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 | Issue Date FY: 2026 ( Subtotal = $10,700,306 ) |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI187062 | Towards a predictive understanding of influenza immunity through experimental data integration, iterative model development, and rigorous assessment of model quality | 000 | 2 | NIH | 1/2/2026 | $1,246,617 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA279795 | Proteome-wide base editor screens to assess phosphorylation site functionality in immunosenescence | 000 | 3 | NIH | 1/28/2026 | $503,641 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI189589 | Illuminating Immunoregulatory Mechanisms of Interleukin-1 Receptor 8 and Novel Therapeutic Strategies | 000 | 1 | NIH | 2/1/2026 | $890,877 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI189517 | House dust-mite allergen-specific T cell subsets in allergy and asthma | 000 | 1 | NIH | 3/27/2026 | $536,810 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI196080 | Development of a therapeutic antibody cocktail against New World Arenaviruses | 000 | 1 | NIH | 4/1/2026 | $923,708 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | K08AI196260 | Human upper airway immune memory kinetics and durability against respiratory pathogens | 000 | 1 | NIH | 4/2/2026 | $159,300 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI142742 | Human immune memory to COVID-19, vaccines, and respiratory pathogens | 000 | 8 | NIH | 4/1/2026 | $2,573,442 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01DK135683 | Genetic studies linking LSP1 function in T cells to Inflammatory Bowel Disease | 000 | 4 | NIH | 2/19/2026 | $402,600 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI180152 | Dysregulation of TET dioxygenase function as a source of aberrant transposable element expression during human aging | 000 | 3 | NIH | 2/9/2026 | $658,800 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R61AI183471 | HIV mRNA vaccine strategies for efficient priming, diversity and durability of immune responses | 000 | 3 | NIH | 3/30/2026 | $829,725 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R24OD038114 | Next Generation Crispr Ready, HLA Class I and II Transgenic Mouse Platform | 000 | 2 | NIH | 4/2/2026 | $692,868 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI196817 | Mapping anti-filovirus humoral immune responses in broadly seroreactive individuals | 000 | 1 | NIH | 4/1/2026 | $279,000 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI197006 | Defining function and regulation of the novel SLE-susceptibility gene ILRUN in T cells | 000 | 1 | NIH | 2/5/2026 | $476,436 |
| | 2026 | 2026 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI188119 | Deorphanizing a novel GPCR expressed by tissue resident memory cells | 000 | 1 | NIH | 2/18/2026 | $566,875 |
| | 2026 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R56AI187512 | The role of Alternaria fungal sensitization in asthma pathogenesis | 000 | 1 | NIH | 3/26/2026 | $0 |
| | 2026 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180853 | Illuminating Lujo virus glycoprotein structure, receptor engagement and neutralizing antibody epitopes | 000 | 2 | NIH | 3/4/2026 | $0 |
| | 2026 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | F31AI189334 | Roles of vaccine perturbations on germinal center dynamics | 000 | 1 | NIH | 1/12/2026 | -$40,393 |
| | 2026 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U24CA248138 | THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCE | 000 | 5 | NIH | 3/16/2026 | $0 |
| | 2026 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180456 | What is the human antibody response to measles virus vaccination? | 000 | 2 | NIH | 3/4/2026 | $0 |
| | 2026 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI178427 | Structure of the SARS-CoV-2 Nucleocapsid: building block to viral capsid | 000 | 2 | NIH | 12/18/2025 | $0 |
| | 2026 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA247500 | Exploring the potential of TET inhibition in cancer immunotherapy | 000 | 5 | NIH | 12/2/2025 | $0 |
| | 2026 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI128589 | Investigating the role of TET deficiency in promoting T cell expansion and inflammation | 000 | 8 | NIH | 1/21/2026 | $0 |
| | 2026 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI040127 | Signal transduction and gene induction in lymphocytes | 000 | 32 | NIH | 12/9/2025 | $0 |
| | 2026 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | AY1AX000055 | Strategic Herpesvirus Immune Evasion and Latency Defense (SHIELD) | 000 | 1 | NIH | 2/25/2026 | $0 |
| | 2026 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 000 | 2 | NIH | 12/29/2025 | $0 |
| | 2026 | 2023 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 001 | 2 | NIH | 2/26/2026 | $0 |
| | 2026 | 2023 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R24AI108564 | Research Resources: Epigenomic and Transcriptomic Profile of Human Immune Cells | 000 | 9 | NIH | 1/20/2026 | $0 |
| | 2026 | 2022 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 002 | 2 | NIH | 2/27/2026 | $0 |
|
| Issue Date FY: 2025 ( Subtotal = $26,007,184 ) (Continued on the next page) |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180456 | What is the human antibody response to measles virus vaccination? | 000 | 2 | NIH | 11/6/2024 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI142742 | Human immune memory to COVID-19, vaccines, and respiratory pathogens | 002 | 7 | NIH | 7/17/2025 | $2,576,765 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI187062 | Towards a predictive understanding of influenza immunity through experimental data integration, iterative model development, and rigorous assessment of model quality | 000 | 1 | NIH | 12/19/2024 | $1,246,617 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R37AI125068 | Maximizing germinal centers and somatic hypermutation to HIV Env immunogens | 000 | 10 | NIH | 1/17/2025 | $874,385 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI180196 | A novel strategy for vaccine-induced protection against maternal-to-fetal transmission of Zika virus | 000 | 2 | NIH | 5/2/2025 | $873,588 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35CA210043 | The TET-DNMT-ASXL1-OGT axis: relevance to clonal hematopoiesis, heterochromatin integrity and cancer | 000 | 9 | NIH | 9/11/2025 | $1,098,000 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01DK135683 | Genetic studies linking LSP1 function in T cells to Inflammatory Bowel Disease | 000 | 3 | NIH | 3/5/2025 | $362,340 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U24CA248138 | THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCE | 000 | 5 | NIH | 7/31/2025 | $851,522 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA279795 | Proteome-wide base editor screens to assess phosphorylation site functionality in immunosenescence | 001 | 2 | NIH | 9/24/2025 | $56,622 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA279795 | Proteome-wide base editor screens to assess phosphorylation site functionality in immunosenescence | 000 | 2 | NIH | 1/23/2025 | $509,593 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM147554 | Elucidating the signaling and protein interaction networks of the O-GlcNAc transferase during embryonic stem cell state transitions | 000 | 4 | NIH | 5/9/2025 | $457,500 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R24OD038114 | Next Generation Crispr Ready, HLA Class I and II Transgenic Mouse Platform | 000 | 1 | NIH | 4/23/2025 | $775,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM128938 | Studying the function of human genetic variation in the light of 3D genome organization | 001 | 8 | NIH | 8/21/2025 | $494,100 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI118626 | Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment | 002 | 11 | NIH | 8/25/2025 | $93,590 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI118626 | Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment | 001 | 11 | NIH | 8/15/2025 | $2,297,949 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI180152 | Dysregulation of TET dioxygenase function as a source of aberrant transposable element expression during human aging | 000 | 2 | NIH | 3/11/2025 | $639,037 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180800 | Understanding pH-dependent receptor utilization of Lassa virus | 000 | 2 | NIH | 3/11/2025 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R61AI183471 | HIV mRNA vaccine strategies for efficient priming, diversity and durability of immune responses | 000 | 2 | NIH | 4/1/2025 | $874,358 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180853 | Illuminating Lujo virus glycoprotein structure, receptor engagement and neutralizing antibody epitopes | 000 | 2 | NIH | 10/25/2024 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180801 | Filovirus nucleocapsid assembly, caught in the act, by in situ structural biology | 000 | 2 | NIH | 4/25/2025 | $228,750 |
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