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NIA AD/ADRD Health Care Systems Research Collaboratory

Award Number: U54AG063546
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2019
PERIOD OF PERFORMANCE END DATE: 08/31/2025

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NIA AD/ADRD Health Care Systems Research Collaboratory - Over 6 million Americans live with Alzheimer's disease (AD) or an AD-related dementia (AD/ADRD). Health care systems (HCS) struggle to provide high quality, coordinated, and equitable care to people living with dementia (PLWD) and their care partners (CPs). Scalable and adoptable interventions that are effective in improving the care delivered by HCS to this vulnerable population are desperately needed. Established in September 2019, the National Institute on Aging (NIA) IMbedded Pragmatic Alzheimer's disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory mission is to build the nation’s capacity to conduct embedded pragmatic clinical (ePCTs) of interventions within HCS for PLWD and their CPs. Since its inception, IMPACT has actualized its original aims to advance the conduct of ePCTs, develop and disseminate knowledge, build investigator capacity, and catalyze stakeholder collaboration. IMPACT’s accomplishments and challenges over its initial 5 years inform its next steps and provide rationale for its continuation. A one-year “bridge” supplement between the current award end date of June 30, 2024 and an anticipated competitive renewal start date is requested from July 1, 2024 thru June 30, 2025. The objective of the bridge is to maintain the essential administrative services necessary to supervise and support 36 ongoing projects across IMPACT’s five funding mechanisms (Pilots, Demonstration Projects, Health Care System Scholars, Real World Data Scholars, and Career Development Awards). The administrative services to be maintained during the “bridge” year include: tracking project performance, sustaining IMPACT’s knowledge repository and website, monitoring essential financial functions, maintaining regulatory compliance with the centralized IRB, DSMB, clinical trials.gov, and CROMs. Additionally, for the Long-Term Care Data Cooperative, created under a COVID related IMPACT supplemental project, but now serving investigators conducting nursing home based clinical trials, as well as, observational comparative effectiveness studies, the bridge is essential to keep this initiative operational. IMPACT: IMPACT’s bold vision is to transform the delivery, quality, and outcomes of care provided to Americans living with dementia and their CPs by accelerating the testing and adoption of evidence-based interventions within HCS. Its accomplishments to date provide a strong foundation for this vision, but realizing it will require more time, investment, and innovative approaches. Support for a bridge year, with an anticipated 5-year renewal period to follow, is necessary to maintain essential functions for 36 projects in process and the Long-Term Care Data Cooperative, and ultimately, achieve the full potential of this remarkable national infrastructure and ultimately translate its resources to meaningful improve in the quality of care delivered to PLWD and their CPs.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $16,146,390 )
2025	2025	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	004	6	8/18/2025	COMPETING CONTINUATION	$16,146,390
2025	2024	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	002	5	4/9/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2024	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	006	5	8/25/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	000	5	4/9/2025	NON-COMPETING CONTINUATION	$0
2025	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Allergy and Infectious Diseases Research	001	5	4/9/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Allergy and Infectious Diseases Research	005	5	8/25/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	003	5	8/15/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $16,146,390

Issue Date FY: 2024 ( Subtotal = $4,238,166 )
2024	2024	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	013	5	9/13/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2024	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	012	5	7/19/2024	SUPPLEMENT FOR EXPANSION	$4,238,166
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	006	5	3/5/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	004	5	1/30/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	007	5	4/8/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	001	5	12/12/2023	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	009	5	4/11/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	011	5	5/16/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	005	5	2/7/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	010	5	5/8/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	014	5	9/25/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	002	5	1/3/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	000	5	10/17/2023	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	003	5	1/12/2024	NON-COMPETING CONTINUATION	$0
2024	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Allergy and Infectious Diseases Research	008	5	4/8/2024	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $4,238,166

Issue Date FY: 2023 ( Subtotal = $12,149,488 )
2023	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	006	5	7/11/2023	NON-COMPETING CONTINUATION	$0
2023	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	005	5	7/3/2023	NON-COMPETING CONTINUATION	$11,983,903
2023	2023	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Allergy and Infectious Diseases Research	009	5	9/5/2023	SUPPLEMENT FOR EXPANSION	$199,997
2023	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	002	4	11/25/2022	NON-COMPETING CONTINUATION	$0
2023	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	003	4	2/14/2023	NON-COMPETING CONTINUATION	$0
2023	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	001	4	11/2/2022	NON-COMPETING CONTINUATION	$0
2023	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	004	4	5/9/2023	NON-COMPETING CONTINUATION	$0
2023	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	000	4	10/28/2022	NON-COMPETING CONTINUATION	$0
2023	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Trans-NIH Research Support	008	3	8/7/2023	SUPPLEMENT FOR EXPANSION	-$28,381
2023	2020	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Trans-NIH Research Support	007	2	8/7/2023	SUPPLEMENT FOR EXPANSION	-$6,031
														Subtotal = $12,149,488

Issue Date FY: 2022 ( Subtotal = $12,357,333 ) (Continued on the next page)
2022	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	020	4	8/18/2022	NON-COMPETING CONTINUATION	$0
2022	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	017	4	7/29/2022	NON-COMPETING CONTINUATION	$11,978,889
2022	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	021	4	8/31/2022	SUPPLEMENT FOR EXPANSION	$199,652
2022	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	019	4	8/4/2022	SUPPLEMENT FOR EXPANSION	$2,011,677
2022	2022	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	022	4	9/14/2022	NON-COMPETING CONTINUATION	$0
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	005	3	1/18/2022	NON-COMPETING CONTINUATION	$0
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	016	3	7/29/2022	SUPPLEMENT FOR EXPANSION	-$1,758,135
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	011	3	4/20/2022	NON-COMPETING CONTINUATION	$0
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Trans-NIH Research Support	007	3	3/16/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	012	3	5/17/2022	NON-COMPETING CONTINUATION	$0
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Trans-NIH Research Support	004	3	1/4/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Trans-NIH Research Support	018	3	8/1/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	008	3	3/18/2022	NON-COMPETING CONTINUATION	$0
2022	2021	BROWN UNIVERSITY	1 PROSPECT ST	PROVIDENCE	RI	02912	PROVIDENCE	USA	Aging Research	001	3	12/6/2021	NON-COMPETING CONTINUATION	$0
Grand Total All Awards = $91,722,927

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NIA AD/ADRD Health Care Systems Research Collaboratory

Award Number: U54AG063546

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2019

PERIOD OF PERFORMANCE END DATE: 08/31/2025

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