Sunday, February 2, 2025 2/2/2025

National Swine Resource and Research Center (NSRRC) Years 21-25

Award Number: U42OD011140
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By:

View Award Abstract

Abstract (Overall) The overall goal of this application is to continue and expand operation of the National Swine Resource and Research Center (NSRRC). The NSRRC is in its 14th year of operation and it has developed the infrastructure needed to assist swine-based research across multiple disciplines, including xenotransplantation. The NSRRC has developed new models of human disease by genetic engineering, it has recruited models created by others, and it has distributed expertise, cells, tissues, organs and pigs to investigators throughout the United States. Since genetic engineering of pigs requires specialized facilities and expertise, the NSRRC provides invaluable services to the research community by using the latest in gene editing technology to create new genetically-engineered swine models. The NSRRC also provides training and education by interacting with individuals, publishing manuscripts and sponsoring workshops and meetings that promote the use of pigs for studying human diseases. The NSRRC has a state-of-the-art building with high biosecurity to house animals free of specific pathogens. The Specific Aims for the upcoming grant period are as follows: 1. To operate the National Swine Research and Resource Center. Functions of the NSRRC will continue to include: a) importation of existing swine models of human health and disease; b) rederivation of pigs to eliminate specific pathogens, and health monitoring to assure maintenance of a specific pathogen-free status; c) cryopreservation and storage of gametes, embryos, and somatic cells to prevent future loss of valuable models; d) distribution of expertise, reagents, cells, tissues, organs, and pathogen-free pigs; and e) use state of the art technology for the creation of new genetically-engineered pigs needed by the biomedical research community. Rigorous quality control will ensure that only high quality genetics are distributed. The NSRRC will also serve as a site for training and educational activities related to research employing swine models. 2. To perform innovative research that will benefit the NSRRC and the biomedical research community. Applied research projects are aimed at improving: a) the cryopreservation of pig reproductive cells and tissues, b) methods for the production of genetically-engineered pigs, c) state-of-the-art testing methods for swine health surveillance, and d) right-size the pig for greater adoption of pig models.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,503,805 )
2024	2024	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	004	22	8/13/2024	NON-COMPETING CONTINUATION	$1,503,805
2024	2023	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	21	5/29/2024	COMPETING CONTINUATION	$0
2024	2023	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	21	4/18/2024	COMPETING CONTINUATION	$260,629
2024	2022	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	20	4/18/2024	NON-COMPETING CONTINUATION	-$157,679
2024	2022	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	20	4/18/2024	SUPPLEMENT FOR EXPANSION	-$102,950
														Subtotal = $1,503,805

Issue Date FY: 2023 ( Subtotal = $2,189,984 )
2023	2023	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	21	8/18/2023	SUPPLEMENT FOR EXPANSION	$294,929
2023	2023	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	21	7/13/2023	SUPPLEMENT FOR EXPANSION	$391,250
2023	2023	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	21	7/4/2023	COMPETING CONTINUATION	$1,503,805
														Subtotal = $2,189,984

Issue Date FY: 2022 ( Subtotal = $2,390,055 )
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	20	8/9/2022	SUPPLEMENT FOR EXPANSION	$466,371
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	20	7/23/2022	NON-COMPETING CONTINUATION	$1,445,966
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	20	8/30/2022	SUPPLEMENT FOR EXPANSION	$477,718
														Subtotal = $2,390,055

Issue Date FY: 2021 ( Subtotal = $2,047,392 )
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	19	7/21/2021	SUPPLEMENT FOR EXPANSION	$309,947
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	19	7/28/2021	SUPPLEMENT FOR EXPANSION	$291,479
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	19	7/20/2021	NON-COMPETING CONTINUATION	$1,445,966
2021	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	18	12/24/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,047,392

Issue Date FY: 2020 ( Subtotal = $1,945,909 )
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	18	8/21/2020	SUPPLEMENT FOR EXPANSION	$499,943
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	18	7/25/2020	NON-COMPETING CONTINUATION	$1,445,966
														Subtotal = $1,945,909

Issue Date FY: 2019 ( Subtotal = $1,853,970 )
2019	2019	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	17	8/22/2019	SUPPLEMENT FOR EXPANSION	$408,004
2019	2019	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	17	8/1/2019	NON-COMPETING CONTINUATION	$1,445,966
2019	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	16	4/19/2019	COMPETING CONTINUATION	$84,298
2019	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	15	4/19/2019	NON-COMPETING CONTINUATION	-$84,298
														Subtotal = $1,853,970

Issue Date FY: 2018 ( Subtotal = $1,445,966 )
2018	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	16	8/31/2018	COMPETING CONTINUATION	$0
2018	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	16	8/27/2018	COMPETING CONTINUATION	$1,445,966
2018	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	15	8/15/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,445,966

Issue Date FY: 2017 ( Subtotal = $1,357,743 )
2017	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	15	5/30/2017	NON-COMPETING CONTINUATION	$1,286,440
2017	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	004	15	9/8/2017	NON-COMPETING CONTINUATION	$71,468
2017	2016	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	14	10/31/2016	EXTENSION WITH OR WITHOUT FUNDS	$370,672
2017	2015	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	13	10/31/2016	NON-COMPETING CONTINUATION	-$370,672
2017	2012	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	10	5/17/2017	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$165
														Subtotal = $1,357,743

Issue Date FY: 2016 ( Subtotal = $1,429,378 )
2016	2016	UNIVERSITY OF MISSOURI, KANSAS CITY	5100 ROCKHILL ROAD	KANSAS CITY	MO	64110	JACKSON	USA	Research Infrastructure Programs	000	14	6/30/2016	EXTENSION WITH OR WITHOUT FUNDS	$1,429,378
														Subtotal = $1,429,378

Issue Date FY: 2015 ( Subtotal = $1,400,790 )
2015	2015	UNIVERSITY OF MISSOURI, KANSAS CITY	5100 ROCKHILL ROAD	KANSAS CITY	MO	64110	JACKSON	USA	Research Infrastructure Programs	000	13	6/20/2015	NON-COMPETING CONTINUATION	$1,400,790
														Subtotal = $1,400,790

Issue Date FY: 2014 ( Subtotal = $1,646,042 )
2014	2014	UNIVERSITY OF MISSOURI, KANSAS CITY	5100 ROCKHILL ROAD	KANSAS CITY	MO	64110	JACKSON	USA	Research Infrastructure Programs	001	12	9/11/2014	SUPPLEMENT FOR EXPANSION	$230,958
2014	2014	UNIVERSITY OF MISSOURI, KANSAS CITY	5100 ROCKHILL ROAD	KANSAS CITY	MO	64110	JACKSON	USA	Research Infrastructure Programs	000	12	7/15/2014	NON-COMPETING CONTINUATION	$1,415,084
														Subtotal = $1,646,042

Issue Date FY: 2013 ( Subtotal = $1,521,403 )
2013	2013	UNIVERSITY OF MISSOURI, KANSAS CITY	5100 ROCKHILL ROAD	KANSAS CITY	MO	64110	JACKSON	USA	Research Infrastructure Programs	001	11	9/13/2013	COMPETING CONTINUATION	$1,429,378
2013	2013	UNIVERSITY OF MISSOURI, KANSAS CITY	5100 ROCKHILL ROAD	KANSAS CITY	MO	64110	JACKSON	USA	Research Infrastructure Programs	002	11	9/14/2013	COMPETING CONTINUATION	$0
2013	2012	UNIVERSITY OF MISSOURI, KANSAS CITY	5100 ROCKHILL ROAD	KANSAS CITY	MO	64110	JACKSON	USA	Research Infrastructure Programs	000	10	3/7/2013	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$92,025
														Subtotal = $1,521,403

Issue Date FY: 2012 ( Subtotal = $1,363,765 ) (Continued on the next page)
2012	2012	UNIVERSITY OF MISSOURI, KANSAS CITY	5100 ROCKHILL ROAD	KANSAS CITY	MO	64110	JACKSON	USA	Research Infrastructure Programs	001	10	9/20/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$200,000
Grand Total All Awards = $22,096,202

Page 1 of 2 (52 items)12

Top

All Categories

About

Search

Reports

Data Submission

Award Information

National Swine Resource and Research Center (NSRRC) Years 21-25

Award Number: U42OD011140

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer