Wednesday, March 12, 2025 3/12/2025

Continued support for an SPF Macaca nemestrina breeding colony to provide animals to NIH funded HIV research projects

Award Number: U42OD013117
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Abstract The aims of this project are to provide healthy, behaviorally normal, MHC-characterized, SPF pig-tailed macaques for NIH-funded HIV/AIDS related research. We will expand the size of the current SPF breeding colony to increase the numbers of females for breeding and juvenile males and females available for sale to NIH-funded HIV/AIDS investigators both within Johns Hopkins University and at other research institutions. Complete pedigrees and health data are maintained and provided to investigators when animals are being selected for sale. Viral screening includes regular serologic and PCR testing for 4 viral agents: Cercopithecine herpesvirus 1 (B virus), Simian Immunodeficiency Virus (SIV), Simian Retrovirus (SRV), and Simian T- lymphotrophic Virus (STLV). For the past decade the colony has consistently and repeatedly tested negative for these agents. Major histocompatibility (MHC) profiles are performed on all juveniles during the first year of life and are provided to investigators when animals are being selected for purchase. Over the last five years, the colony has produced an average of 51 offspring each year, resulting in an average of 32 animals sold. We estimate that selling 42 animals per year would allow the colony to achieve self-sufficiency, a goal we project we will reach by the end of 2028.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $814,712 )
2025	2025	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	001	18	2/26/2025	NON-COMPETING CONTINUATION	$814,712
2025	2024	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	17	12/17/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $814,712

Issue Date FY: 2024 ( Subtotal = $1,018,391 )
2024	2024	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	002	17	7/11/2024	NON-COMPETING CONTINUATION	$0
2024	2024	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	001	17	6/6/2024	NON-COMPETING CONTINUATION	$203,679
2024	2024	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	17	2/21/2024	NON-COMPETING CONTINUATION	$814,712
														Subtotal = $1,018,391

Issue Date FY: 2023 ( Subtotal = $1,329,350 )
2023	2023	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	004	16	6/7/2023	SUPPLEMENT FOR EXPANSION	$310,959
2023	2023	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	005	16	9/8/2023	NON-COMPETING CONTINUATION	$0
2023	2023	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	003	16	2/18/2023	NON-COMPETING CONTINUATION	$1,018,391
2023	2022	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	002	15	11/14/2022	COMPETING CONTINUATION	$1,045,507
2023	2021	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	001	14	11/14/2022	SUPPLEMENT FOR EXPANSION	-$554,605
2023	2020	THE JOHNS HOPKINS UNIVERSITY	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	14	11/14/2022	NON-COMPETING CONTINUATION	-$490,902
														Subtotal = $1,329,350

Issue Date FY: 2022 ( Subtotal = $1,021,666 )
2022	2022	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	005	15	6/15/2022	COMPETING CONTINUATION	$0
2022	2022	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	001	15	2/18/2022	COMPETING CONTINUATION	$875,938
2022	2022	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	004	15	5/5/2022	COMPETING CONTINUATION	$145,728
2022	2021	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	003	14	4/2/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2021	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	002	14	3/22/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2020	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	14	2/18/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,021,666

Issue Date FY: 2021 ( Subtotal = $554,605 )
2021	2021	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	14	8/20/2021	SUPPLEMENT FOR EXPANSION	$554,605
														Subtotal = $554,605

Issue Date FY: 2020 ( Subtotal = $973,017 )
2020	2020	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	002	14	9/3/2020	NON-COMPETING CONTINUATION	$0
2020	2020	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	14	7/11/2020	NON-COMPETING CONTINUATION	$973,017
2020	2020	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	001	14	7/24/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $973,017

Issue Date FY: 2019 ( Subtotal = $973,017 )
2019	2019	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	13	6/11/2019	NON-COMPETING CONTINUATION	$973,017
														Subtotal = $973,017

Issue Date FY: 2018 ( Subtotal = $1,204,118 )
2018	2018	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	001	12	5/18/2018	NON-COMPETING CONTINUATION	$875,603
2018	2018	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	002	12	6/20/2018	NON-COMPETING CONTINUATION	$97,290
2018	2017	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	11	1/23/2018	COMPETING CONTINUATION	$231,225
														Subtotal = $1,204,118

Issue Date FY: 2017 ( Subtotal = $971,532 )
2017	2017	JOHNS HOPKINS UNIVERSITY, THE	3400 N CHARLES ST	BALTIMORE	MD	21218	BALTIMORE CITY	USA	Research Infrastructure Programs	000	11	8/17/2017	COMPETING CONTINUATION	$971,532
														Subtotal = $971,532

Grand Total All Awards = $8,860,408

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Continued support for an SPF Macaca nemestrina breeding colony to provide animals to NIH funded HIV research projects

Award Number: U42OD013117

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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