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3/3 Florida-California Cancer Research, Education and Engagement (CaRE2) Health Equity Center

Award Number: U54CA233465
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/20/2018
PERIOD OF PERFORMANCE END DATE: 08/31/2028

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3/3 Florida-California Cancer Research, Education and Engagement (CaRE2) Health Equity Center - SUMMARY – OVERALL COMPONENT The Florida-California Cancer Research, Education & Engagement (CaRE2) Health Equity is proposed by the University of Florida (UF), Florida A&M University (FAMU) and the University of Southern California-Norris Comprehensive Cancer Center (USC-NCCC) to eliminate cancer health disparities in Florida, California and nationally. The long term goals of the CaRE2 center are to reduce cancer disparities in Blacks and Latinos, to train and increase the pool of underrepresented Black and Latino scientists conducting health disparity research, to increase research capacity at FAMU, and to increase cancer disparity research at UF and USC-NCCC. The bi-coastal location offers access to uniquely diverse populations of Blacks and Latinos, facilitating in an unprecedented way, the study of cancer disparities in these incredibly heterogeneous populations. Specifically, the center will focus on studying relevant issues and serving the needs of: (1) Black subpopulations, including American-born, African-born and Caribbean-born Blacks; and (2) Latino subpopulations including Mexican- Americans, Caribbean Latinos, Central and South Americans. This triad brings together investigators and institutions in the two US states that currently have the highest cancer incidence and mortality. The main scientific focus of the center is translational disparities research among heterogeneous minority populations focusing on cancers known for high mortality. We propose to coalesce expertise, infrastructure and share resources in support of 6 innovative translational research projects focused on understanding the biological basis of disparities in Black and Latino populations, capturing the wide heterogeneity within these two groups, with two foundational projects focusing on pancreas cancer (one full, one pilot) and one full project focusing on prostate cancer (Aim 1). Under the leadership of the Research Education Core, we propose to train 100 Black and Latino investigators, including students and early stage investigators (ESI), in translational cancer health disparity research (Aim 2). Existing community partnerships in the Outreach Core will be leveraged to disseminate findings in the Black and Latino community, educate about pancreas and prostate cancer, and improve participation in biomedical research (Aim 3). Finally, the Planning and Evaluation Core will implement a systematic planning and evaluation plan to improve Center effectiveness using innovative strategies (Aim 4). All research projects will be facilitated and enriched by resources and approaches provided by the Tissue Modeling Core and Bioinformatics, Statistical and Methodological Core. All CaRE2 Center’s activities will be centralized and overseen by the Administrative Core. The FAMU-UF-USC partnership is ideally suited to achieve these aims. Both UF and FAMU have worked closely together addressing cancer disparities in Florida Blacks for the last 4 years. USC-NCCC provides complementary and synergistic expertise in cancer disparities research, research training for the Latino population, and expertise in developing culturally-sensitive tools to reduce cancer disparities among Latinos.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	001	6	3/4/2025	COMPETING CONTINUATION	$122,717
2025	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	000	5	3/4/2025	NON-COMPETING CONTINUATION	-$122,717
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $820,069 )
2024	2024	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	004	7	9/6/2024	NON-COMPETING CONTINUATION	$820,069
2024	2023	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	003	6	9/4/2024	COMPETING CONTINUATION	$270,695
2024	2023	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	007	6	9/12/2024	COMPETING CONTINUATION	-$270,695
2024	2023	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90089	LOS ANGELES	USA	Cancer Centers Support Grants	000	6	1/25/2024	COMPETING CONTINUATION	$0
2024	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	006	5	9/12/2024	SUPPLEMENT FOR EXPANSION	$27,122
2024	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	001	5	9/4/2024	NON-COMPETING CONTINUATION	-$243,573
2024	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	005	5	9/12/2024	NON-COMPETING CONTINUATION	$243,573
2024	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Cancer Centers Support Grants	002	5	9/4/2024	SUPPLEMENT FOR EXPANSION	-$27,122
														Subtotal = $820,069

Issue Date FY: 2023 ( Subtotal = $1,145,283 )
2023	2023	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST	LOS ANGELES	CA	90089	LOS ANGELES	USA	Cancer Centers Support Grants	003	6	9/20/2023	COMPETING CONTINUATION	$1,145,283
2023	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST	LOS ANGELES	CA	90089	LOS ANGELES	USA	Cancer Centers Support Grants	000	5	12/8/2022	SUPPLEMENT FOR EXPANSION	$0
2023	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST	LOS ANGELES	CA	90089	LOS ANGELES	USA	Cancer Centers Support Grants	002	5	7/19/2023	NON-COMPETING CONTINUATION	$0
2023	2021	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST	LOS ANGELES	CA	90089	LOS ANGELES	USA	Cancer Centers Support Grants	001	4	7/19/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,145,283

Issue Date FY: 2022 ( Subtotal = $1,242,967 )
2022	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	002	5	9/22/2022	SUPPLEMENT FOR EXPANSION	$124,539
2022	2022	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	001	5	9/13/2022	NON-COMPETING CONTINUATION	$1,118,428
2022	2021	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	000	4	7/19/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,242,967

Issue Date FY: 2021 ( Subtotal = $1,141,251 )
2021	2021	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	001	4	9/3/2021	NON-COMPETING CONTINUATION	$1,141,251
2021	2020	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	000	3	9/3/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $1,141,251

Issue Date FY: 2020 ( Subtotal = $1,471,517 )
2020	2020	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	002	3	9/2/2020	NON-COMPETING CONTINUATION	$1,141,254
2020	2020	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	004	3	9/21/2020	SUPPLEMENT FOR EXPANSION	$164,784
2020	2020	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	003	3	9/18/2020	SUPPLEMENT FOR EXPANSION	$165,479
2020	2019	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	000	2	11/19/2019	NON-COMPETING CONTINUATION	$0
2020	2019	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	001	2	7/27/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,471,517

Issue Date FY: 2019 ( Subtotal = $1,519,503 )
2019	2019	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	000	2	8/30/2019	NON-COMPETING CONTINUATION	$1,107,013
2019	2019	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Aging Research	001	2	9/20/2019	SUPPLEMENT FOR EXPANSION	$412,490
														Subtotal = $1,519,503

Issue Date FY: 2018 ( Subtotal = $1,141,251 )
2018	2018	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90007	LOS ANGELES	USA	Cancer Centers Support Grants	000	1	9/19/2018	NEW	$1,141,251
														Subtotal = $1,141,251

Grand Total All Awards = $8,481,841

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3/3 Florida-California Cancer Research, Education and Engagement (CaRE2) Health Equity Center

Award Number: U54CA233465

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/20/2018

PERIOD OF PERFORMANCE END DATE: 08/31/2028

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