Thursday, September 18, 2025 9/18/2025

Managing Hypertension Among People Living with HIV: an Integrated Model (MAP-IT)

Award Number: UH3HL154498
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/20/2020
PERIOD OF PERFORMANCE END DATE: 08/31/2026

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Managing Hypertension Among People Living with HIV: an Integrated Model (MAP-IT) - This proposal is a collaboration between University of Abuja, FHI 360, New York University and Saint Louis University. Access to antiretroviral drugs has led to increased survival of people living with HIV (PLWH), who now experience higher CVD-mortality than the general population, largely due to increased HTN burden. Global Burden of Disease reported a 95% increase in HTN-related mortality in Nigeria from 1990 to 2015. Thus, strategies to control HTN in PLWH are sorely needed. Physician shortage and poor access limit Nigeria’s capacity to control HTN in primary health centers (PHCs), where most PLWH receive care. Access to care and task-shifting of duties to nurses may mitigate these barriers. In 2011, FHI 360 initiated a USAID-funded program, Strengthening Integrated Delivery of HIV-AIDS Services (SIDHAS), which provides universal access to HIV services for over 190,000 PLWH in Nigeria . In a cluster RCT of 32 health centers in Ghana, we showed that a nurse-led task-shifting strategy for HTN control (TASSH), based on the WHO CVD Risk Package, led to a 34% greater systolic BP reduction than health insurance coverage alone (U01HL114198; PI: Ogedegbe). TASSH includes CV risk assessment; medication titration; and patient lifestyle counseling. The existence of an effective HIV chronic are platform (SIDHAS) and a well-proven evidence-based intervention for HTN control (TASSH) provides a unique opportunity for implementation of TASSH as an integrated NCD-HIV model for HTN control in PLWH. However, PHCs in Nigeria [with its weak healthcare system] lack the expertise needed to coordinate multilevel system changes. An implementation strategy to overcome this barrier is PF via provision of external expertise and support for addressing challenges in implementing evidence-based care. Although PF has been widely utilized in high income countries, its role in translating EBIs into routine practice in Africa has not been tested. FHI 360’s SIDHAS program and the 47 PHCs it supports in Akwa Ibom – [the state with the highest HIV burden in Nigeria] - provide a viable HIV chronic care platform for implementing TASSH as an integrated model for HTN control in PLWH. We will conduct this study in two phases using a mixed-methods design: 1) a UG3 planning phase that will use Promoting Action on Research in Health Services (PARiHS) to develop a context- specific PF strategy to implement, and facilitate integration of TASSH into an HIV chronic care platform (SIDHAS) for management of HTN in PLWH; and 2) a UH3 implementation phase that will use Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) to evaluate, in a stepped-wedge cluster RCT of 30 PHCs in 960 PLWH with uncontrolled HTN, the effect of PF on levels of TASSH adoption (primary outcome); BP control (co-primary outcome); and levels of TASSH sustainment (secondary outcome) at 18 months. We will also examine adoption and implementation fidelity of TASSH as potential mechanisms that may explain the impact of PF on BP control. The PF strategy comprises: (a) an advisory board that will provide leadership support for TASSH implementation; and (b) trained nurses (practice facilitators) who will serve as coaches, provide support, knowledge exchange and performance feedback to the nurses who will deliver TASSH at the PHCs.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	UNIVERSITY OF ABUJA	ORMER 2 MINI CAMPUS, UND ST.	GWAGWALADA				NGA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	000	5	8/11/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $497,488 )
2024	2024	UNIVERSITY OF ABUJA	ORMER 2 MINI CAMPUS, UND ST.	GWAGWALADA				NGA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	001	5	9/13/2024	NON-COMPETING CONTINUATION	$478,537
2024	2022	UNIVERSITY OF ABUJA	ORMER 2 MINI CAMPUS, UND ST.	GWAGWALADA				NGA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	000	3	10/24/2023	EXTENSION WITH OR WITHOUT FUNDS	$18,951
														Subtotal = $497,488

Issue Date FY: 2023 ( Subtotal = $825,652 )
2023	2023	UNIVERSITY OF ABUJA	UNIVERSITY ROAD, GWAGWALADA	ABUJA				NGA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	002	4	8/29/2023	SUPPLEMENT FOR EXPANSION	$188,674
2023	2023	UNIVERSITY OF ABUJA	UNIVERSITY ROAD, GWAGWALADA	ABUJA				NGA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	001	4	8/21/2023	NON-COMPETING CONTINUATION	$636,978
2023	2022	UNIVERSITY OF ABUJA	UNIVERSITY ROAD, GWAGWALADA	ABUJA				NGA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	000	3	12/12/2022	EXTENSION WITH OR WITHOUT FUNDS	$0
														Subtotal = $825,652

Issue Date FY: 2022 ( Subtotal = $635,499 )
2022	2022	UNIVERSITY OF ABUJA	UNIVERSITY ROAD, GWAGWALADA	ABUJA	NULL			NGA	Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders	000	3	9/15/2022	EXTENSION WITH OR WITHOUT FUNDS	$635,499
														Subtotal = $635,499

Grand Total All Awards = $1,958,639

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Managing Hypertension Among People Living with HIV: an Integrated Model (MAP-IT)

Award Number: UH3HL154498

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/20/2020

PERIOD OF PERFORMANCE END DATE: 08/31/2026

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