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DURBAN INTERNATIONAL CLINICAL TRIALS UNIT

Award Number: UM1AI069426
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/01/2007
PERIOD OF PERFORMANCE END DATE: 11/30/2013

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DURBAN INTERNATIONAL CLINICAL TRIALS UNIT - This Durban CTU application is underpinned by a central administrative hub that serves the 3 HIV clinic research sites included in this application. They bring together 3 major disciplines, most affected by the rising morbidity and mortality from HIV/AIDS viz. adult medicine, pediatrics, and obstetrics and gynecology from the University of KwaZulu-Natal, to develop and promote research into translational drug research, optimization of clinical management and co-morbidities and to complement prevention and vaccine research programs in the region. The principal investigator Prof. Umesh Lalloo (also site leader for the Adult HIV Research Clinic)is supported by site experienced site leaders for the other reseach clinics proposed. Administration, Pharmacy, Lab Services and Data Management are the shared resources for all three sites.The long-term objectives are to: 1. Promote development of new strategies (drugs, immunomodulation, and regimens) to simplify the complex treatment of HIV/AIDS, given the immense impact of the epidemic in resource limited settings. This will ensure optimal treatment options in a Clade C HIV epidemic and where the threat of ARV drug resistance is serious and drug interactions are important, given the multiple comorbidities 2. Promote the development of optimal strategies to treatment the complications of HIV, which contributes to the rising morbidity and mortality 3. Promote the development of scientific and clinical research expertise in resource limited settings in individuals from previously disadvantaged groups


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2013 ( Subtotal = $600,000 )
2013	2013	UNIVERSITY OF KWAZULU-NATAL	UNIVERSITY ROAD CHILTERN HILLS	DURBAN				ZAF	Allergy and Infectious Diseases Research	006	8	7/19/2013	EXTENSION WITH OR WITHOUT FUNDS	$600,000
2013	2012	UNIVERSITY OF KWAZULU-NATAL	UNIVERSITY ROAD CHILTERN HILLS	DURBAN				ZAF	Allergy and Infectious Diseases Research	000	7	11/27/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$1,154,244
2013	2012	UKZN INNOVATION (PTY) LTD	20 KINGS MEAD BOULEVARD	DURBAN		4013		ZAF	Allergy and Infectious Diseases Research	002	6	12/10/2012	NON-COMPETING CONTINUATION	$0
2013	2012	UNIVERSITY OF KWAZULU-NATAL	UNIVERSITY ROAD CHILTERN HILLS	DURBAN				ZAF	Allergy and Infectious Diseases Research	001	7	11/30/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,154,244
2013	2012	UNIVERSITY OF KWAZULU-NATAL	UNIVERSITY ROAD CHILTERN HILLS	DURBAN		3629		ZAF	Allergy and Infectious Diseases Research	003	7	2/19/2013	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2013	2012	UNIVERSITY OF KWAZULU-NATAL	UNIVERSITY ROAD CHILTERN HILLS	DURBAN		3629		ZAF	Allergy and Infectious Diseases Research	005	7	4/11/2013	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2013	2012	UNIVERSITY OF KWAZULU-NATAL	UNIVERSITY ROAD CHILTERN HILLS	DURBAN		3629		ZAF	Allergy and Infectious Diseases Research	004	7	2/28/2013	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $600,000

Issue Date FY: 2012 ( Subtotal = $1,913,012 )
2012	2012	UKZN INNOVATION (PTY) LTD	69 FRANCOIS ROAD ROOM 054	DURBAN				ZAF	Allergy and Infectious Diseases Research	003	6	8/10/2012	NON-COMPETING CONTINUATION	-$758,766
2012	2012	UNIVERSITY OF KWAZULU-NATAL	PAEDIATRICS & CHILD HEALTH	CONGELLA				ZAF	Allergy and Infectious Diseases Research	006	7	9/19/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2012	2012	UKZN INNOVATION (PTY) LTD	69 FRANCOIS ROAD ROOM 054	DURBAN				ZAF	Allergy and Infectious Diseases Research	001	6	2/2/2012	NON-COMPETING CONTINUATION	-$395,478
2012	2012	UKZN INNOVATION (PTY) LTD	69 FRANCOIS ROAD ROOM 054	DURBAN				ZAF	Allergy and Infectious Diseases Research	000	6	1/30/2012	NON-COMPETING CONTINUATION	$1,913,012
2012	2012	UNIVERSITY OF KWAZULU-NATAL	UNIVERSITY ROAD CHILTERN HILLS	DURBAN				ZAF	Allergy and Infectious Diseases Research	004	7	8/10/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$758,766
2012	2012	UNIVERSITY OF KWAZULU-NATAL	UNIVERSITY ROAD CHILTERN HILLS	DURBAN				ZAF	Allergy and Infectious Diseases Research	005	7	8/21/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$395,478
2012	2012	UKZN INNOVATION (PTY) LTD	20 KINGS MEAD BOULEVARD	DURBAN		4013		ZAF	Allergy and Infectious Diseases Research	002	6	3/19/2012	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,913,012

Grand Total All Awards = $2,513,012

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DURBAN INTERNATIONAL CLINICAL TRIALS UNIT

Award Number: UM1AI069426

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/01/2007

PERIOD OF PERFORMANCE END DATE: 11/30/2013

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