Thursday, July 3, 2025 7/3/2025

H3Africa Kidney Disease Research Network- Collaborative Centers

Award Number: U54DK116913
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2012
PERIOD OF PERFORMANCE END DATE: 08/31/2023

Group Awards By:

View Award Description

H3Africa Kidney Disease Research Network- Collaborative Centers - Chronic kidney disease (CKD) including end stage renal disease (CKD stage 5) is a major health problem in sub-Saharan Africa (SSA) affecting more than 50 million individuals but there is lamentable lack of research data and there is no promise of urgently needed preventative strategies. The lack of data on CKD in SSA are in part due to the absence of population-based epidemiologic studies of CKD and a scarcity of physician scientists conducting genetic, clinical and translational research on CKD according to local priorities. Herein, we propose to leverage the H3Africa Kidney Disease Research Network (H3A-KDRN) to (i) conduct genomics, clinical and translational research on the most prevalent forms of CKD; (ii) expand and support a well-trained cadre of African researchers and physician scientists to conduct CKD research according to regional priorities; (iii) engage SSA communities and research participants in the initiation, governance, implementation and dissemination of CKD research and (iv) foster collaboration with U.S.-based basic, clinical and translational researchers (including Africans in the diaspora) to elucidate etiologies and mechanisms and discover effective therapeutic and preventative strategies to combat the extraordinary burden of CKD in people of African ancestry globally The H3A-KDRN is organized as a research consortium initially composed of: (a) 15 academic medical centers/university teaching hospitals in five African countries- Cameroon - 1, Ghana – 4, Nigeria – 8, South Africa - 1 and Tanzania – 1; (b) 9 North American/Israeli research intensive academic medical institutions; (c) 3 shared cores – Training and Career Development, Data Management and Biostatistics and Genotyping Laboratories. At the end of the five-year funding requested in this application, The H3AKDRN will have accomplished the following: 1. Completion of three research projects on: (i) CKD in HIV-infected patients; and (ii) childhood and adolescent onset nephrotic syndrome and (iii) sickle cell disease nephropathy. These three prospective cohort studies will have a total sample size of 5800 participants. 2. Completion of training of four African-based research scientists toward PhD (n=2) and MSc (n=1) in Clinical and Translational Science (CTS) awarded by the University of Arizona 3. Completion of certificate training in clinical research methods for 45 African-based research personnel 4. Establish a high functioning regional Clinical and Translational Research Coordinating Center to support multicenter research in CKD and other non-communicable chronic diseases in SSA. With these foundational objectives, the H3Africa Kidney Disease Research Network will a transformative impact on CKD research in SSA and thence move us closer to the goal of reducing the burden of CKD in the 352 million Africans living in the five H3A-KDRN countries and in the 1.2 billion people of African descent globally.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2021	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	000	11	3/26/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2021	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	000	11	1/18/2022	NON-COMPETING CONTINUATION	$0
2022	2021	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	001	11	3/17/2022	NON-COMPETING CONTINUATION	$0
2022	2021	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	002	11	8/11/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $1,011,450 )
2021	2021	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	11	8/25/2021	SUPPLEMENT FOR EXPANSION	$229,856
2021	2021	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	001	11	8/24/2021	NON-COMPETING CONTINUATION	$781,594
2021	2020	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	000	10	1/8/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,011,450

Issue Date FY: 2020 ( Subtotal = $781,594 )
2020	2020	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	005	10	9/11/2020	NON-COMPETING CONTINUATION	$781,594
2020	2019	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	000	9	12/3/2019	NON-COMPETING CONTINUATION	$0
2020	2019	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	001	9	1/29/2020	NON-COMPETING CONTINUATION	$0
2020	2019	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	003	9	5/14/2020	NON-COMPETING CONTINUATION	$0
2020	2019	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	002	9	3/4/2020	NON-COMPETING CONTINUATION	$0
2020	2019	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Trans-NIH Research Support	004	9	7/9/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $781,594

Issue Date FY: 2019 ( Subtotal = $754,068 )
2019	2019	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	9	8/16/2019	NON-COMPETING CONTINUATION	$754,068
2019	2018	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	8	6/27/2019	NON-COMPETING CONTINUATION	$0
2019	2018	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	8	8/15/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $754,068

Issue Date FY: 2018 ( Subtotal = $781,594 )
2018	2018	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	004	8	9/24/2018	NON-COMPETING CONTINUATION	$781,594
2018	2017	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	003	7	9/22/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$781,594
2018	2017	COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA	CHARLES EASMON BUILDING	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	6	9/21/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$781,594
2018	2017	UNIVERSITY OF GHANA MEDICAL S CHOOL	KORLE BU	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	6	1/12/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$781,594
2018	2017	UNIVERSITY OF GHANA MEDICAL S CHOOL	KORLE BU	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	6	2/5/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$781,594
														Subtotal = $781,594

Issue Date FY: 2017 ( Subtotal = $781,594 )
2017	2017	UNIVERSITY OF GHANA MEDICAL S CHOOL	KORLE BU	ACCRA				GHA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	6	9/14/2017	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$781,594
														Subtotal = $781,594

Grand Total All Awards = $4,110,300

Top

All Categories

About

Search

Reports

Data Submission

Award Information

H3Africa Kidney Disease Research Network- Collaborative Centers

Award Number: U54DK116913

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2012

PERIOD OF PERFORMANCE END DATE: 08/31/2023

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer