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Environmental influences on Child Health Outcomes in the Northern Plains PASS-ECHO Cohort

Award Number: UG3OD023279
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/21/2016
PERIOD OF PERFORMANCE END DATE: 05/31/2025

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Environmental influences on Child Health Outcomes in the Northern Plains PASS-ECHO Cohort - PROJECT SUMMARY This proposal serves to leverage the Safe Passage Study ECHO (PASS ECHO) research infrastructure that has recruited a large cohort of ECHO mother/child pairs (n=6.647) for continued follow-up, as well as continued enrollment of new pregnancies and initiating a preconception cohort. The success of the PASS ECHO research team from 2016-2023, both in scientific collaboration and completing of operational tasks, provides an excellent foundation for increased enrollment and retention of ECHO participants, including a large proportion of rural and American Indian participants. PASS ECHO has a specialization in the ECHO Obesity health outcome. The following specific aims relate directly to advancing collaborative ECHO Cohort science and completing operational tasks relevant for successful participation in the next phase of ECHO. (SA1) Examine the effects of prenatal allostatic load, and its biomarkers, on childhood obesity and neurodevelopment. (SA2) Examine the independent and joint effects of prenatal life-style related exposures on child obesity-related outcomes, and how nutrition may impact these relationships. (SA3) Build upon demonstrated successful strategies and strong community/participant relationships to implement the ECHO-wide protocol v3.0 with deliberate efforts to increase participation in American Indian and rural communities.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $6,372,599 )
2024	2024	AVERA MCKENNAN	1325 S CLIFF AVE	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	002	10	5/21/2024	NON-COMPETING CONTINUATION	$6,134,134
2024	2023	AVERA MCKENNAN	1325 S CLIFF AVE	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	000	9	4/1/2024	COMPETING CONTINUATION	$238,465
2024	2023	AVERA MCKENNAN	1325 S CLIFF AVE	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	001	9	5/15/2024	COMPETING CONTINUATION	$0
														Subtotal = $6,372,599

Issue Date FY: 2023 ( Subtotal = $6,450,023 )
2023	2023	AVERA MCKENNAN	1325 S CLIFF AVE	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	001	9	9/7/2023	COMPETING CONTINUATION	$0
2023	2023	AVERA MCKENNAN	1325 S CLIFF AVE	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	000	9	8/16/2023	COMPETING CONTINUATION	$6,450,023
														Subtotal = $6,450,023

Issue Date FY: 2019 ( Subtotal = -$1,259,691 )
2019	2017	AVERA MCKENNAN HOSPITAL & UNIVERSITY CENTER	1325 S CLIFF AVE	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	000	3	2/5/2019	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$1,259,691
														Subtotal = -$1,259,691

Issue Date FY: 2018 ( Subtotal = -$295,600 )
2018	2017	SANFORD RESEARCH	2301 E 60TH ST N	SIOUX FALLS	SD	57104	MINNEHAHA	USA	Trans-NIH Research Support	000	2	1/30/2018	NON-COMPETING CONTINUATION	-$3,043,260
2018	2017	AVERA MCKENNAN HOSPITAL & UNIVERSITY CENTER	1325 S CLIFF AVE	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	001	3	1/30/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$2,747,660
2018	2017	AVERA MCKENNAN HOSPITAL & UNIVERSITY CENTER	1325 S CLIFF AVE	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	004	3	4/23/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$644,873
2018	2017	SANFORD RESEARCH	2301 E 60TH ST N	SIOUX FALLS	SD	57104	MINNEHAHA	USA	Trans-NIH Research Support	003	2	4/23/2018	NON-COMPETING CONTINUATION	-$526,189
2018	2016	SANFORD RESEARCH	2301 E 60TH ST N	SIOUX FALLS	SD	57104	MINNEHAHA	USA	Trans-NIH Research Support	002	1	4/23/2018	NEW	-$118,684
														Subtotal = -$295,600

Issue Date FY: 2017 ( Subtotal = $3,569,449 )
2017	2017	SANFORD RESEARCH	2301 E 60TH ST N	SIOUX FALLS	SD	57104	MINNEHAHA	USA	Trans-NIH Research Support	000	2	8/30/2017	NON-COMPETING CONTINUATION	$3,569,449
														Subtotal = $3,569,449

Issue Date FY: 2016 ( Subtotal = $1,646,232 )
2016	2016	SANFORD RESEARCH/USD	1100 EAST 21ST STREET	SIOUX FALLS	SD	57105	MINNEHAHA	USA	Trans-NIH Research Support	000	1	9/21/2016	NEW	$1,646,232
														Subtotal = $1,646,232

Grand Total All Awards = $16,483,012

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Environmental influences on Child Health Outcomes in the Northern Plains PASS-ECHO Cohort

Award Number: UG3OD023279

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/21/2016

PERIOD OF PERFORMANCE END DATE: 05/31/2025

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