Monday, June 30, 2025 6/30/2025

NICHD Cooperative Multicenter Neonatal Research Network

Award Number: UG1HD053109
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/05/2006
PERIOD OF PERFORMANCE END DATE: 03/31/2030

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NICHD Cooperative Multicenter Neonatal Research Network - Project Summary The University of Iowa submits this renewal application for continued participation in the NICHD Neonatal Research Network (RFA-HD-23-002). We seek to continue to support the mission of the NRN to improve healthcare and outcomes for newborns, seeking solutions to increase survival without neurodevelopmental impairment or chronic illness for premature and critically ill newborn infants. We have several strengths that will advance the collaborative work of the NRN. 1. Our NICU is a world leader in the care of periviable infants, born at 22 and 23 weeks’ gestation. The survival rate of this population at the University of Iowa is the best in the United States, and the majority of these survivors are free of neurodevelopmental impairment. We bring expertise to inform research design as well as a relatively large periviable population available to participate in NRN studies. Our mortality for extremely low birth weight infants is perennially among the lowest in the NRN. 2. We have a strong tradition and culture of clinical research in infants. Our clinical research infrastructure in the NICU has a decades-long track record of successful participation in multicenter studies and contributions to important neonatal study findings. 3. Our NICU is the leading US center in the emerging neonatal subspecialty of neonatal hemodynamics. Our Hemodynamics group has developed the study methods and echocardiographic measurement standards for this modality and are global experts in its use both clinically and in physiologic and interventional research. That expertise can be harnessed in the NRN to pursue novel study designs. 4. As the only academic medical center in a largely rural state with an economy based in agriculture, we represent a population that is not otherwise well represented in the NICHD Network. Our partner site at Sanford Health in Sioux Falls, SD further enhances this diversity with the addition of a Native American population to our combined rural population. If the results of Network studies are to be generalized to patients throughout the country, this large area of the country should be represented. The University of Iowa Network center represents this region and population. 5. We have contributed significantly to the NRN’s work through the last 7 years. We have been among the highest enrolling sites in several studies despite our relatively low population, and we have had excellent follow-up rates for infants both in trials and in the Follow-up observational study.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $331,826 )
2025	2025	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	002	20	4/3/2025	NON-COMPETING CONTINUATION	$331,826
2025	2023	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	18	3/14/2025	COMPETING CONTINUATION	$1
2025	2022	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	17	3/14/2025	NON-COMPETING CONTINUATION	-$1
														Subtotal = $331,826

Issue Date FY: 2024 ( Subtotal = $338,534 )
2024	2024	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	19	6/6/2024	NON-COMPETING CONTINUATION	$33,854
2024	2024	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	19	4/10/2024	NON-COMPETING CONTINUATION	$304,680
														Subtotal = $338,534

Issue Date FY: 2023 ( Subtotal = $342,098 )
2023	2023	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	18	6/12/2023	COMPETING CONTINUATION	$0
2023	2023	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	18	3/30/2023	COMPETING CONTINUATION	$342,098
														Subtotal = $342,098

Issue Date FY: 2022 ( Subtotal = $264,235 )
2022	2022	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	17	5/12/2022	NON-COMPETING CONTINUATION	$26,425
2022	2022	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	17	3/31/2022	NON-COMPETING CONTINUATION	$237,810
														Subtotal = $264,235

Issue Date FY: 2021 ( Subtotal = $264,235 )
2021	2021	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	002	16	6/15/2021	NON-COMPETING CONTINUATION	$0
2021	2021	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	16	2/12/2021	NON-COMPETING CONTINUATION	$264,235
2021	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	15	2/8/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $264,235

Issue Date FY: 2020 ( Subtotal = $264,235 )
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	15	3/25/2020	NON-COMPETING CONTINUATION	$264,235
														Subtotal = $264,235

Issue Date FY: 2019 ( Subtotal = $270,166 )
2019	2019	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	14	3/21/2019	NON-COMPETING CONTINUATION	$270,166
														Subtotal = $270,166

Issue Date FY: 2018 ( Subtotal = $275,973 )
2018	2018	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	13	5/2/2018	NON-COMPETING CONTINUATION	$27,598
2018	2018	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	13	3/26/2018	NON-COMPETING CONTINUATION	$248,375
														Subtotal = $275,973

Issue Date FY: 2017 ( Subtotal = $281,573 )
2017	2017	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	12	3/30/2017	NON-COMPETING CONTINUATION	$253,415
2017	2017	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	12	6/20/2017	NON-COMPETING CONTINUATION	$28,158
														Subtotal = $281,573

Issue Date FY: 2016 ( Subtotal = $287,292 )
2016	2016	UNIVERSITY OF IOWA	2 GILMORE HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	11	3/22/2016	COMPETING CONTINUATION	$287,292
														Subtotal = $287,292

Grand Total All Awards = $2,920,167

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NICHD Cooperative Multicenter Neonatal Research Network

Award Number: UG1HD053109

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/05/2006

PERIOD OF PERFORMANCE END DATE: 03/31/2030

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