Wednesday, February 5, 2025 2/5/2025

Yale Clinical and Translational Science Award

Award Number: UL1TR001863
ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SOCIAL SERVICES

Group Awards By:

View Award Abstract

Contact PD/PI: Smith, Brian Richard 1. Overall: Project Summary The Yale Center for Clinical Investigation (YCCI) was created in 2005 to advance Yale's clinical research mission. One year later, YCCI became the home of the Yale CTSA. At YCCIs inception, Yale was a national leader in T0-T2 translational research, basic/translational science training, and it supported distinctive fellowship programs such as the Robert Wood Johnson Clinical Scholars Program. Since then, the CTSA has had a transformative impact linking diverse components of the Yale community in T1-T4 research, providing the central infrastructure for the effective conduct of ethical, innovative, rigorous, and reproducible research, and in training the next generation of research leaders. By any metric of scale, breadth, quality, and impact, both the CTSA's research enterprise and its educational mission have been enormously successful for Yale. This renewal application does not simply seek to maintain excellence, but to enable YCCI to drive the continued transformation of the Yale T1-T4 translational research mission and its predoctoral and postdoctoral training mission and to promote collaboration across CTSA hubs. First, it will support informatics and computational advances that drive the emergence of a learning health system. In so doing, it will draw on the Yale New Haven Health System, a six-hospital 2,681-bed consortium that provides more than 2.4 million outpatient visits from patients from upper Westchester county, throughout Connecticut, and southern Rhode Island. It will also prepare young scientists to draw on this infrastructure to conduct research that influences the future of healthcare. Second, it will support technological and scientific advances in areas that will support the emergence of personalized healthcare, including multi-omics and imaging. YCCI will provide pilot grant support and training to foster the development of research careers and research teams that can deepen our insights into pathophysiology and build toward personalized treatments. Third, it will engage a broader and more diverse group of faculty, trainees, and community representatives to collaborate in the mission of addressing healthcare disparities that constitute a major burden on patients, their families, and on public health. To support this mission, YCCI will also foster the development of careers in community-based research from a diverse group of young investigators and enhance the overall clinical research workforce.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	9	1/7/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $10,948,828 )
2024	2024	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	001	9	5/23/2024	SUPPLEMENT FOR EXPANSION	$211,109
2024	2024	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	002	9	8/1/2024	NON-COMPETING CONTINUATION	$0
2024	2024	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	9	5/16/2024	NON-COMPETING CONTINUATION	$10,737,719
														Subtotal = $10,948,828

Issue Date FY: 2023 ( Subtotal = $11,171,009 )
2023	2023	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	003	8	7/21/2023	SUPPLEMENT FOR EXPANSION	$223,529
2023	2023	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	002	8	7/20/2023	SUPPLEMENT FOR EXPANSION	$209,852
2023	2023	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	001	8	7/12/2023	NON-COMPETING CONTINUATION	$10,737,719
2023	2023	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	005	8	8/31/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2023	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	004	8	7/27/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2020	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	5	11/21/2022	NON-COMPETING CONTINUATION	-$91
														Subtotal = $11,171,009

Issue Date FY: 2022 ( Subtotal = $11,007,964 )
2022	2022	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	004	7	6/6/2022	NON-COMPETING CONTINUATION	$10,737,719
2022	2022	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	005	7	6/16/2022	SUPPLEMENT FOR EXPANSION	$232,490
2022	2022	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	003	6	3/30/2022	SUPPLEMENT FOR EXPANSION	$37,755
2022	2022	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	006	7	8/12/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	002	6	12/14/2021	COMPETING CONTINUATION	$0
2022	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	001	6	11/7/2021	COMPETING CONTINUATION	$416,389
2022	2020	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	5	11/7/2021	NON-COMPETING CONTINUATION	-$416,389
														Subtotal = $11,007,964

Issue Date FY: 2021 ( Subtotal = $10,511,192 )
2021	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	6	6/1/2021	COMPETING CONTINUATION	$10,511,192
														Subtotal = $10,511,192

Issue Date FY: 2020 ( Subtotal = $8,408,317 )
2020	2020	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	001	5	6/15/2020	NON-COMPETING CONTINUATION	$8,408,317
2020	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	3	11/19/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $8,408,317

Issue Date FY: 2019 ( Subtotal = $8,657,777 )
2019	2019	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	005	4	9/19/2019	NON-COMPETING CONTINUATION	$0
2019	2019	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	004	4	8/16/2019	NON-COMPETING CONTINUATION	$8,657,777
2019	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	003	3	4/17/2019	NON-COMPETING CONTINUATION	$0
2019	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	002	3	11/17/2018	SUPPLEMENT FOR EXPANSION	$0
2019	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	001	3	10/25/2018	NON-COMPETING CONTINUATION	$0
2019	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	3	10/25/2018	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $8,657,777

Issue Date FY: 2018 ( Subtotal = $9,546,825 )
2018	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	001	3	9/11/2018	SUPPLEMENT FOR EXPANSION	$236,343
2018	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	3	8/9/2018	NON-COMPETING CONTINUATION	$9,310,482
														Subtotal = $9,546,825

Issue Date FY: 2017 ( Subtotal = $9,525,614 )
2017	2017	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	002	2	8/22/2017	SUPPLEMENT FOR EXPANSION	$523,250
2017	2017	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Trans-NIH Research Support	004	2	9/21/2017	SUPPLEMENT FOR EXPANSION	$335,000
2017	2017	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	003	2	9/8/2017	NON-COMPETING CONTINUATION	$503,648
2017	2017	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	2	6/15/2017	NON-COMPETING CONTINUATION	$7,894,476
2017	2017	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	001	2	7/26/2017	SUPPLEMENT FOR EXPANSION	$269,240
														Subtotal = $9,525,614

Issue Date FY: 2016 ( Subtotal = $8,409,297 )
2016	2016	YALE UNIVERSITY	47 College Street	NEW HAVEN	CT	06520	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	1	7/1/2016	NEW	$8,409,297
														Subtotal = $8,409,297

Grand Total All Awards = $88,186,823

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Yale Clinical and Translational Science Award

Award Number: UL1TR001863

ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SOCIAL SERVICES

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