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A Dental implant registry of treatment outcomes of implant therapy by practitioners in the National Dental Practice Based Research Network

Award Number: UH3DE030090
ORGANIZATION: NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/01/2021
PERIOD OF PERFORMANCE END DATE: 05/31/2026

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A Dental implant registry of treatment outcomes of implant therapy by practitioners in the National Dental Practice Based Research Network - Protocol Title: A dental implant registry of treatment outcomes of implant therapy by practitioners in the National Dental Practice Based Research Network Summary There is a substantial body of literature to support that biological and prosthetic complications occur which may interfere with the health of the peri-implant tissues, the function and esthetics of the implant restoration. Peri- implant diseases are classified into peri-implant mucositis, inflammation restricted to the peri-implant mucosa, and peri-implantitis, characterized by peri-implant bone loss. The limitations of the current body of literature of biologic and prosthetic complications are based on many small studies and in large part conducted in an academic and specialty setting. We propose to create an implant registry within the National Dental Practice Based Research Network (NDPBRN) that will record the setting and implant therapy, the implants used, the prosthetic therapy provided and the rate of complications. The registry will create an opportunity for subsequent, additional targeted studies on specific complications available from the registry data and will lead to diagnosis driven therapy strategies. The target enrollment is a total of 2000 implants with prosthesis across the whole network. The one year UG3 Phase will be used to create a strategy to be able to meet the recruitment and enrollment objectives and to develop the protocol for data collection to facilitate the data gathering of the practitioners for the subjects they enroll. The data collection model we propose will be designed to be validated, concise, and easy to use for practitioners. We will develop a web based decision tree that will guide the practitioner through the data collection. The UH3 phase will recruit practitioners with representation of all 6 regions of the network that will enroll subjects with 2000 implants. Data collection will be detailed and comprehensive and will include surgical, prosthetic, and biologic aspects of implant therapy and radiographs for bone level assessments for a period of 3 years. The data will present clinically meaningful information about the prevalence of the various implant therapies, the incidence of prosthetic and biologic implant complications, risk factors for implant complications and evidence-based implant therapy strategies in every dental practices. We expect that the results from this study will significantly impact the clinical practice of implant dentistry and the quality of care provided for the patients.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $434,379 )
2025	2025	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	002	5	5/9/2025	NON-COMPETING CONTINUATION	$43,438
2025	2025	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	001	5	12/19/2024	NON-COMPETING CONTINUATION	$390,941
2025	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	000	4	12/12/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $434,379

Issue Date FY: 2024 ( Subtotal = $425,692 )
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	000	4	2/16/2024	NON-COMPETING CONTINUATION	$390,941
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	002	4	8/29/2024	NON-COMPETING CONTINUATION	$0
2024	2024	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	001	4	6/19/2024	NON-COMPETING CONTINUATION	$34,751
														Subtotal = $425,692

Issue Date FY: 2023 ( Subtotal = $462,393 )
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	001	3	2/21/2023	NON-COMPETING CONTINUATION	$434,379
2023	2023	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	003	3	8/30/2023	NON-COMPETING CONTINUATION	$0
2023	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	000	2	1/26/2023	EXTENSION WITH OR WITHOUT FUNDS	$0
2023	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH STREET	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	002	2	4/24/2023	EXTENSION WITH OR WITHOUT FUNDS	$28,014
														Subtotal = $462,393

Issue Date FY: 2022 ( Subtotal = $722,411 )
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	000	2	2/1/2022	EXTENSION WITH OR WITHOUT FUNDS	$729,707
2022	2022	UNIVERSITY OF ALABAMA AT BIRMINGHAM	701 S 20TH ST	BIRMINGHAM	AL	35294	JEFFERSON	USA	Oral Diseases and Disorders Research	001	2	4/20/2022	EXTENSION WITH OR WITHOUT FUNDS	-$7,296
														Subtotal = $722,411

Grand Total All Awards = $2,044,875

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A Dental implant registry of treatment outcomes of implant therapy by practitioners in the National Dental Practice Based Research Network

Award Number: UH3DE030090

ORGANIZATION: NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/01/2021

PERIOD OF PERFORMANCE END DATE: 05/31/2026

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