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Improving awareness of women with hypertension: ROAR (Rural, Obese, At Risk)

Award Number: U54HL169191
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2023
PERIOD OF PERFORMANCE END DATE: 08/31/2028

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Improving awareness of women with hypertension: ROAR (Rural, Obese, At Risk) - More than 1 in 3 women are living with heart disease and many are unaware of the risks. Hypertension is a major modifiable risk factor for cardiovascular disease (CVD), and ~47% of adults in the US have hypertension. In ~85% of cases, the cause of hypertension is unknown and only ~50% of patients taking medication achieve blood pressure (BP) control to recommended levels. A critical barrier to limiting premature death from CVD is lack of awareness surrounding the risks of CVD. Our location in the Southeast of the US will contribute to our impact. The prevalence of hypertension and obesity are high in GA, MS, and SC. The prevalence of hypertension and associated risk varies across populations. Indeed, the prevalence of hypertension in Black people in the US is among the highest in the world. Our overall goal is to transform academic and community understanding of sex as a biological variable (SABV) in the consideration of hypertension. We will accomplish this through the creation and dissemination of innovative educational content, the development of strategic partnerships, and enhanced community engagement in the Southeast of the US. This SCORE is designed to provide novel insight into the mechanisms controlling BP in females and males, develop a comprehensive educational platform on SABV in CVD extending from grade school to medical school, and increase awareness and education of CVD and the risks of uncontrolled hypertension in women across the health span through community outreach. This SCORE has 4 objectives. Objective 1 is to conduct cutting edge research to advance our understanding of mechanisms that control BP in males and females to limit cardiovascular risk. Objective 2 is to develop a strong research pipeline of biomedical scientists trained in the field of SABV in CVD. Objective 3 is to establish a community outreach pipeline of trained scientists to increase awareness of SABV and promote optimal cardiovascular healthcare for men and women. Objective 4 is to empower the community to self-monitor and work to identify barriers to improving access to healthcare. The outcomes of our proposed SCORE include not only advances in science and training of the next generation of leaders in the study of the impact of biological sex on the development and progression of CVD, but also the development of a range of educational content that will be fully available to the Consortium. This will include 1) the development educational materials by medical illustrators for students/trainees at all stages, the community, and physicians, 2) establishing a SABV Mentoring Academy, 3) creating a SABV curriculum and workshop for students, fellows, and junior investigators. The impact of our work will be to increase recognition and awareness of the risks of CVD and hypertension to women across their health span and best practices for SAVB experimental design. Our comprehensive community outreach plan will also be critical to reach a highly at-risk population in the Southeast of the US to increase routine cardiovascular health monitoring and decrease the overall CVD burden on both the population and the healthcare system.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $1,460,600 )
2026	2026	AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC	AUGUSTA UNIVERSITY 1120 15TH STREET	AUGUSTA	GA	30912	RICHMOND	USA	Cardiovascular Diseases Research	001	4	8/19/2026	NON-COMPETING CONTINUATION	$1,460,600
2026	2025	AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC	AUGUSTA UNIVERSITY 1120 15TH STREET	AUGUSTA	GA	30912	RICHMOND	USA	Cardiovascular Diseases Research	000	3	5/5/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,460,600

Issue Date FY: 2025 ( Subtotal = $1,493,938 )
2025	2025	AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC	AUGUSTA UNIVERSITY 1120 15TH STREET	AUGUSTA	GA	30912	RICHMOND	USA	Cardiovascular Diseases Research	001	3	9/2/2025	NON-COMPETING CONTINUATION	$1,493,938
2025	2024	AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC	AUGUSTA UNIVERSITY 1120 15TH STREET	AUGUSTA	GA	30912	RICHMOND	USA	Cardiovascular Diseases Research	000	2	7/18/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,493,938

Issue Date FY: 2024 ( Subtotal = $1,469,903 )
2024	2024	AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC	AUGUSTA UNIVERSITY 1120 15TH STREET	AUGUSTA	GA	30912	RICHMOND	USA	Cardiovascular Diseases Research	001	2	8/30/2024	NON-COMPETING CONTINUATION	$1,469,903
2024	2023	AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC	AUGUSTA UNIVERSITY 1120 15TH STREET	AUGUSTA	GA	30912	RICHMOND	USA	Cardiovascular Diseases Research	000	1	8/26/2024	NEW	$0
														Subtotal = $1,469,903

Issue Date FY: 2023 ( Subtotal = $1,505,913 )
2023	2023	AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.	1120 15TH ST STE CJ3301	AUGUSTA	GA	30912	RICHMOND	USA	Cardiovascular Diseases Research	000	1	9/1/2023	NEW	$1,505,913
														Subtotal = $1,505,913

Grand Total All Awards = $5,930,354

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Improving awareness of women with hypertension: ROAR (Rural, Obese, At Risk)

Award Number: U54HL169191

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2023

PERIOD OF PERFORMANCE END DATE: 08/31/2028

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