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 | Issue Date FY: 2025 ( Subtotal = $28,533,766 ) (Continued on the next page) |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI153500 | Maternal Antibody-Mediated Enhancement of Dengue Pathogenesis | 000 | 5 | NIH | 3/6/2025 | $551,334 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 004 | 4 | NIH | 8/25/2025 | $350,000 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 005 | 4 | NIH | 8/25/2025 | $107,310 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 005 | 4 | NIH | 8/25/2025 | $350,000 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 003 | 4 | NIH | 7/16/2025 | $445,252 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 002 | 4 | NIH | 4/18/2025 | $3,020,173 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI128589 | Investigating the role of TET deficiency in promoting T cell expansion and inflammation | 001 | 9 | NIH | 6/10/2025 | $1,098,000 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | T32AI125179 | Training in Immunological Mechanisms | 000 | 9 | NIH | 8/29/2025 | $422,882 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R24AI108564 | Research Resources: Epigenomic and Transcriptomic Profile of Human Immune Cells | 000 | 10 | NIH | 9/4/2025 | $1,301,799 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI040127 | Signal transduction and gene induction in lymphocytes | 002 | 33 | NIH | 8/7/2025 | $1,976,400 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM128938 | Studying the function of human genetic variation in the light of 3D genome organization | 001 | 8 | NIH | 8/21/2025 | $494,100 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180456 | What is the human antibody response to measles virus vaccination? | 000 | 2 | NIH | 11/6/2024 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI142742 | Human immune memory to COVID-19, vaccines, and respiratory pathogens | 002 | 4 | NIH | 1/22/2025 | $2,576,765 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI142742 | Human immune memory to COVID-19, vaccines, and respiratory pathogens | 003 | 7 | NIH | 7/17/2025 | $2,576,765 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI187062 | Towards a predictive understanding of influenza immunity through experimental data integration, iterative model development, and rigorous assessment of model quality | 000 | 1 | NIH | 12/19/2024 | $1,246,617 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R37AI125068 | Maximizing germinal centers and somatic hypermutation to HIV Env immunogens | 000 | 10 | NIH | 1/17/2025 | $874,385 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI180196 | A novel strategy for vaccine-induced protection against maternal-to-fetal transmission of Zika virus | 000 | 2 | NIH | 5/2/2025 | $873,588 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35CA210043 | The TET-DNMT-ASXL1-OGT axis: relevance to clonal hematopoiesis, heterochromatin integrity and cancer | 000 | 9 | NIH | 9/11/2025 | $1,098,000 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180800 | Understanding pH-dependent receptor utilization of Lassa virus | 000 | 2 | NIH | 3/11/2025 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI180152 | Dysregulation of TET dioxygenase function as a source of aberrant transposable element expression during human aging | 000 | 2 | NIH | 3/11/2025 | $639,037 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R61AI183471 | HIV mRNA vaccine strategies for efficient priming, diversity and durability of immune responses | 000 | 2 | NIH | 4/1/2025 | $874,358 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U24CA248138 | THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCE | 000 | 5 | NIH | 7/31/2025 | $851,522 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI118626 | Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment | 002 | 11 | NIH | 8/25/2025 | $93,590 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI118626 | Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment | 001 | 11 | NIH | 8/15/2025 | $2,297,949 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01DK135683 | Genetic studies linking LSP1 function in T cells to Inflammatory Bowel Disease | 000 | 3 | NIH | 3/5/2025 | $362,340 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180853 | Illuminating Lujo virus glycoprotein structure, receptor engagement and neutralizing antibody epitopes | 000 | 2 | NIH | 10/25/2024 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180801 | Filovirus nucleocapsid assembly, caught in the act, by in situ structural biology | 000 | 2 | NIH | 4/25/2025 | $228,750 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA279795 | Proteome-wide base editor screens to assess phosphorylation site functionality in immunosenescence | 000 | 2 | NIH | 1/23/2025 | $509,593 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM147554 | Elucidating the signaling and protein interaction networks of the O-GlcNAc transferase during embryonic stem cell state transitions | 000 | 4 | NIH | 5/9/2025 | $457,500 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R56AI187512 | The role of Alternaria fungal sensitization in asthma pathogenesis | 000 | 1 | NIH | 4/28/2025 | $175,000 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | F31AI189334 | Roles of vaccine perturbations on germinal center dynamics | 001 | 1 | NIH | 7/1/2025 | $0 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | F31AI189334 | Roles of vaccine perturbations on germinal center dynamics | 000 | 1 | NIH | 6/5/2025 | $40,394 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R24OD038114 | Next Generation Crispr Ready, HLA Class I and II Transgenic Mouse Platform | 000 | 1 | NIH | 4/23/2025 | $775,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI163188 | Development of a Replicon RNA-based Vaccine against Dengue and Zika | 000 | 5 | NIH | 6/3/2025 | $721,849 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 004 | 4 | NIH | 8/25/2025 | $107,310 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA256133 | Bioactive Metabolites Modulate Immune-Related Adverse Events in Cancer Immunotherapy | 000 | 5 | NIH | 6/25/2025 | $693,716 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 004 | 4 | NIH | 8/25/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 001 | 3 | NIH | 4/8/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 000 | 3 | NIH | 3/25/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI128589 | Investigating the role of TET deficiency in promoting T cell expansion and inflammation | 000 | 8 | NIH | 6/9/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI109842 | NFAT, bZIP proteins, and transcriptional programs in lymphocytes | 000 | 36 | NIH | 5/22/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI040127 | Signal transduction and gene induction in lymphocytes | 001 | 32 | NIH | 8/7/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM128938 | Studying the function of human genetic variation in the light of 3D genome organization | 000 | 7 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI142742 | Human immune memory to COVID-19, vaccines, and respiratory pathogens | 001 | 6 | NIH | 1/22/2025 | $5,217 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | AY1AX000055 | Strategic Herpesvirus Immune Evasion and Latency Defense (SHIELD) | 000 | 1 | NIH | 4/10/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI143934 | The Role of Cytoplasmic and Nuclear THEMIS in Immature and Mature T cells | 000 | 5 | NIH | 5/23/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI150753 | Developing computational models to predict the immune response to B. pertussis booster vaccination | 000 | 5 | NIH | 7/1/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 005 | 2 | NIH | 4/7/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 003 | 2 | NIH | 3/27/2025 | $0 |
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