Saturday, December 21, 2024 12/21/2024

The Mutant Mouse Resource and Research Center at The Jackson Laboratory

Award Number: U42OD010921
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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ABSTRACT/PROJECT SUMMARY This application proposes a renewal of the Mouse Mutant Resource and Research Center (MMRRC) at The Jackson Laboratory. Highly sophisticated genome engineering technologies, a well-characterized genome, mammalian physiology and economical husbandry requirements make laboratory mice the mainstay of biomedical research on disease mechanism and for disease modeling. The NIH has recognized that the potential impact of genetically engineered mice for biomedical research cannot be fully realized without a centralized effort to identify, archive, evaluate, characterize, and distribute valuable strains of mice to qualified biomedical researchers. The MMRRC provides this centralized repository function. With over 80 years of mouse genetics and mouse resource experience, The Jackson Laboratory joined the MMRRC in 2009 and since has been a key member of the consortium. This proposal requests on-going support for The Jackson Laboratory as one of the four MMRRC core repositories. As a member of the MMRRC consortium, the Jackson Laboratory will contribute to the development and improvement of consortium wide standard operating procedures. The MMRRC at JAX will follow these mutually agreed upon standard operating procedures to fulfill the goals importation, archiving (through cryopreservation of sperm and/or embryos) and distribution of biomedically important strains of mice and related materials. The MMRRC at JAX also provides related services on a fee for service basis and conducts high risk high return research and model development projects that fit within the overall goals of the consortium.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $1,287,241 )
2024	2024	JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	15	2/15/2024	NON-COMPETING CONTINUATION	$1,029,793
2024	2024	JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	15	5/21/2024	NON-COMPETING CONTINUATION	$257,448
														Subtotal = $1,287,241

Issue Date FY: 2023 ( Subtotal = $1,240,584 )
2023	2023	JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	14	2/23/2023	NON-COMPETING CONTINUATION	$124,059
2023	2023	JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	002	14	3/22/2023	NON-COMPETING CONTINUATION	$0
2023	2023	JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	14	1/13/2023	NON-COMPETING CONTINUATION	$1,116,525
														Subtotal = $1,240,584

Issue Date FY: 2022 ( Subtotal = $1,240,584 )
2022	2022	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	13	1/12/2022	NON-COMPETING CONTINUATION	$1,116,524
2022	2022	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	13	5/5/2022	NON-COMPETING CONTINUATION	$124,060
														Subtotal = $1,240,584

Issue Date FY: 2021 ( Subtotal = $1,737,547 )
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	002	12	7/1/2021	SUPPLEMENT FOR EXPANSION	$491,863
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	12	3/15/2021	NON-COMPETING CONTINUATION	$124,570
2021	2021	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	12	1/23/2021	NON-COMPETING CONTINUATION	$1,121,114
														Subtotal = $1,737,547

Issue Date FY: 2020 ( Subtotal = $1,245,687 )
2020	2020	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	005	11	6/5/2020	COMPETING CONTINUATION	$1,084
2020	2020	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	003	11	5/15/2020	COMPETING CONTINUATION	$4
2020	2020	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	002	11	4/25/2020	COMPETING CONTINUATION	$89,787
2020	2020	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	11	2/6/2020	COMPETING CONTINUATION	$1,155,896
2020	2019	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	10	2/6/2020	NON-COMPETING CONTINUATION	$0
2020	2019	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	004	10	6/5/2020	NON-COMPETING CONTINUATION	-$1,084
														Subtotal = $1,245,687

Issue Date FY: 2019 ( Subtotal = $1,284,255 )
2019	2019	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	10	12/18/2018	NON-COMPETING CONTINUATION	$1,284,255
														Subtotal = $1,284,255

Issue Date FY: 2018 ( Subtotal = $1,589,559 )
2018	2018	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	9	7/14/2018	NON-COMPETING CONTINUATION	$128,427
2018	2018	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	003	9	8/15/2018	SUPPLEMENT FOR EXPANSION	$0
2018	2018	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	002	9	8/6/2018	SUPPLEMENT FOR EXPANSION	$305,304
2018	2018	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	9	2/1/2018	NON-COMPETING CONTINUATION	$1,155,828
														Subtotal = $1,589,559

Issue Date FY: 2017 ( Subtotal = $1,249,834 )
2017	2017	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	8	12/10/2016	NON-COMPETING CONTINUATION	$1,184,053
2017	2017	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	002	8	7/10/2017	NON-COMPETING CONTINUATION	$65,781
2017	2014	THE JACKSON LABORATORY	600 MAIN ST	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	5	5/17/2017	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,249,834

Issue Date FY: 2016 ( Subtotal = $1,331,376 )
2016	2016	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	7	1/27/2016	NON-COMPETING CONTINUATION	$1,331,376
														Subtotal = $1,331,376

Issue Date FY: 2015 ( Subtotal = $1,347,350 )
2015	2015	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	6	2/26/2015	COMPETING CONTINUATION	$1,347,350
														Subtotal = $1,347,350

Issue Date FY: 2014 ( Subtotal = $1,330,906 )
2014	2014	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	002	5	9/4/2014	SUPPLEMENT FOR EXPANSION	$9,975
2014	2014	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	5	3/20/2014	NON-COMPETING CONTINUATION	$120,082
2014	2014	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	5	12/30/2013	NON-COMPETING CONTINUATION	$1,200,849
														Subtotal = $1,330,906

Issue Date FY: 2013 ( Subtotal = $1,268,889 )
2013	2013	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	4	5/17/2013	NON-COMPETING CONTINUATION	$68,044
2013	2013	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	4	12/20/2012	NON-COMPETING CONTINUATION	$1,200,845
														Subtotal = $1,268,889

Issue Date FY: 2012 ( Subtotal = $1,334,274 )
2012	2012	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	001	3	3/21/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2012	2012	JACKSON LABORATORY (THE)	600 MAIN STREET	BAR HARBOR	ME	04609	HANCOCK	USA	Research Infrastructure Programs	000	3	2/27/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,334,274
														Subtotal = $1,334,274

Grand Total All Awards = $17,488,086

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The Mutant Mouse Resource and Research Center at The Jackson Laboratory

Award Number: U42OD010921

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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