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Northeast Node of the National Drug Abuse Treatment Clinical Trials Network

Award Number: UG1DA040309
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Northeast Node of the National Drug Abuse Treatment Clinical Trials Network - Project Summary/Abstract This proposal is a competing renewal application of the Northeast Node of the National Drug Abuse Treatment Clinical Trials Network (CTN), which has been part of the CTN since 2015. The Northeast Node has engaged a network of hundreds of community, healthcare, researcher, policy, and payor partners across the states of New Hampshire, Vermont, and Maine. These states have among the very highest rates of substance use and overdose mortality in the U.S. and include some of the most rural communities in the U.S. The Node has brought significant expertise to the CTN in successfully leading multi-site clinical trials as well as feasibility, efficacy, effectiveness, implementation, and hybrid implementation/effectiveness research studies focused on improving the prevention and treatment of substance use disorders (SUDs) and reducing harms of SUDs; community- and culturally-informed research; digital health, Artificial Intelligence, data science, data analytics, machine/deep learning, digital phenotyping and digital therapeutics for SUDs and related issues; and collaborating with health systems, research networks, community organizations and our SUD policymakers, state authorities and congressional delegates. The Node has also been a leader in many national CTN-wide initiatives, including launching and leading the first-of-its kind national Community Representative Council (CIRCL) to inform the work of the CTN across the nation and leading the strategic planning of the CTN, with PI Marsch serving as Chair of the national CTN Steering Committee. This renewal application builds on the Node’s strong infrastructure, track record of innovation and impact, and expertise of direct relevance to the priorities in RFA-DA-25-027 for the next iteration of the CTN. Since the Northeast Node’s inception 9 years ago, the Node has led or partnered on 17 CTN studies, 6 of which will continue into the renewal phase. And we plan to expand our research contributions to the CTN to promote advances in scientific discovery that offer great promise for increasing the reach and effectiveness of treatments for SUDs that address both key and emerging substance use needs. A key focus will be on engaging and impacting underserved populations, including rural and socioeconomically disadvantaged communities and other health disparity populations. We seek to generate evidence to inform healthcare policy and payor decisions and scale-up and sustain best practices. We will also enhance our infrastructure and processes to best ensure our broad community informs the priorities for the research and dissemination agenda of our Node as well as the national CTN by formalizing a Northeast Node Partner Exchange and increasing the deliverables of CIRCL to enhance its reach and impact. And we will enhance our infrastructure and processes to expand our training program to provide trainees in our Node the opportunity to gain valuable hands-on experience in designing, participating in, and managing clinical studies in the CTN.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $742,151 )
2025	2025	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	000	11	1/17/2025	COMPETING CONTINUATION	$742,151
2025	2025	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	001	11	3/5/2025	COMPETING CONTINUATION	$0
														Subtotal = $742,151

Issue Date FY: 2024 ( Subtotal = $1,738,506 )
2024	2024	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	004	10	9/12/2024	NON-COMPETING CONTINUATION	$0
2024	2024	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	003	10	7/18/2024	NON-COMPETING CONTINUATION	$0
2024	2024	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	001	10	3/7/2024	NON-COMPETING CONTINUATION	$1,564,656
2024	2024	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	002	10	4/30/2024	NON-COMPETING CONTINUATION	$173,850
2024	2023	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	000	9	12/6/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,738,506

Issue Date FY: 2023 ( Subtotal = $2,855,069 )
2023	2023	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	002	9	9/15/2023	SUPPLEMENT FOR EXPANSION	$1,000,593
2023	2023	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	001	9	2/22/2023	NON-COMPETING CONTINUATION	$1,854,476
2023	2022	TRUSTEES OF DARTMOUTH COLLEGE	7 LEBANON ST	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	000	8	1/13/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,855,069

Issue Date FY: 2022 ( Subtotal = $2,282,711 )
2022	2022	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	002	8	4/6/2022	SUPPLEMENT FOR EXPANSION	$254,760
2022	2022	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	003	8	4/7/2022	NON-COMPETING CONTINUATION	$1,228,351
2022	2022	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	001	8	3/1/2022	NON-COMPETING CONTINUATION	$799,600
2022	2021	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	000	7	10/15/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,282,711

Issue Date FY: 2021 ( Subtotal = $2,213,818 )
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	007	7	5/5/2021	NON-COMPETING CONTINUATION	$1,051,418
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	006	7	3/15/2021	NON-COMPETING CONTINUATION	$806,202
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	009	7	5/25/2021	SUPPLEMENT FOR EXPANSION	$249,933
2021	2021	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	008	6	5/6/2021	SUPPLEMENT FOR EXPANSION	$106,265
2021	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	005	6	2/25/2021	COMPETING CONTINUATION	$0
2021	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	004	6	1/6/2021	COMPETING CONTINUATION	$0
2021	2020	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	003	6	12/3/2020	COMPETING CONTINUATION	$1,944,837
2021	2019	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	002	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$17,058
2021	2019	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	001	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$706,190
2021	2019	TRUSTEES OF DARTMOUTH COLLEGE	6001 PARKHURST HALL STE 207	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	000	5	12/3/2020	SUPPLEMENT FOR EXPANSION	-$1,221,589
														Subtotal = $2,213,818

Issue Date FY: 2020 ( Subtotal = $1,644,875 )
2020	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	001	6	6/1/2020	COMPETING CONTINUATION	$1,022,375
2020	2020	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	002	6	6/2/2020	SUPPLEMENT FOR EXPANSION	$622,500
2020	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	000	5	12/18/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,644,875

Issue Date FY: 2019 ( Subtotal = $4,913,242 )
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	006	4	6/21/2019	SUPPLEMENT FOR EXPANSION	$3,603
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	010	5	7/22/2019	NON-COMPETING CONTINUATION	$0
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	004	5	5/9/2019	SUPPLEMENT FOR EXPANSION	$339,426
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	007	5	6/24/2019	SUPPLEMENT FOR EXPANSION	$951,169
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	005	5	5/13/2019	SUPPLEMENT FOR EXPANSION	$374,715
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	001	5	4/4/2019	NON-COMPETING CONTINUATION	$748,377
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	009	5	6/26/2019	SUPPLEMENT FOR EXPANSION	$1,221,589
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	008	5	6/25/2019	SUPPLEMENT FOR EXPANSION	$706,190
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	003	4	4/22/2019	SUPPLEMENT FOR EXPANSION	$205,980
2019	2019	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	002	4	4/11/2019	SUPPLEMENT FOR EXPANSION	$362,193
2019	2018	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	000	4	11/1/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $4,913,242

Issue Date FY: 2018 ( Subtotal = $1,468,852 )
2018	2018	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	001	4	6/19/2018	SUPPLEMENT FOR EXPANSION	$315,967
2018	2018	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	002	4	7/16/2018	SUPPLEMENT FOR EXPANSION	$404,508
2018	2018	TRUSTEES OF DARTMOUTH COLLEGE	1 HINMAN DARTMOUTH COLLEGE	HANOVER	NH	03755	GRAFTON	USA	Drug Use and Addiction Research Programs	000	4	5/3/2018	NON-COMPETING CONTINUATION	$748,377
														Subtotal = $1,468,852

Issue Date FY: 2017 ( Subtotal = $1,296,541 ) (Continued on the next page)
Grand Total All Awards = $20,934,484

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Northeast Node of the National Drug Abuse Treatment Clinical Trials Network

Award Number: UG1DA040309

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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