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Tele-Collaborative Outreach to Rural Patients with Chronic Pain: The CORPs Trial

Award Number: UH3AT012257
ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/14/2022
PERIOD OF PERFORMANCE END DATE: 08/31/2025

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Tele-Collaborative Outreach to Rural Patients with Chronic Pain: The CORPs Trial - Project Summary The overall goal of this multisite, pragmatic, randomized clinical trial is to adapt and test a tele-collaborative care intervention for chronic pain with veterans living in rural areas. During the 1-year UG3 phase, we will apply evidence-based quality improvement strategies to adapt our tele-collaborative pain care intervention for implementation across four geographically diverse VA health care facilities; pilot test and refine recruitment, intervention and data collection protocols at study sites; and, in collaboration with the Pain Management Collaboratory Coordinating Center, develop standard operating procedures for all activities to be conducted in the UH3 clinical trial phase. Engagement panels will inform adaptation of the intervention and all components of the methods of the clinical trial. During the 4-year UH3 phase, we will implement and evaluate the intervention among rural veterans with high impact chronic pain in a 12-month pragmatic effectiveness trial. We plan to recruit 152 veterans from each of four clinical sites (total N=608), diverse in terms of birth sex, race, and ethnicity. Participants will be randomized to receive either tele-collaborative pain care or minimally enhanced usual care. The intervention is based on the collaborative care model and includes an initial biopsychosocial chronic pain assessment with a nurse care manager, follow-up, and participation in a pain education group. The nurse care manager will receive consultation from a pain physician and participants may be referred for nonpharmacologic and complementary and integrative health treatments for chronic pain. The nurse care manager will also follow up with rural veterans and help them navigate care across VA and community health services. We hypothesize that rural veterans who receive tele-collaborative pain care, relative to minimally enhanced usual care, will evidence decreased pain severity and interference, increased physical functioning and quality of life, decreased mental health symptom severity and suicidal ideation and behavior, improved sleep, and increased utilization of nonpharmacologic and complementary and integrative health pain treatments. We further hypothesize that treatment effects will persist across female vs. male rural veterans and those who identify as white non-Hispanic vs. minoritized race or ethnicity. Finally, we will conduct an implementation process evaluation and an incremental cost-effectiveness analysis to inform development of an implementation toolkit. Study results will inform the future rollout of tele-collaborative pain care for rural veterans nationally.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2027 ( Subtotal = $278,410 )
2027	2024	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	3	10/13/2026	NON-COMPETING CONTINUATION	$278,410
														Subtotal = $278,410

Issue Date FY: 2026 ( Subtotal = -$278,410 )
2026	2024	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	3	8/21/2026	NON-COMPETING CONTINUATION	-$278,410
														Subtotal = -$278,410

Issue Date FY: 2025 ( Subtotal = $2,525,095 )
2025	2025	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	002	4	8/13/2025	EXTENSION WITH OR WITHOUT FUNDS	$2,525,095
2025	2024	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	3	6/25/2025	NON-COMPETING CONTINUATION	$0
2025	2024	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	001	3	7/30/2025	NON-COMPETING CONTINUATION	$0
2025	2024	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	003	3	8/14/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,525,095

Issue Date FY: 2024 ( Subtotal = $1,427,196 )
2024	2024	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	003	3	9/4/2024	NON-COMPETING CONTINUATION	$1,304,577
2024	2023	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	2	1/9/2024	EXTENSION WITH OR WITHOUT FUNDS	$0
2024	2023	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	002	2	3/20/2024	EXTENSION WITH OR WITHOUT FUNDS	$122,619
2024	2023	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	001	2	1/19/2024	EXTENSION WITH OR WITHOUT FUNDS	$0
														Subtotal = $1,427,196

Issue Date FY: 2023 ( Subtotal = $1,368,003 )
2023	2023	OREGON HEALTH & SCIENCE UNIVERSITY	3181 SW SAM JACKSON PARK RD	PORTLAND	OR	97239	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	2	9/15/2023	EXTENSION WITH OR WITHOUT FUNDS	$1,368,003
														Subtotal = $1,368,003

Grand Total All Awards = $5,320,294

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Tele-Collaborative Outreach to Rural Patients with Chronic Pain: The CORPs Trial

Award Number: UH3AT012257

ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/14/2022

PERIOD OF PERFORMANCE END DATE: 08/31/2025

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