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Maternal Fetal Medicine Units Network - Northwestern Study Center

Award Number: UG1HD040512
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2001
PERIOD OF PERFORMANCE END DATE: 03/31/2030

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Maternal Fetal Medicine Units Network - Northwestern Study Center - PROJECT SUMMARY In the United States (US), there are nearly 4 million births per year, and childbirth is the leading indication for hospitalization. Correspondingly, the prevention of preterm birth and maternal morbidity are important clinical and public health goals. In addition, adverse maternal and neonatal outcomes are sources of major health inequities in the US; improvements in obstetric care, therapeutic interventions, and screening or diagnostic strategies have the potential to improve outcomes for all individuals, and particularly those from diverse populations. Innovative and transformational obstetric research is required to achieve these goals, making rigorous, multi-site clinical trials and observational studies designed to improve obstetric outcomes of the utmost importance. The Maternal-Fetal Medicine Units (MFMU) Network, by creating a multi-site research infrastructure, is an important mechanism to effectively accomplish this goal. The Northwestern Study Center, through its use of innovative recruitment and study designs, strong scientific leadership, outstanding academic productivity, and a large and diverse patient population available for research, has been a productive member of the MFMU Network since 2001. The Northwestern Study Center is composed of two institutions – Northwestern University and NorthShore University HealthSystem – that have a two-decade history of successful collaboration, including within the MFMU Network. The combined volume of birthing individuals receiving care at these sites is 19,000 births; a high volume of these births occur to individuals who are from diverse, underrepresented populations or at high risk for adverse outcomes. In this application, we propose that the Northwestern Study Center continues to participate in the NICHD MFMU Network. A team of experienced clinical researchers (Lynn Yee, MD, MPH; Michelle Kominiarek, MD, MS; Beth Plunkett, MD, MPH; Gail Mallett, RN), who have longstanding and nationally-recognized expertise with obstetric clinical research in general and the MFMU Network specifically, lead this renewal application. With strong institutional support, a uniquely collaborative research environment, and prior successful participation in and leadership of multi-site clinical trials, the Northwestern Study Center will continue its significant contributions to the MFMU Network’s goals through robust enrollment of socioeconomically diverse individuals and the completion of novel and important studies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $322,525 )
2025	2025	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	26	3/28/2025	NON-COMPETING CONTINUATION	$322,525
														Subtotal = $322,525

Issue Date FY: 2024 ( Subtotal = $322,525 )
2024	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	003	25	4/30/2024	NON-COMPETING CONTINUATION	$32,252
2024	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	002	25	3/22/2024	NON-COMPETING CONTINUATION	$290,273
2024	2024	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	004	25	8/12/2024	NON-COMPETING CONTINUATION	$0
2024	2023	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	001	24	3/5/2024	COMPETING CONTINUATION	$27,161
2024	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	23	3/5/2024	NON-COMPETING CONTINUATION	-$27,161
														Subtotal = $322,525

Issue Date FY: 2023 ( Subtotal = $337,525 )
2023	2023	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	001	24	3/31/2023	COMPETING CONTINUATION	$337,525
2023	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	23	3/8/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $337,525

Issue Date FY: 2022 ( Subtotal = $319,366 )
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	003	23	5/6/2022	NON-COMPETING CONTINUATION	$0
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	002	23	4/18/2022	NON-COMPETING CONTINUATION	$319,366
2022	2021	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	001	22	11/23/2021	COMPETING CONTINUATION	$6,933
2022	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	21	11/23/2021	NON-COMPETING CONTINUATION	-$6,933
														Subtotal = $319,366

Issue Date FY: 2021 ( Subtotal = $295,195 )
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	001	22	5/17/2021	COMPETING CONTINUATION	-$37,352
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	22	3/29/2021	COMPETING CONTINUATION	$332,547
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	002	22	8/31/2021	COMPETING CONTINUATION	$0
														Subtotal = $295,195

Issue Date FY: 2020 ( Subtotal = $264,762 )
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	001	21	9/23/2020	NON-COMPETING CONTINUATION	$0
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	21	3/18/2020	NON-COMPETING CONTINUATION	$264,762
														Subtotal = $264,762

Issue Date FY: 2019 ( Subtotal = $398,413 )
2019	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	20	3/27/2019	NON-COMPETING CONTINUATION	$266,321
2019	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	002	20	8/15/2019	SUPPLEMENT FOR EXPANSION	$132,092
2019	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	001	20	6/25/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $398,413

Issue Date FY: 2018 ( Subtotal = $267,962 )
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	001	19	5/1/2018	NON-COMPETING CONTINUATION	$26,797
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	19	3/10/2018	NON-COMPETING CONTINUATION	$241,165
														Subtotal = $267,962

Issue Date FY: 2017 ( Subtotal = $269,738 )
2017	2017	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	001	18	6/13/2017	NON-COMPETING CONTINUATION	$26,974
2017	2017	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	18	3/3/2017	NON-COMPETING CONTINUATION	$242,764
														Subtotal = $269,738

Issue Date FY: 2016 ( Subtotal = $285,010 )
2016	2016	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Child Health and Human Development Extramural Research	000	17	3/1/2016	COMPETING CONTINUATION	$285,010
														Subtotal = $285,010

Grand Total All Awards = $3,083,021

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Maternal Fetal Medicine Units Network - Northwestern Study Center

Award Number: UG1HD040512

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2001

PERIOD OF PERFORMANCE END DATE: 03/31/2030

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