH | 11/6/2024 | $0 |
|
| Issue Date FY: 2024 ( Subtotal = $55,603,074 ) (Continued on the next page) |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI150753 | Developing computational models to predict the immune response to B. pertussis booster vaccination | 000 | 5 | NIH | 2/14/2024 | $1,215,114 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 001 | 3 | NIH | 3/20/2024 | $445,252 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 003 | 3 | NIH | 5/16/2024 | $469,233 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI170010 | Dynamic analysis of beta cell attacks in response to virus infection in Human pancreatic slices | 001 | 2 | NIH | 5/23/2024 | $22,875 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 002 | 2 | NIH | 8/20/2024 | $293,085 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | T32AI125179 | Training in Immunological Mechanisms | 000 | 8 | NIH | 6/7/2024 | $328,919 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA247500 | Exploring the potential of TET inhibition in cancer immunotherapy | 000 | 5 | NIH | 6/14/2024 | $477,498 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA247500 | Exploring the potential of TET inhibition in cancer immunotherapy | 001 | 5 | NIH | 6/18/2024 | $99,352 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180456 | What is the human antibody response to measles virus vaccination? | 001 | 1 | NIH | 9/11/2024 | $27,450 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180456 | What is the human antibody response to measles virus vaccination? | 000 | 1 | NIH | 12/1/2023 | $247,050 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI163188 | Development of a Replicon RNA-based Vaccine against Dengue and Zika | 000 | 4 | NIH | 5/9/2024 | $721,849 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA256133 | Bioactive Metabolites Modulate Immune-Related Adverse Events in Cancer Immunotherapy | 000 | 4 | NIH | 6/20/2024 | $659,355 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI180196 | A novel strategy for vaccine-induced protection against maternal-to-fetal transmission of Zika virus | 001 | 1 | NIH | 9/3/2024 | $87,389 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI180196 | A novel strategy for vaccine-induced protection against maternal-to-fetal transmission of Zika virus | 000 | 1 | NIH | 6/7/2024 | $807,251 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM128938 | Studying the function of human genetic variation in the light of 3D genome organization | 002 | 7 | NIH | 9/10/2024 | $21,151 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180801 | Filovirus nucleocapsid assembly, caught in the act, by in situ structural biology | 001 | 1 | NIH | 9/11/2024 | $27,450 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180853 | Illuminating Lujo virus glycoprotein structure, receptor engagement and neutralizing antibody epitopes | 001 | 1 | NIH | 9/11/2024 | $27,450 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35CA210043 | The TET-DNMT-ASXL1-OGT axis: relevance to clonal hematopoiesis, heterochromatin integrity and cancer | 001 | 8 | NIH | 8/29/2024 | $1,098,000 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI040127 | Signal transduction and gene induction in lymphocytes | 000 | 32 | NIH | 8/15/2024 | $658,800 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI173884 | A novel CD4+ T cell subset associated with allergy protection | 001 | 2 | NIH | 8/1/2024 | -$203,750 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | AY1AX000055 | Strategic Herpesvirus Immune Evasion and Latency Defense (SHIELD) | 000 | 1 | NIH | 8/27/2024 | $31,104,137 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM128938 | Studying the function of human genetic variation in the light of 3D genome organization | 001 | 7 | NIH | 8/1/2024 | $494,100 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R61AI183471 | HIV mRNA vaccine strategies for efficient priming, diversity and durability of immune responses | 001 | 1 | NIH | 7/12/2024 | $0 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01DK135683 | Genetic studies linking LSP1 function in T cells to Inflammatory Bowel Disease | 001 | 2 | NIH | 5/16/2024 | $24,156 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI178427 | Structure of the SARS-CoV-2 Nucleocapsid: building block to viral capsid | 000 | 2 | NIH | 7/9/2024 | $229,720 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI173927 | Experimental identification of functional GWAS variants linked to COVID-19 severity in immune cells | 000 | 2 | NIH | 4/17/2024 | $274,500 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180801 | Filovirus nucleocapsid assembly, caught in the act, by in situ structural biology | 000 | 1 | NIH | 5/24/2024 | $247,050 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R37AI125068 | Maximizing germinal centers and somatic hypermutation to HIV Env immunogens | 001 | 9 | NIH | 5/23/2024 | $88,202 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI173884 | A novel CD4+ T cell subset associated with allergy protection | 000 | 2 | NIH | 6/6/2024 | $228,750 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI153500 | Maternal Antibody-Mediated Enhancement of Dengue Pathogenesis | 001 | 4 | NIH | 5/24/2024 | $56,838 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI143934 | The Role of Cytoplasmic and Nuclear THEMIS in Immature and Mature T cells | 001 | 5 | NIH | 5/28/2024 | $68,844 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI118626 | Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment | 003 | 10 | NIH | 5/27/2024 | $2,391,540 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM147554 | Elucidating the signaling and protein interaction networks of the O-GlcNAc transferase during embryonic stem cell state transitions | 000 | 3 | NIH | 5/8/2024 | $457,500 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM147554 | Elucidating the signaling and protein interaction networks of the O-GlcNAc transferase during embryonic stem cell state transitions | 001 | 3 | NIH | 5/9/2024 | $89,433 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA279795 | Proteome-wide base editor screens to assess phosphorylation site functionality in immunosenescence | 000 | 1 | NIH | 4/9/2024 | $573,738 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U24CA248138 | THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCE | 000 | 4 | NIH | 5/10/2024 | $813,113 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI109842 | NFAT, bZIP proteins, and transcriptional programs in lymphocytes | 001 | 36 | NIH | 5/29/2024 | $84,234 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R61AI183471 | HIV mRNA vaccine strategies for efficient priming, diversity and durability of immune responses | 000 | 1 | NIH | 4/1/2024 | $892,826 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI109842 | NFAT, bZIP proteins, and transcriptional programs in lymphocytes | 000 | 36 | NIH | 2/27/2024 | $758,119 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI153500 | Maternal Antibody-Mediated Enhancement of Dengue Pathogenesis | 000 | 4 | NIH | 2/22/2024 | $511,547 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01DK135683 | Genetic studies linking LSP1 function in T cells to Inflammatory Bowel Disease | 000 | 2 | NIH | 1/12/2024 | $362,340 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R37AI125068 | Maximizing germinal centers and somatic hypermutation to HIV Env immunogens | 000 | 9 | NIH | 1/9/2024 | $793,821 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI143934 | The Role of Cytoplasmic and Nuclear THEMIS in Immature and Mature T cells | 000 | 5 | NIH | 1/17/2024 | $619,602 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180853 | Illuminating Lujo virus glycoprotein structure, receptor engagement and neutralizing antibody epitopes | 000 | 1 | NIH | 11/24/2023 | $247,050 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI180152 | Dysregulation of TET dioxygenase function as a source of aberrant transposable element expression during human aging | 000 | 1 | NIH | 3/20/2024 | $658,800 |
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