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The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve Health

Award Number: UL1TR003015
ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SOCIAL SERVICES
PERIOD OF PERFORMANCE START DATE: 02/27/2019
PERIOD OF PERFORMANCE END DATE: 09/30/2025

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The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve Health - The integrated Translational Health Research Institute of Virginia (iTHRIV) program is a collaboration of public and private institutions across the Commonwealth of Virginia that brings team science, innovation, and a commitment to train the next generation of clinical and translational researchers. Our three iTHRIV partners include University of Virginia (Central VA), Virginia Tech Carilion (Southwestern VA) and Inova Health Systems (Northern VA). Our two iTHRIV affiliates are the Center for Open Science and the Licensing and Ventures Group in Charlottesville. A particular strength of iTHRIV lies in integrating data science approaches through all aspects of clinical translational research in order to speed discovery and improve the health of our communities. iTHRIV has a central tenant that serves as the organizing principle: health care solutions are hidden in underutilized data. Our overall goal is to deepen the iTHRIV infrastructure to support clinical translational research to benefit the diverse rural and urban populations that iTHRIV member clinicians serve. The unified approach across the components of this CTSA application is to integrate data and data analytics to accelerate and streamline scientific workflows for clinical trials, innovative therapeutic advancements, and the creation of more personalized approaches to healthcare. Data science is a particular strength of our team and will allow us to transform our cross-state informatics infrastructure by creating The Commons, a scalable research hosting platform shared by iTHRIV partners that will serve as the foundation for our informatics support. It will provide the infrastructure for the Research Concierge Services, the human and electronic approach to supporting clinical translational research. This platform will combine data-centered approaches to discovery by hosting and sharing datasets, applications, and other research objects with a human-centered approach to design and systems architecture. The Commons is designed to serve both as a technical framework and an approach to establishing processes and tools necessary to enable data sharing between partner locations. The Concierge service informs and connects researchers to training, support services and compliance resources to streamline the clinical translational research process. The mission of iTHRIV, through the Commons and the Concierge Services, is to remove barriers to discovery in Virginia and beyond. The iTHRIV Commons is conceptually similar to the NIH Data Commons, and the implementation of this framework across partner sites will remove barriers to data access and other research objects (algorithms, best practices, etc.), while enforcing compliance in the secure use of data. iTHRIV will marry the expertise of our world class data science teams in The Commons to our outstanding clinical translational researchers in order to uncover health care solutions.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = -$269 )
2026	2023	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 EMMET ST N	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	000	5	2/18/2026	NON-COMPETING CONTINUATION	-$269
														Subtotal = -$269

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 EMMET ST N	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	000	5	1/7/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 EMMET ST N	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	000	5	5/1/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $3,119,742 )
2023	2023	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	000	5	2/28/2023	NON-COMPETING CONTINUATION	$3,119,870
2023	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 EMMET ST N	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	001	3	6/22/2023	SUPPLEMENT FOR EXPANSION	-$128
														Subtotal = $3,119,742

Issue Date FY: 2022 ( Subtotal = $3,800,384 )
2022	2022	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	001	4	5/5/2022	NON-COMPETING CONTINUATION	$380,037
2022	2022	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	000	4	1/29/2022	NON-COMPETING CONTINUATION	$3,420,347
														Subtotal = $3,800,384

Issue Date FY: 2021 ( Subtotal = $4,436,701 )
2021	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	002	3	2/20/2021	SUPPLEMENT FOR EXPANSION	$50,000
2021	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	006	3	8/27/2021	SUPPLEMENT FOR EXPANSION	$169,903
2021	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	003	3	2/23/2021	NON-COMPETING CONTINUATION	$0
2021	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	005	3	3/18/2021	SUPPLEMENT FOR EXPANSION	$414,928
2021	2021	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	001	3	2/6/2021	NON-COMPETING CONTINUATION	$3,801,870
2021	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	000	2	10/21/2020	SUPPLEMENT FOR EXPANSION	$0
2021	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	004	2	3/17/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $4,436,701

Issue Date FY: 2020 ( Subtotal = $4,798,629 )
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	001	2	2/1/2020	NON-COMPETING CONTINUATION	$3,570,330
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	006	2	8/19/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	004	2	7/2/2020	SUPPLEMENT FOR EXPANSION	$50,000
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	007	2	8/20/2020	SUPPLEMENT FOR EXPANSION	$414,928
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	003	2	6/24/2020	NON-COMPETING CONTINUATION	$0
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	008	2	8/31/2020	SUPPLEMENT FOR EXPANSION	$483,575
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	005	2	8/11/2020	SUPPLEMENT FOR EXPANSION	$161,500
2020	2020	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	002	2	5/29/2020	SUPPLEMENT FOR EXPANSION	$118,296
2020	2019	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	000	1	12/3/2019	NEW	$0
														Subtotal = $4,798,629

Issue Date FY: 2019 ( Subtotal = $4,130,473 )
2019	2019	RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA	1001 N EMMET ST	CHARLOTTESVILLE	VA	22903	CHARLOTTESVILLE CITY	USA	National Center for Advancing Translational Sciences	000	1	2/27/2019	NEW	$4,130,473
														Subtotal = $4,130,473

Grand Total All Awards = $20,285,660

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The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve Health

Award Number: UL1TR003015

ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SOCIAL SERVICES

PERIOD OF PERFORMANCE START DATE: 02/27/2019

PERIOD OF PERFORMANCE END DATE: 09/30/2025

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