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Appalachian Tobacco Regulatory Science Team (AppalTRuST)

Award Number: U54DA058256
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2023
PERIOD OF PERFORMANCE END DATE: 08/31/2028

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Appalachian Tobacco Regulatory Science Team (AppalTRuST) - Our overall goal, reflecting AppalTRUST’s Integrative Theme of investigating the effects of regulatory changes on tobacco product use in Appalachian KY, is to assess the impact of proposed tobacco product regulations using behavioral economic methods that we have developed and refined in past years to characterize the consumption of tobacco products within the complex nicotine marketplace of Appalachian KY, a rural region that would greatly benefit from focused tobacco regulatory science research. This project primarily falls under the Regulatory Scientific Domain of Impact Analysis. In 2009, the US Food and Drug Administration (FDA) was granted authority to regulate tobacco products to benefit public health. In the years since, the FDA has proposed potential regulatory actions that may benefit public health, including regulating the maximum nicotine content in combustible cigarettes and restricting flavors of combusted and noncombusted tobacco products. Estimating the impact of any proposed regulatory action is complicated by the existence of a complex tobacco marketplace containing multiple products that are economic substitutes for one another and the frequent introduction of new tobacco products by manufacturers. Furthermore, when compared to more urban, non-Appalachian communities, rural Appalachian communities often have 1) higher rates of tobacco product use overall, 2) different use patterns that include more combusted tobacco products, and 3) different product availability in tobacco stores. It is therefore important to estimate any differential impact of proposed tobacco-product regulations in Appalachia. Using an Experimental Tobacco Marketplace (ETM) model where product availability is manipulated across groups and demand elasticity and substitution is measured across tobacco products, we will estimate the impact of regulating 1) nicotine content of combusted cigarettes, 2) menthol flavor restrictions in combustible cigarettes, and 3) flavor additive restrictions in noncombusted nicotine/tobacco products including ENDS. Across two aims, we will assess the impact of these three regulations within Appalachia (Aim 1) and the effect of rurality on impact of these proposed regulations in Appalachia (Aim 2).


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $3,843,883 )
2025	2025	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	003	3	8/8/2025	NON-COMPETING CONTINUATION	$3,843,883
2025	2024	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	2	11/26/2024	NON-COMPETING CONTINUATION	$0
2025	2024	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	001	2	1/15/2025	NON-COMPETING CONTINUATION	$0
2025	2024	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	002	2	3/21/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $3,843,883

Issue Date FY: 2024 ( Subtotal = $3,866,213 )
2024	2024	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	2	8/7/2024	NON-COMPETING CONTINUATION	$3,866,213
														Subtotal = $3,866,213

Issue Date FY: 2023 ( Subtotal = $3,923,160 )
2023	2023	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION, THE	500 S LIMESTONE	LEXINGTON	KY	40526	FAYETTE	USA	Family Smoking Prevention and Tobacco Control Act Regulatory Research	000	1	9/25/2023	NEW	$3,923,160
														Subtotal = $3,923,160

Grand Total All Awards = $11,633,256

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Appalachian Tobacco Regulatory Science Team (AppalTRuST)

Award Number: U54DA058256

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2023

PERIOD OF PERFORMANCE END DATE: 08/31/2028

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