Wednesday, March 22, 2023 3/22/2023

Northeast Node of the National Drug Abuse Clinical Trials Network

Award Number: UG1DA040309
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Project Summary/Abstract This proposal is a competing renewal application of the Northeast Node of the National Drug Abuse Treatment Clinical Trials Network (CTN), which joined the CTN in 2015. The Northeast Node brought hundreds of community and healthcare partners across the states of New Hampshire, Vermont, and Maine to the CTN community for the first time. These states have among the very highest rates of substance use in the U.S., including opioid use, and they include some of the most rural communities in the U.S. The Node has brought significant expertise to the CTN in conducting practical, rigorous, innovative, and highly impactful trials focused on improving the treatment of substance use disorders (SUDs) in community systems in the Northeast and in partnership with other CTN Nodes across the nation. Node Investigators have extensive experience in leading national and multi-national clinical trials, digital technology; medication and behavioral treatments for opioid use disorder; co-occurring SUDs and mental health disorders; SUD and chronic pain; SUD in pregnant women; opioid, cannabis, tobacco, alcohol, stimulant, and polydrug treatment; SUD prevention and treatment among youth; and implementation science. The Northeast Node is embedded within the Center for Technology and Behavioral Health (CTBH), a NIDA-funded P30 “Center of Excellence”. The Node thus brings significant expertise in developing, evaluating, and implementing digital treatments for SUDs, with a focus on overcoming the striking disparities in treatment access and treatment quality evident in healthcare across the globe. In the renewal period, the Node proposes to enhance its activities and contributions to the national CTN to embrace advances in scientific discovery and research innovations that offer great promise for increasing the reach and effectiveness of treatments for SUDs. The Node will engage a broader group of investigators that bring additional expertise in data science (bioinformatics, predictive modeling, artificial intelligence, social media, data privacy/security) and experimental design (micro-randomized trials, adaptive designs, and implementation/systems science). With this expanded group of partners, it will support and grow a productive research agenda in the CTN with a focus on (a) digital health and data analytics, including research focused on providing personalized, science-based resources to individuals with SUD via digital technology and (b) expanding low threshold access to science-based SUD care, particularly in rural contexts (e.g., general medical settings; pharmacies; and community organizations). And the Node will lead an expansion of CTN research on the (c) rapidly evolving landscape of cannabis use as well as (d) co-morbid SUD and mental health disorders. The Node will establish Community and Policy Advisory Boards to complement the existing communication infrastructure between Node investigators and their partners, with a focus on identifying the most significant and timely SUD needs in our communities and scaling-up and sustaining best practices.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $1,854,476 )
2023	2023	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	001	9	2/22/2023	NON-COMPETING CONTINUATION	$1,854,476
2023	2022	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	8	1/13/2023	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2022 ( Subtotal = $2,282,711 )
2022	2022	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	003	8	4/7/2022	NON-COMPETING CONTINUATION	$1,228,351
2022	2022	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	001	8	3/1/2022	NON-COMPETING CONTINUATION	$799,600
2022	2022	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	002	8	4/6/2022	SUPPLEMENT FOR EXPANSION	$254,760
2022	2021	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	7	10/15/2021	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2021 ( Subtotal = $2,213,818 )
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	007	7	5/5/2021	NON-COMPETING CONTINUATION	$1,051,418
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	006	7	3/15/2021	NON-COMPETING CONTINUATION	$806,202
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	008	6	5/6/2021	SUPPLEMENT FOR EXPANSION	$106,265
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	009	7	5/25/2021	SUPPLEMENT FOR EXPANSION	$249,933
2021	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	004	6	1/6/2021	COMPETING CONTINUATION	$0
2021	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	005	6	2/25/2021	COMPETING CONTINUATION	$0
2021	2020	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	003	6	12/3/2020	COMPETING CONTINUATION	$1,944,837
2021	2019	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$1,221,589
2021	2019	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	002	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$17,058
2021	2019	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	001	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$706,190


Issue Date FY: 2020 ( Subtotal = $1,644,875 )
2020	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	002	6	6/2/2020	SUPPLEMENT FOR EXPANSION	$622,500
2020	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	001	6	6/1/2020	COMPETING CONTINUATION	$1,022,375
2020	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	5	12/18/2019	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2019 ( Subtotal = $4,913,242 )
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	004	5	5/9/2019	SUPPLEMENT FOR EXPANSION	$339,426
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	009	5	6/26/2019	SUPPLEMENT FOR EXPANSION	$1,221,589
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	007	5	6/24/2019	SUPPLEMENT FOR EXPANSION	$951,169
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	008	5	6/25/2019	SUPPLEMENT FOR EXPANSION	$706,190
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	002	4	4/11/2019	SUPPLEMENT FOR EXPANSION	$362,193
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	001	5	4/4/2019	NON-COMPETING CONTINUATION	$748,377
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	005	5	5/13/2019	SUPPLEMENT FOR EXPANSION	$374,715
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	006	4	6/21/2019	SUPPLEMENT FOR EXPANSION	$3,603
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	003	4	4/22/2019	SUPPLEMENT FOR EXPANSION	$205,980
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	010	5	7/22/2019	NON-COMPETING CONTINUATION	$0
2019	2018	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	4	11/1/2018	NON-COMPETING CONTINUATION	$0


Issue Date FY: 2018 ( Subtotal = $1,468,852 )
2018	2018	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	001	4	6/19/2018	SUPPLEMENT FOR EXPANSION	$315,967
2018	2018	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	4	5/3/2018	NON-COMPETING CONTINUATION	$748,377
2018	2018	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	002	4	7/16/2018	SUPPLEMENT FOR EXPANSION	$404,508


Issue Date FY: 2017 ( Subtotal = $1,296,541 )
2017	2017	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	001	3	7/14/2017	SUPPLEMENT FOR EXPANSION	$290,375
2017	2017	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	3	5/31/2017	NON-COMPETING CONTINUATION	$748,377
2017	2017	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	002	3	7/20/2017	SUPPLEMENT FOR EXPANSION	$257,789


Issue Date FY: 2016 ( Subtotal = $1,020,622 )
2016	2016	DARTMOUTH COLLEGE	11 ROPE FERRY ROAD, #6210	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	001	2	7/26/2016	SUPPLEMENT FOR EXPANSION	$272,245
2016	2016	DARTMOUTH COLLEGE	11 ROPE FERRY ROAD, #6210	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	2	5/17/2016	NON-COMPETING CONTINUATION	$748,377


Issue Date FY: 2015 ( Subtotal = $758,097 )
2015	2015	DARTMOUTH COLLEGE	11 ROPE FERRY ROAD, #6210	HANOVER	NH	03755	GRAFTON	USA	Drug Abuse and Addiction Research Programs	000	1	7/17/2015	NEW	$758,097


Grand Total All Awards = $17,453,234

Sum of Action Amount is $17,453,234;

Grand Total = $17,453,234

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Northeast Node of the National Drug Abuse Clinical Trials Network

Award Number: UG1DA040309

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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