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American Heart Association Tobacco Center for Regulatory Science (A-TRAC) 2.0

Award Number: U54HL120163
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/19/2013
PERIOD OF PERFORMANCE END DATE: 08/31/2025

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American Heart Association Tobacco Center for Regulatory Science (A-TRAC) 2.0 - PROJECT SUMMARY The overall goal of the American Heart Association (AHA) Tobacco Regulation Center (ATRAC) is to provide scientific data relevant to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP). The integrative theme of the Center is to evaluate and communicate the cardiovascular effects of tobacco products, within the scientific domains of Health Effects, Toxicity and Communications. Research within the Center will contribute to the scientific base of tobacco regulatory science by evaluating the cardiovascular effects of tobacco products and their constituents. The Center will support a multi-disciplinary research program to assess the toxicity of tobacco products and their constituents in in vitro assays and animal models (Project 1); evaluate short- and long-term cardiovascular health effects of tobacco products (Project 2) and assess the cardiovascular disease risk associated with the use of non-cigarette tobacco products in multiple large NIH-supported cardiovascular cohorts (Project 3). To communicate the knowledge generated within the Center and other Tobacco Centers of Regulatory Science (TCORS), the Center will develop and test approaches for effective communication of the cardiovascular consequences of tobacco product use (Project 4). To facilitate uniformity, and quality control, all measurements will be conducted in a centralized Bioanalytical and Biomarker Core. The research activities within the Center will be coordinated by an Administrative Core, while the Career Enhancement Core will oversee the career development of new and early stage investigators. The Administrative Core will maintain close communication with federal partners and will oversee the development, funding and progress of Rapid Response Projects. Research supported by the Center will develop new understanding of the cardiovascular effects of current, new and emerging tobacco products; aid in the development of messages for communicating the cardiovascular risk associated with the use of tobacco products; and build and deploy capacity and expertise to respond to new developments. Collectively, Center research will broaden the scientific base of tobacco regulatory science to inform FDA's regulation of tobacco manufacturing, distribution and marketing.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2022	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	10	1/25/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2022	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	001	10	7/31/2024	NON-COMPETING CONTINUATION	$0
2024	2022	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	10	1/11/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	10	8/22/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $3,692,125 )
2022	2022	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	001	10	8/24/2022	NON-COMPETING CONTINUATION	$3,692,125
2022	2021	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	9	6/1/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,692,125

Issue Date FY: 2021 ( Subtotal = $3,692,125 )
2021	2021	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	001	9	8/30/2021	NON-COMPETING CONTINUATION	$52,000
2021	2021	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	9	8/24/2021	NON-COMPETING CONTINUATION	$3,640,125
														Subtotal = $3,692,125

Issue Date FY: 2020 ( Subtotal = $4,379,123 )
2020	2020	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Lung Diseases Research	001	8	8/31/2020	SUPPLEMENT FOR EXPANSION	$686,998
2020	2020	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	8	8/24/2020	NON-COMPETING CONTINUATION	$3,692,125
														Subtotal = $4,379,123

Issue Date FY: 2019 ( Subtotal = $4,034,644 )
2019	2019	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	004	7	9/12/2019	NON-COMPETING CONTINUATION	$3,640,125
2019	2018	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	003	6	5/10/2019	COMPETING CONTINUATION	$0
2019	2018	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	6	11/6/2018	COMPETING CONTINUATION	$0
2019	2018	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	002	6	5/1/2019	COMPETING CONTINUATION	$394,519
2019	2018	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	001	6	12/20/2018	COMPETING CONTINUATION	$0
														Subtotal = $4,034,644

Issue Date FY: 2018 ( Subtotal = $3,423,808 )
2018	2018	AMERICAN HEART ASSOCIATION, INC.	7272 GREENVILLE AVE	DALLAS	TX	75231	DALLAS	USA	Cardiovascular Diseases Research	000	6	8/31/2018	COMPETING CONTINUATION	$3,423,808
														Subtotal = $3,423,808

Grand Total All Awards = $19,221,825

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American Heart Association Tobacco Center for Regulatory Science (A-TRAC) 2.0

Award Number: U54HL120163

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/19/2013

PERIOD OF PERFORMANCE END DATE: 08/31/2025

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