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Maternal-Fetal Medicine Unit (MFMU) Network Clinical Centers

Award Number: UG1HD087230
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2016
PERIOD OF PERFORMANCE END DATE: 03/31/2030

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Maternal-Fetal Medicine Unit (MFMU) Network Clinical Centers - The purpose of this proposal is to demonstrate the capabilities of the University of Pittsburgh to continue to participate as a clinical site in the Eunice Kennedy Shriver NICHD Maternal-Fetal Medicine Units Network (MFMUN). We are particularly well suited to be a clinical site in this Network because of our delivery volume; clinical research infrastructure and track record; basic and translational experience and expertise; and specialized resources that we can bring to the Network. Approximately 10,000 women deliver per year at Magee-Womens Hospital, and 75% of these women initiate prenatal care in our system at < 14 weeks. Our site, a large volume delivery-perinatal center under a unified administrative structure, is ideal for participation in the MFMU Network. Through our extensive research infrastructure, we have successfully enrolled women as early as the first trimester, followed them longitudinally through pregnancy to delivery, conducted randomized clinical interventions, and have performed serial collection and processing of biological samples and ultrasound data. We also have demonstrated success in longitudinal postnatal maternal and neonatal follow-up. The demography of our population allows us to contribute uniquely to the study of preterm birth and other adverse pregnancy outcomes. Additionally, our site brings unique content and technical expertise in clinical obstetrics, fetal imaging, genomics and proteomics, placental pathology, and epidemiology. All these areas are represented among our faculty, and we have a long and successful history of research collaboration, within our institution and via multicenter studies. In this application, we aim to: 1. To describe our experience, infrastructure, and track record of participation in single- center and multicenter studies of adverse pregnancy outcomes 2. To demonstrate our ability to enroll a diverse patient population and demonstrate our ability to continue to enroll and provide maternal and newborn follow-up to subjects for ongoing and new MFMU studies 3. To delineate our unique suitability in terms of technical and multidisciplinary content expertise to address the objectives of the MFMU Network.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $302,549 )
2025	2025	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3240 CRAFT PL STE 100	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	003	10	3/28/2025	NON-COMPETING CONTINUATION	$302,549
2025	2024	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3240 CRAFT PL STE 100	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	002	9	2/12/2025	NON-COMPETING CONTINUATION	$0
2025	2023	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3240 CRAFT PL STE 100	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	001	8	1/8/2025	COMPETING CONTINUATION	$11,975
2025	2022	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3240 CRAFT PL STE 100	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	7	1/8/2025	NON-COMPETING CONTINUATION	-$11,975
														Subtotal = $302,549

Issue Date FY: 2024 ( Subtotal = $310,295 )
2024	2024	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3240 CRAFT PL STE 100	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	001	9	4/1/2024	NON-COMPETING CONTINUATION	-$31,029
2024	2024	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3240 CRAFT PL STE 100	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	9	3/22/2024	NON-COMPETING CONTINUATION	$310,295
2024	2024	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3240 CRAFT PL STE 100	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	002	9	4/30/2024	NON-COMPETING CONTINUATION	$31,029
														Subtotal = $310,295

Issue Date FY: 2023 ( Subtotal = $333,119 )
2023	2023	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	003	8	3/31/2023	COMPETING CONTINUATION	$333,119
2023	2022	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	001	7	12/12/2022	NON-COMPETING CONTINUATION	$0
2023	2022	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	002	7	3/8/2023	NON-COMPETING CONTINUATION	$0
2023	2022	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	7	11/30/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $333,119

Issue Date FY: 2022 ( Subtotal = $314,567 )
2022	2022	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	003	7	4/18/2022	NON-COMPETING CONTINUATION	$314,130
2022	2021	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	002	6	2/1/2022	COMPETING CONTINUATION	$0
2022	2021	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	001	6	11/23/2021	COMPETING CONTINUATION	$5,887
2022	2020	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	004	5	9/26/2022	NON-COMPETING CONTINUATION	$437
2022	2020	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	5	11/23/2021	NON-COMPETING CONTINUATION	-$5,887
														Subtotal = $314,567

Issue Date FY: 2021 ( Subtotal = $301,002 )
2021	2021	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	001	6	3/29/2021	COMPETING CONTINUATION	$338,980
2021	2021	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	002	6	5/17/2021	COMPETING CONTINUATION	-$37,978
2021	2020	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	5	11/18/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $301,002

Issue Date FY: 2020 ( Subtotal = $272,008 )
2020	2020	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	5	3/20/2020	NON-COMPETING CONTINUATION	$272,008
														Subtotal = $272,008

Issue Date FY: 2019 ( Subtotal = $272,008 )
2019	2019	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	4	3/27/2019	NON-COMPETING CONTINUATION	$272,008
														Subtotal = $272,008

Issue Date FY: 2018 ( Subtotal = $272,008 )
2018	2018	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	002	3	7/23/2018	NON-COMPETING CONTINUATION	$0
2018	2018	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	001	3	5/1/2018	NON-COMPETING CONTINUATION	$27,201
2018	2018	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	003	3	8/28/2018	NON-COMPETING CONTINUATION	$0
2018	2018	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	3	3/10/2018	NON-COMPETING CONTINUATION	$244,807
														Subtotal = $272,008

Issue Date FY: 2017 ( Subtotal = $272,008 )
2017	2017	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	001	2	6/13/2017	NON-COMPETING CONTINUATION	$27,201
2017	2017	MAGEE-WOMENS RESEARCH INSTITUTE AND FOUNDATION	3339 WARD ST	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	2	3/3/2017	NON-COMPETING CONTINUATION	$244,807
														Subtotal = $272,008

Issue Date FY: 2016 ( Subtotal = $286,758 )
2016	2016	MAGEE-WOMENS HEALTH CORPORATION	300 HALKET STREET	PITTSBURGH	PA	15213	ALLEGHENY	USA	Child Health and Human Development Extramural Research	000	1	3/28/2016	NEW	$286,758
														Subtotal = $286,758

Grand Total All Awards = $2,936,322

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Maternal-Fetal Medicine Unit (MFMU) Network Clinical Centers

Award Number: UG1HD087230

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2016

PERIOD OF PERFORMANCE END DATE: 03/31/2030

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