Saturday, November 23, 2024 11/23/2024

Health Systems Node of the NIDA Clinical Trials Network

Award Number: UG1DA040314
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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ABSTRACT Substance use (SU) and substance use disorders (SUD) cause extensive morbidity and mortality but have been neglected historically by mainstream health care. The Health Systems Node joined the National Institute on Drug Abuse’s Clinical Trials Network (CTN) in 2015, led by Drs. Campbell, Weisner and Bradley, addiction research leaders in innovative implementation research and pragmatic trials in medical settings. Our node includes 16 Learning Health Systems with national representation and rich population diversity, and represents over 26 million patients. Our faculty are researchers who are embedded in their health systems and committed to cutting-edge addiction research. They bring multidisciplinary expertise in conducting research using innovative methods in different medical settings (e.g. primary care, addiction medicine, OB/GYN, psychiatry, rural communities), and with diverse populations (e.g. under-represented minorities, adolescents, pregnant women, patients with HIV). The node had an outstanding track record in its first 5 years leading 6 multi-site studies, including the CTN’s first entirely electronic health record (EHR)-based pragmatic implementation trial as well as participating in several studies led by other nodes. This renewal application builds upon that success to address the CTN’s objectives over the next 5 years through 3 broad Research Agendas: 1) To test approaches to increasing identification of SU and SUD, and engagement in treatment. For example, we propose a multisite implementation trial to test an innovative approach to implementing cannabis and other drug screening and assessment for SUD; 2) To test new approaches to improve SUD outcomes in medical settings. For example, we propose a point-of-care pragmatic effectiveness trial of telephonic nurse collaborative care and an efficacious smartphone-based SUD treatment, in patients with newly diagnosed SUD; and 3) To develop novel measures and methods for SUD research using EHRs. For example, we propose to validate a 7-item SU severity measure developed by the NIH Roadmap initiative Patient Reported Outcome Measurement Information System (PROMIS) for use in measurement-based care of SUD. These agendas emphasize population-based studies, including pragmatic randomized controlled trials, comparative effectiveness studies, and implementation research, and leverage EHRs. Public Health and Clinical Practice Impact. Over 14.9 million patients with untreated SUD have health care visits annually in the US. If 10% of these patients were identified, engaged and successfully treated, it would translate to 1.5 million patients with resolved SUD each year who otherwise would have gone untreated. The Health Systems Node faculty and infrastructure, in collaboration with the CTN, are uniquely positioned to conduct and disseminate research that advances the integration of SUD treatment into routine medical care, and ultimately to improve patient outcomes and public health.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,351,122 )
2024	2024	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	004	10	7/18/2024	NON-COMPETING CONTINUATION	$0
2024	2024	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	001	10	3/8/2024	NON-COMPETING CONTINUATION	$1,216,034
2024	2024	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	002	10	4/24/2024	NON-COMPETING CONTINUATION	$135,088
2024	2024	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	003	10	5/3/2024	NON-COMPETING CONTINUATION	$0
2024	2023	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	000	9	12/18/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,351,122

Issue Date FY: 2023 ( Subtotal = $839,126 )
2023	2023	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	000	9	2/27/2023	NON-COMPETING CONTINUATION	$839,126
2023	2023	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	005	9	6/9/2023	NON-COMPETING CONTINUATION	$0
2023	2023	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	004	9	4/7/2023	NON-COMPETING CONTINUATION	$0
2023	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	003	8	3/29/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	002	8	2/28/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	001	8	2/28/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $839,126

Issue Date FY: 2022 ( Subtotal = $2,899,797 )
2022	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	010	8	8/18/2022	SUPPLEMENT FOR EXPANSION	$226,130
2022	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	009	8	7/22/2022	NON-COMPETING CONTINUATION	$0
2022	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	014	8	9/21/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	015	8	9/23/2022	NON-COMPETING CONTINUATION	$0
2022	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	000	8	3/1/2022	NON-COMPETING CONTINUATION	$779,367
2022	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	011	8	8/19/2022	SUPPLEMENT FOR EXPANSION	$399,123
2022	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	013	8	8/23/2022	SUPPLEMENT FOR EXPANSION	$1,463,989
2022	2022	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	012	8	8/22/2022	SUPPLEMENT FOR EXPANSION	$34,184
2022	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	004	5	6/29/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	008	5	6/29/2022	NON-COMPETING CONTINUATION	-$2,996
2022	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	005	5	6/29/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2018	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	007	4	6/29/2022	NON-COMPETING CONTINUATION	$0
2022	2018	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	002	4	6/29/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2018	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	003	4	6/29/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2017	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	001	3	6/29/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2017	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Use and Addiction Research Programs	006	3	6/29/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,899,797

Issue Date FY: 2021 ( Subtotal = $1,064,242 )
2021	2021	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	011	7	5/6/2021	NON-COMPETING CONTINUATION	$75,985
2021	2021	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	010	7	4/30/2021	SUPPLEMENT FOR EXPANSION	$41,110
2021	2021	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	009	7	3/11/2021	NON-COMPETING CONTINUATION	$0
2021	2021	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	013	7	8/23/2021	NON-COMPETING CONTINUATION	$0
2021	2021	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	012	7	8/3/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2021	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	008	7	2/22/2021	NON-COMPETING CONTINUATION	$786,025
2021	2021	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	007	6	1/22/2021	SUPPLEMENT FOR EXPANSION	$161,122
2021	2020	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	006	6	12/3/2020	COMPETING CONTINUATION	$3,799,842
2021	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	004	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$384,120
2021	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	005	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$813,105
2021	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	000	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$651,851
2021	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	001	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$310,736
2021	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	003	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$1,223,031
2021	2019	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	002	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$416,999
														Subtotal = $1,064,242

Issue Date FY: 2020 ( Subtotal = $5,203,227 ) (Continued on the next page)
2020	2020	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	006	6	8/21/2020	SUPPLEMENT FOR EXPANSION	$123,552
2020	2020	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	005	6	8/10/2020	COMPETING CONTINUATION	$0
2020	2020	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	003	6	6/1/2020	SUPPLEMENT FOR EXPANSION	$305,437
2020	2020	KAISER FOUNDATION HOSPITALS	1800 HARRISON ST FL 16	OAKLAND	CA	94612	ALAMEDA	USA	Drug Abuse and Addiction Research Programs	002	6	5/29/2020	COMPETING CONTINUATION	$4,774,238
Grand Total All Awards = $32,505,749

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Health Systems Node of the NIDA Clinical Trials Network

Award Number: UG1DA040314

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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