Wednesday, April 24, 2024 4/24/2024

The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern University (C-THAN)

Award Number: U54EB027049
ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

View Award Abstract

The “C-THAN POCTRN COVID-19 Proposal” is a supplement to the existing Center for Innovation in Point-of- Care Technologies for HIV/AIDS at Northwestern (C-THAN) which aims to support development of technologies which can help address the urgent healthcare needs created by the COVID-19 pandemic. The extent and urgency of the situation requires an aggressive and innovative approach to accelerate the delivery of solutions to address immediate and future needs. Our approach augments the strong technical and clinical expertise within our own and the existing four POCTRN centers and their Coordinating Center. The specific aims are: 1) develop a SARS-CoV-2 ten-minute molecular diagnostic test based on the Minute Molecular Platform; and 2) scale up C-THAN’s established international network for COVID-19 technological development and testing of relevant products and assays in sub-Saharan Africa and other low- and middle- income countries (LMICs). For aim 1, C-THAN proposes the development of a ten-minute SARS-CoV-2 test for the Minute Molecular DASH (Diagnosis Analyzer for Selective Hybridization), a sample-to-answer platform for point-of-care use in medical clinics, emergency departments and urgent care centers. The DASH platform exploits novel fast PCR and microfluidic fabrication technologies developed at the Center for Innovation in Global Health Technologies (CIGHT) at Northwestern University. DASH technology can be adapted for high throughput uses such as airports, hospitals, nursing homes, emergency departments and drive-through testing sites. For aim 2, we will scale up C-THAN resources to expand addressing the impact of the pandemic. The C-THAN network consists of four biomedical engineering (BME) technology development sites plus three clinical validation/needs assessment sites. The BME sites include University of Cape Town and Stellenbosch University in South Africa, and University of Lagos and University of Ibadan in Nigeria. The seven clinical validation/needs assessment sites include ones located with the engineering sites plus at University of Jos in Nigeria, University of Bamako in Mali and Muhimbili University in Tanzania. The relationship of these sites with Northwestern University go back up to 22 years. We will utilize Northwestern’s Institute for Global Health Catalyzer Award Program which has been funding promising research projects addressing critical global health needs for over 10 years. Two weeks ago, the Institute redirected all proposals to address only COVID-19 activities. Basic scientists, biomedical engineers, infectious diseases specialists, virologist, pharmacologists and public health faculty are encouraged to apply for Catalyzer awards which are in the range of $25,000 for a one-year project. With this POCTRN supplement, we will “plus-up” these awards to a maximum of $100,000 each to increase the scope and pace of the development. Applications are being accepted on a rolling basis, and funding decisions are made within 7 days. These two approaches will rapidly accelerate the development of promising COVID-19 technologies both in the US and globally.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $1,754,217 )
2023	2023	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	6	9/15/2023	COMPETING CONTINUATION	$1,754,217
2023	2023	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	003	6	9/18/2023	COMPETING CONTINUATION	$0
2023	2022	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	9/7/2023	NON-COMPETING CONTINUATION	$0
2023	2022	NORTHWESTERN UNIVERSITY	633 CLARK STREET	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	5	9/8/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,754,217

Issue Date FY: 2022 ( Subtotal = $2,632,090 )
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	5	9/16/2022	SUPPLEMENT FOR EXPANSION	$1,184,948
2022	2022	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	5	8/9/2022	NON-COMPETING CONTINUATION	$1,447,142
2022	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	8/12/2022	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $2,632,090

Issue Date FY: 2021 ( Subtotal = $1,536,895 )
2021	2021	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	004	4	6/29/2021	NON-COMPETING CONTINUATION	$1,536,895
2021	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	003	2	5/28/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	1/29/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	11/10/2020	SUPPLEMENT FOR EXPANSION	$0
2021	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	3	5/14/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,536,895

Issue Date FY: 2020 ( Subtotal = $8,227,340 )
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	003	2	7/30/2020	SUPPLEMENT FOR EXPANSION	$0
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	002	3	5/29/2020	NON-COMPETING CONTINUATION	$1,519,571
2020	2020	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	5/22/2020	SUPPLEMENT FOR EXPANSION	$6,707,769
2020	2019	NORTHWESTERN UNIVERSITY	633 CLARK	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	2	12/6/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $8,227,340

Issue Date FY: 2019 ( Subtotal = $1,506,528 )
2019	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST EVANSTON	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	2	7/5/2019	NON-COMPETING CONTINUATION	$1,506,528
2019	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST EVANSTON	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	5/2/2019	NEW	$0
														Subtotal = $1,506,528

Issue Date FY: 2018 ( Subtotal = $1,515,803 )
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST EVANSTON	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	000	1	9/11/2018	NEW	$1,515,803
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST EVANSTON	EVANSTON	IL	60208	COOK	USA	Discovery and Applied Research for Technological Innovations to Improve Human Health	001	1	9/12/2018	NEW	$0
														Subtotal = $1,515,803

Grand Total All Awards = $17,172,873

Top

All Categories

About

Search

Reports

Data Submission

Award Information

The Center for Innovation in Point-of-Care Technologies for HIV/AIDS and Emerging Infectious Diseases at Northwestern University (C-THAN)

Award Number: U54EB027049

ORGANIZATION: NATIONAL INSTITUTE Of BIOMEDICAL IMAGING & BIOENGINEERING

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer