Wednesday, February 5, 2025 2/5/2025

Chicago Clinical Trials Unit

Award Number: UM1AI069471
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Parent Award Project Summary The Chicago Clinical Trials Unit (CCTU) is a consortium of five Clinical Research Sites (CRSs) which will address three priority clinical research areas of the NIAID: 1) adult HIV therapeutic strategies including HIV cure, noninfectious comorbidities, and infectious co-morbidities of hepatitis and tuberculosis; 2) vaccines to prevent HIV; and 3) integrated HIV prevention strategies. The CCTU consists of five highly experienced and scientifically productive CRSs that are uniquely positioned to develop, implement and adapt the clinical research priorities of the NIAID clinical research priority areas. The CCTU has a proven track record and will continue its productivity through active engagement with a diverse host of at risk and HIV-impacted communities, participation in high impact, ground-breaking clinical research studies, efficient management of resources and critical performance oversight of the clinical activities, laboratories, and pharmacies. The CCTU includes CRSs and personnel that have long term and productive involvement with three of the research networks; the fourth-antibacterial resistance-being a new network in this consortium. The CRSs and their network affiliations include: Northwestern University (adult HIV therapeutic strategies); University of Illinois Chicago (vaccines to prevent HIV, integrated HIV prevention), Rush University (adult HIV therapeutic strategies), University of Chicago (integrated HIV prevention strategies) and Trinity Health & Wellness Center (adult HIV therapeutic strategies). Four of the CRSs are located in Chicago, an ethnically and racially diverse urban area of 9.5 million persons that is the third largest metropolitan region in the United States and one of the major urban HIV epicenters. The aims of this proposal are: development, implementation and adaptation of the clinical research program of the 1) Adult HIV Therapeutics Strategy Network, 2) the Vaccines to Prevent HIV Network, 3) the Integrated HIV Prevention Strategies Network, and 4) Bidirectional engagement of the relevant and at risk HIV-infected/impacted communities with the CCTU clinical researchers. The CCTU is well positioned to reach diverse populations and contribute significantly to the NIAID research agenda.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $507,116 )
2025	2025	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	19	11/19/2024	NON-COMPETING CONTINUATION	$507,116
														Subtotal = $507,116

Issue Date FY: 2024 ( Subtotal = $1,052,787 )
2024	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	18	11/2/2023	NON-COMPETING CONTINUATION	$526,591
2024	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	003	18	8/26/2024	NON-COMPETING CONTINUATION	$0
2024	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	002	18	6/11/2024	NON-COMPETING CONTINUATION	$526,590
2024	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	14	4/30/2024	SUPPLEMENT FOR EXPANSION	-$394
														Subtotal = $1,052,787

Issue Date FY: 2023 ( Subtotal = $697,341 )
2023	2023	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	17	6/14/2023	NON-COMPETING CONTINUATION	$566,019
2023	2023	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	17	11/16/2022	NON-COMPETING CONTINUATION	$131,322
														Subtotal = $697,341

Issue Date FY: 2022 ( Subtotal = $1,185,973 )
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	16	11/19/2021	NON-COMPETING CONTINUATION	$723,444
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	002	16	6/14/2022	NON-COMPETING CONTINUATION	$462,529
2022	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	14	5/19/2022	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,185,973

Issue Date FY: 2021 ( Subtotal = $1,284,164 )
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	002	15	5/21/2021	COMPETING CONTINUATION	$642,082
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	004	15	8/30/2021	COMPETING CONTINUATION	$68,816
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	15	11/19/2020	COMPETING CONTINUATION	$642,082
2021	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	003	14	8/30/2021	NON-COMPETING CONTINUATION	-$68,816
2021	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	14	4/22/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,284,164

Issue Date FY: 2020 ( Subtotal = $2,929,144 )
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	14	6/9/2020	NON-COMPETING CONTINUATION	$1,041,255
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	002	14	6/17/2020	SUPPLEMENT FOR EXPANSION	$814,136
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	14	11/21/2019	NON-COMPETING CONTINUATION	$1,073,753
														Subtotal = $2,929,144

Issue Date FY: 2019 ( Subtotal = $2,093,731 )
2019	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	13	11/20/2018	NON-COMPETING CONTINUATION	$1,046,866
2019	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	13	5/20/2019	NON-COMPETING CONTINUATION	$1,046,865
														Subtotal = $2,093,731

Issue Date FY: 2018 ( Subtotal = $1,491,481 )
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	12	2/16/2018	NON-COMPETING CONTINUATION	$248,581
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	002	12	5/22/2018	NON-COMPETING CONTINUATION	$745,740
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	12	11/24/2017	NON-COMPETING CONTINUATION	$497,160
														Subtotal = $1,491,481

Issue Date FY: 2017 ( Subtotal = $1,297,285 )
2017	2017	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	11	11/17/2016	NON-COMPETING CONTINUATION	$1,297,285
														Subtotal = $1,297,285

Issue Date FY: 2016 ( Subtotal = $1,491,481 )
2016	2016	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	10	11/13/2015	NON-COMPETING CONTINUATION	$1,491,481
														Subtotal = $1,491,481

Issue Date FY: 2015 ( Subtotal = $1,450,349 )
2015	2015	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	9	11/18/2014	NON-COMPETING CONTINUATION	$1,450,349
														Subtotal = $1,450,349

Issue Date FY: 2014 ( Subtotal = $2,057,977 )
2014	2014	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	8	12/20/2013	COMPETING CONTINUATION	$512,448
2014	2014	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	002	8	3/12/2014	COMPETING CONTINUATION	$193,267
2014	2014	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	8	12/10/2013	COMPETING CONTINUATION	$1,352,262
														Subtotal = $2,057,977

Issue Date FY: 2013 ( Subtotal = $2,665,678 )
2013	2013	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	7	4/17/2013	NON-COMPETING CONTINUATION	$297,308
2013	2013	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	003	7	8/15/2013	NON-COMPETING CONTINUATION	$100,000
2013	2013	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	002	7	6/24/2013	NON-COMPETING CONTINUATION	$227,013
2013	2013	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	7	12/5/2012	NON-COMPETING CONTINUATION	$2,041,357
														Subtotal = $2,665,678

Issue Date FY: 2012 ( Subtotal = $2,628,944 )
2012	2012	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	000	6	12/22/2011	NON-COMPETING CONTINUATION	$2,191,822
2012	2012	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	002	6	8/22/2012	NON-COMPETING CONTINUATION	$193,588
2012	2012	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Allergy and Infectious Diseases Research	001	6	2/29/2012	NON-COMPETING CONTINUATION	$243,534
														Subtotal = $2,628,944

Grand Total All Awards = $22,833,451

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Chicago Clinical Trials Unit

Award Number: UM1AI069471

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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