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 | Issue Date FY: 2025 ( Subtotal = $10,826,263 ) |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R37AI125068 | Maximizing germinal centers and somatic hypermutation to HIV Env immunogens | 000 | 10 | NIH | 1/17/2025 | $874,385 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180800 | Understanding pH-dependent receptor utilization of Lassa virus | 000 | 2 | NIH | 3/11/2025 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI180152 | Dysregulation of TET dioxygenase function as a source of aberrant transposable element expression during human aging | 000 | 2 | NIH | 3/11/2025 | $639,037 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R61AI183471 | HIV mRNA vaccine strategies for efficient priming, diversity and durability of immune responses | 000 | 2 | NIH | 4/1/2025 | $874,358 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180853 | Illuminating Lujo virus glycoprotein structure, receptor engagement and neutralizing antibody epitopes | 000 | 2 | NIH | 10/25/2024 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180801 | Filovirus nucleocapsid assembly, caught in the act, by in situ structural biology | 000 | 2 | NIH | 4/25/2025 | $228,750 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA279795 | Proteome-wide base editor screens to assess phosphorylation site functionality in immunosenescence | 000 | 2 | NIH | 1/23/2025 | $509,593 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM147554 | Elucidating the signaling and protein interaction networks of the O-GlcNAc transferase during embryonic stem cell state transitions | 000 | 4 | NIH | 5/9/2025 | $457,500 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R56AI187512 | The role of Alternaria fungal sensitization in asthma pathogenesis | 000 | 1 | NIH | 4/28/2025 | $175,000 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R24OD038114 | Next Generation Crispr Ready, HLA Class I and II Transgenic Mouse Platform | 000 | 1 | NIH | 4/23/2025 | $775,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI153500 | Maternal Antibody-Mediated Enhancement of Dengue Pathogenesis | 000 | 5 | NIH | 3/6/2025 | $551,334 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 002 | 4 | NIH | 4/18/2025 | $3,020,173 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180456 | What is the human antibody response to measles virus vaccination? | 000 | 2 | NIH | 11/6/2024 | $221,888 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI187062 | Towards a predictive understanding of influenza immunity through experimental data integration, iterative model development, and rigorous assessment of model quality | 000 | 1 | NIH | 12/19/2024 | $1,246,617 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01DK135683 | Genetic studies linking LSP1 function in T cells to Inflammatory Bowel Disease | 000 | 3 | NIH | 3/5/2025 | $362,340 |
| | 2025 | 2025 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI180196 | A novel strategy for vaccine-induced protection against maternal-to-fetal transmission of Zika virus | 000 | 2 | NIH | 5/2/2025 | $873,588 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 005 | 2 | NIH | 4/7/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 003 | 2 | NIH | 3/27/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI118626 | Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment | 000 | 10 | NIH | 2/20/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI173884 | A novel CD4+ T cell subset associated with allergy protection | 000 | 2 | NIH | 4/3/2025 | -$21,662 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R35GM128938 | Studying the function of human genetic variation in the light of 3D genome organization | 000 | 7 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 001 | 3 | NIH | 4/8/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01AI167892 | HIPC Data Coordinating Center | 000 | 3 | NIH | 3/25/2025 | $0 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI142742 | Functional and dysfunctional human CD4 T cell and B cell responses to bacteria and viruses | 001 | 6 | NIH | 1/22/2025 | $5,217 |
| | 2025 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | AY1AX000055 | Strategic Herpesvirus Immune Evasion and Latency Defense (SHIELD) | 000 | 1 | NIH | 4/10/2025 | $0 |
| | 2025 | 2023 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 004 | 2 | NIH | 4/7/2025 | $0 |
| | 2025 | 2023 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 002 | 2 | NIH | 3/27/2025 | $0 |
| | 2025 | 2023 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R37CA276779 | Evaluation of T follicular regulatory cells as novel cellular targets of cancer immunotherapy | 000 | 1 | NIH | 3/14/2025 | -$6,734 |
| | 2025 | 2023 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI092453 | Specificity, Phenotype and Function of Pancreatic CD8 T Cells in Human Type 1 Diabetes | 000 | 11 | NIH | 1/23/2025 | -$329,555 |
| | 2025 | 2023 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI163665 | Role of a Novel Interferon Responsive T Cell Subset in Allergy and Asthma | 000 | 2 | NIH | 3/25/2025 | -$70,013 |
| | 2025 | 2023 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI142742 | Functional and dysfunctional human CD4 T cell and B cell responses to bacteria and viruses | 000 | 5 | NIH | 1/22/2025 | -$5,217 |
| | 2025 | 2022 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 006 | 2 | NIH | 4/8/2025 | $0 |
| | 2025 | 2022 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 001 | 2 | NIH | 3/27/2025 | $0 |
| | 2025 | 2022 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI146042 | Histamine-Releasing Factor Oligomers in Food Allergy | 000 | 4 | NIH | 2/11/2025 | $0 |
| | 2025 | 2022 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01AI040127 | Signal transduction and gene induction in lymphocytes | 000 | 30 | NIH | 12/20/2024 | $0 |
| | 2025 | 2022 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U19AI142742 | Functional and dysfunctional human CD4 T cell and B cell responses to bacteria and viruses | 002 | 4 | NIH | 1/22/2025 | $0 |
| | 2025 | 2022 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R03OD034494 | Using Common Fund datasets for prioritization of disease-associated genetic variants | 000 | 1 | NIH | 12/30/2024 | $0 |
| | 2025 | 2022 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01DE028227 | Stimulating Neo-Antigen Specific T Cell Responses in Head and Neck Cancers | 000 | 5 | NIH | 4/7/2025 | $0 |
| | 2025 | 2020 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U01CA260588 | SARS-CoV-2-reactive tissue-resident memory T cells in healthy and cancer subjects | 000 | 1 | NIH | 3/13/2025 | $0 |
|
| Issue Date FY: 2024 ( Subtotal = $55,603,074 ) (Continued on the next page) |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R01CA247500 | Exploring the potential of TET inhibition in cancer immunotherapy | 001 | 5 | NIH | 6/18/2024 | $99,352 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | U24CA248138 | THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCE | 000 | 4 | NIH | 5/10/2024 | $813,113 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180800 | Understanding pH-dependent receptor utilization of Lassa virus | 001 | 1 | NIH | 9/11/2024 | $27,450 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI173884 | A novel CD4+ T cell subset associated with allergy protection | 001 | 2 | NIH | 8/1/2024 | -$203,750 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI173884 | A novel CD4+ T cell subset associated with allergy protection | 000 | 2 | NIH | 6/6/2024 | $228,750 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI178427 | Structure of the SARS-CoV-2 Nucleocapsid: building block to viral capsid | 000 | 2 | NIH | 7/9/2024 | $229,720 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180801 | Filovirus nucleocapsid assembly, caught in the act, by in situ structural biology | 001 | 1 | NIH | 9/11/2024 | $27,450 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180801 | Filovirus nucleocapsid assembly, caught in the act, by in situ structural biology | 000 | 1 | NIH | 5/24/2024 | $247,050 |
| | 2024 | 2024 | LA JOLLA INSTITUTE FOR IMMUNOLOGY | 9420 ATHENA CIR | LA JOLLA | CA | 92037-1387 | SAN DIEGO | USA | R21AI180853 | Illuminating Lujo virus glycoprotein structure, receptor engagement and neutralizing antibody epitopes | 001 | 1 | NIH | 9/11/2024 | $27,450 |
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