Thursday, November 21, 2024 11/21/2024

The Johns Hopkins University-Blantyre Clinical Trials Unit

Award Number: UM1AI069518
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By:

View Award Abstract

Project Summary Sub-Saharan Africa continues to bear a disproportionate burden of the global HIV epidemic. Conducting studies in the most affected areas of the world is critical to the international HIV research agenda. The Johns Hopkins University-Blantyre, Malawi Clinical Trials Unit (JHU Blantyre-CTU) and its clinical research site (CRS) in Malawi, located in one of the most affected regions of the world, propose to continue and expand high- impact research collaborations with four NIAID Clinical Research Networks in order to prevent, treat, manage and potentially cure HIV and AIDS in adults, key populations, and children. With more than 30 years of HIV research experience and the strong backing of the host institutions (Johns Hopkins University and College of Medicine, University of Malawi), the CTU and CRS leadership will be responsible for the conduct and management of clinical trials at the Blantyre, CRS in accordance with the Research Networks and NIAID policies. The CTU aims to advance the scientific agenda of the proposed Clinical Research Networks for HIV prevention, treatment and vaccine research among adults and children by generating hypotheses and developing new scientific concepts; continuing implementation of active study protocols at the Blantyre CRS under the current CTU; making available the efficient and flexible local research infrastructure to quickly respond to emerging needs of the Networks; and by engaging protocol-specific populations. The CTU will emphasize quality, oversight, cohesiveness and efficiency in all operations as it works to achieve these aims. During the current CTU cycle (2013 to present), the Blantyre CRS has been involved in 35 studies at various stages, from initiation to completion, for four existing Division of AIDS/NIAID Clinical Research Networks. The CRS has established effective institutional and community collaborations and has been responsive to both the Network agendas and the national health research agenda for Malawi. The goal of this application is to describe scientific, leadership and administrative strengths of the proposed JHU-Blantyre CTU and its CRS in Blantyre, Malawi, which will ensure successful implementation of the NIAID international clinical research agenda. The sub-sections (A-L) of this application provide a scientific overview of the proposed CTU and describe its administrative and financial management structures; plans for communication, evaluation and training; and the roles, responsibilities and resources of each CTU element and CRS technical department, including community engagement, pharmacy, laboratory, quality and regulatory assurance, and data management. Our CTU arrangement that encompasses a single CRS has demonstrated capacity and promotes efficiency.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $602,598 )
2025	2025	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	19	11/6/2024	NON-COMPETING CONTINUATION	$758,076
2025	2020	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	14	10/1/2024	NON-COMPETING CONTINUATION	-$155,478
														Subtotal = $602,598

Issue Date FY: 2024 ( Subtotal = $1,877,925 )
2024	2024	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	18	11/2/2023	NON-COMPETING CONTINUATION	$877,563
2024	2024	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	18	6/4/2024	NON-COMPETING CONTINUATION	$877,562
2024	2024	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	18	6/4/2024	SUPPLEMENT FOR EXPANSION	$122,800
														Subtotal = $1,877,925

Issue Date FY: 2023 ( Subtotal = $2,412,151 )
2023	2023	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	17	11/16/2022	NON-COMPETING CONTINUATION	$1,160,480
2023	2023	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	17	7/11/2023	NON-COMPETING CONTINUATION	$1,251,671
														Subtotal = $2,412,151

Issue Date FY: 2022 ( Subtotal = $2,814,014 )
2022	2022	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	16	6/23/2022	NON-COMPETING CONTINUATION	$1,232,213
2022	2022	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	16	11/16/2021	NON-COMPETING CONTINUATION	$1,581,801
2022	2022	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	16	11/23/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,814,014

Issue Date FY: 2021 ( Subtotal = $2,626,268 )
2021	2021	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	003	15	6/30/2021	COMPETING CONTINUATION	$1,116,588
2021	2021	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	15	11/25/2020	COMPETING CONTINUATION	$1,509,680
2021	2021	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	15	4/21/2021	COMPETING CONTINUATION	$45,268
2021	2020	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	14	4/21/2021	NON-COMPETING CONTINUATION	-$45,268
														Subtotal = $2,626,268

Issue Date FY: 2020 ( Subtotal = $3,220,822 )
2020	2020	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	14	6/3/2020	NON-COMPETING CONTINUATION	$1,610,410
2020	2020	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	14	2/19/2020	NON-COMPETING CONTINUATION	$0
2020	2020	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	14	11/20/2019	NON-COMPETING CONTINUATION	$1,610,412
														Subtotal = $3,220,822

Issue Date FY: 2019 ( Subtotal = $3,745,637 )
2019	2019	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	13	11/21/2018	NON-COMPETING CONTINUATION	$1,828,890
2019	2019	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	13	5/21/2019	NON-COMPETING CONTINUATION	$1,916,747
2019	2019	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	13	3/15/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,745,637

Issue Date FY: 2018 ( Subtotal = $2,002,921 )
2018	2018	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	003	12	8/21/2018	NON-COMPETING CONTINUATION	$99,736
2018	2018	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	12	12/1/2017	NON-COMPETING CONTINUATION	$634,395
2018	2018	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	12	5/14/2018	NON-COMPETING CONTINUATION	$732,671
2018	2018	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	12	2/14/2018	NON-COMPETING CONTINUATION	$536,119
														Subtotal = $2,002,921

Issue Date FY: 2017 ( Subtotal = $1,860,643 )
2017	2017	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	11	8/9/2017	NON-COMPETING CONTINUATION	$0
2017	2017	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	11	2/1/2017	NON-COMPETING CONTINUATION	$11,834
2017	2017	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	003	11	8/18/2017	NON-COMPETING CONTINUATION	$0
2017	2017	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	11	11/15/2016	NON-COMPETING CONTINUATION	$1,848,809
														Subtotal = $1,860,643

Issue Date FY: 2016 ( Subtotal = $1,179,653 )
2016	2016	JOHNS HOPKINS UNIVERSITY	1101 E 33RD STREET, STE-C-210	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	10	11/18/2015	NON-COMPETING CONTINUATION	$1,179,653
														Subtotal = $1,179,653

Issue Date FY: 2015 ( Subtotal = $227,616 )
2015	2015	JOHNS HOPKINS UNIVERSITY	1101 E 33RD STREET, STE-C-210	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	9	8/14/2015	NON-COMPETING CONTINUATION	$59,446
2015	2015	JOHNS HOPKINS UNIVERSITY	1101 E 33RD STREET, STE-C-210	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	9	11/14/2014	NON-COMPETING CONTINUATION	$168,170
														Subtotal = $227,616

Issue Date FY: 2014 ( Subtotal = $3,714,154 )
2014	2014	JOHNS HOPKINS UNIVERSITY	1101 E 33RD STREET, STE-C-210	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	8	12/10/2013	COMPETING CONTINUATION	$773,207
2014	2014	JOHNS HOPKINS UNIVERSITY	1101 E 33RD STREET, STE-C-210	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	001	8	12/26/2013	COMPETING CONTINUATION	$2,571,865
2014	2014	JOHNS HOPKINS UNIVERSITY	1101 E 33RD STREET, STE-C-210	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	8	2/14/2014	COMPETING CONTINUATION	$369,082
														Subtotal = $3,714,154

Issue Date FY: 2013 ( Subtotal = $8,980,285 ) (Continued on the next page)
2013	2013	JOHNS HOPKINS UNIVERSITY	CHARLES & 34TH STREETS	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	002	7	5/31/2013	NON-COMPETING CONTINUATION	$1,285,385
2013	2013	JOHNS HOPKINS UNIVERSITY	CHARLES & 34TH STREETS	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	000	7	11/28/2012	NON-COMPETING CONTINUATION	$7,145,600
2013	2013	JOHNS HOPKINS UNIVERSITY	CHARLES & 34TH STREETS	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Allergy and Infectious Diseases Research	003	7	8/9/2013	NON-COMPETING CONTINUATION	$0
Grand Total All Awards = $40,729,442

Page 1 of 2 (56 items)12

Top

All Categories

About

Search

Reports

Data Submission

Award Information

The Johns Hopkins University-Blantyre Clinical Trials Unit

Award Number: UM1AI069518

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer