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Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research Unit

Award Number: UG1HD078439
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY Although there have been improvements in the under age five mortality rate (U5MR) and neonatal mortality rate (NMR) in Indian children, the burden of death in this population is still one live births to deaths. To achieve the United Nations Sustainable Development Goals for the U5MR and NMR rate, there is still an urgent need for improvement in pre-pregnancy through childhood care in India and globally. The overarching goal of Boston University (BU) and Lata Medical Research Foundation's (LMRF) Global Network (GN) for Women's and Children's Health Research Unit (RU) is to continue to collaborate with other GN RUs on research to improve health outcomes for women and children in low- and lower middle-income countries (LMIC). We have had a GN RU in Nagpur, India continuously since 2008. Our RU is in the eastern part of the State of Maharashtra (center of India) where NMR and infant mortality rates are higher than the overall rates in the state and many other parts of India. Our RU involves a partnership between multiple Schools and Departments (particularly Global Health, Obstetrics, Pediatrics, and Infectious Diseases) at Boston University and the academic medical institutional consortium led by the LMRF in Nagpur, that provides clinical, research expertise and infrastructure support. Since 2008, our RU has been successfully implementing studies, by patient and public involvement and engagement strategy, that exemplify Global Network's goals to conduct high-impact clinical trials and observational studies of sustainable, cost-effective health interventions and their implementation in women and children in LMICs, and building sustainable professional capacity and infrastructure for infectious diseases (maternal and pediatric), obstetric, neonatal and pediatric research. In the current cycle of the GN, we have participated in all common protocols, and have maintained high recruitment and retention rates. We have led 5 research initiatives, including developing a new socioeconomic status index, and studying the risk of maternal, fetal and neonatal adverse outcomes associated with exposure to household air pollution, Caesarian Section delivery and Maternal Depression. We have also had a leadership role in the Azithromycin trial sub-study on risk of acquiring Azithromycin resistance using novel microbiome, metagenomics and whole genome sequencing approaches, which required helping develop lab capacity in several GN sites. We have jointly and successfully mentored 20 junior faculty, fellows and students who have led site specific and GN wide publications. continue growth and development of the Nagpur RU, advance the research network in the region, and sustain the research infrastructure for the design and conduct of public health research in the Nagpur academic institutions; strengthen research focused on the leading causes of morbidity and mortality in pregnancy and early childhood in the GN and in the Nagpur area by public and patient engagement; and continue to identify and address gaps in maternal and child research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	12	10/31/2023	COMPETING CONTINUATION	$0
2024	2023	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	002	12	1/3/2024	COMPETING CONTINUATION	$1
2024	2023	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	003	12	1/10/2024	COMPETING CONTINUATION	$0
2024	2022	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	001	11	1/3/2024	NON-COMPETING CONTINUATION	-$1
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $622,651 )
2023	2023	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	003	12	9/21/2023	COMPETING CONTINUATION	$0
2023	2023	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	004	12	9/27/2023	COMPETING CONTINUATION	$0
2023	2023	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	002	12	8/1/2023	COMPETING CONTINUATION	$622,651
2023	2022	TRUSTEES OF BOSTON UNIVERSITY	85 EAST NEWTON ST # M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	001	11	7/24/2023	NON-COMPETING CONTINUATION	$0
2023	2022	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	11	6/9/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $622,651

Issue Date FY: 2022 ( Subtotal = $615,978 )
2022	2022	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	11	5/10/2022	NON-COMPETING CONTINUATION	$615,978
														Subtotal = $615,978

Issue Date FY: 2021 ( Subtotal = $615,978 )
2021	2021	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	10	5/28/2021	NON-COMPETING CONTINUATION	$615,978
														Subtotal = $615,978

Issue Date FY: 2020 ( Subtotal = $615,978 )
2020	2020	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	9	6/1/2020	NON-COMPETING CONTINUATION	$615,978
														Subtotal = $615,978

Issue Date FY: 2019 ( Subtotal = $615,978 )
2019	2019	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	001	8	6/10/2019	NON-COMPETING CONTINUATION	$615,978
2019	2018	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	7	10/23/2018	COMPETING CONTINUATION	$0
														Subtotal = $615,978

Issue Date FY: 2018 ( Subtotal = $632,228 )
2018	2018	TRUSTEES OF BOSTON UNIVERSITY	85 E NEWTON ST M-921	BOSTON	MA	02118	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	7	8/1/2018	COMPETING CONTINUATION	$632,228
														Subtotal = $632,228

Grand Total All Awards = $3,718,791

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Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research Unit

Award Number: UG1HD078439

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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