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The Mutant Mouse Resource and Research Center at the University of Missouri

Award Number: U42OD010918
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/01/2000
PERIOD OF PERFORMANCE END DATE: 02/28/2030

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The Mutant Mouse Resource and Research Center at the University of Missouri - PROJECT SUMMARY - OVERALL The Mutant Mouse Resource and Research Center (MMRRC) is the nation’s largest public mutant mouse archive and distribution repository organization. The primary goal is to facilitate research by identifying, acquiring, evaluating, characterizing, cryopreserving, and distributing mutant mouse strains to qualified biomedical investigators. The MMRRC was established by the NIH to ensure the preservation, dissemination, and development of valuable mutant mouse lines and data generated by research scientists. The MMRRC is a consortium of four Centers, each hosting an archive and distribution repository, and an Informatics Coordination and Service Center (ICSC) within a trans-national network regionally distributed across the United States. The Centers collectively serve the needs of the nation’s biomedical research community, ensuring access to and optimizing utilization of unique transgenic, knockout, and other genetically modified mutant mice and related biomaterials, services, and new technologies. The Centers collectively import, verify, maintain, and distribute mice, gene-targeted embryonic stem (ES) cells, and germplasm of genetically unique, scientifically valuable mice. Centers also provide services and procedures to assist investigators using genetically altered mice for research. Finally, Centers conduct resource-related research, often collaboratively, to further refine and develop mutant mouse lines to improve the reproducibility and translatability of mouse models for biomedical research. By depositing their mutant mice in repositories at the Centers, NIH-funded investigators fulfill their obligation under the NIH Sharing Policy. In return, each of the Centers strives to preserve the unique genetics, protect the germplasm, assess the genetic quality, and provide these models for the benefit of research scientists and investigators across the nation and the globe. In doing so, the MMRRC preserves the investment NIH made in these models and ensures that valuable mutant mouse lines are available equitably across the biomedical research community, thereby accelerating the pace of rigorous reproducible research and discovery using genetically unique mice.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,180,913 )
2025	2025	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	26	1/31/2025	COMPETING CONTINUATION	$1,180,913
														Subtotal = $1,180,913

Issue Date FY: 2024 ( Subtotal = $1,491,163 )
2024	2024	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	25	2/28/2024	NON-COMPETING CONTINUATION	$1,192,931
2024	2024	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	25	5/14/2024	NON-COMPETING CONTINUATION	$298,232
														Subtotal = $1,491,163

Issue Date FY: 2023 ( Subtotal = $1,491,163 )
2023	2023	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	24	3/3/2023	NON-COMPETING CONTINUATION	$1,491,163
														Subtotal = $1,491,163

Issue Date FY: 2022 ( Subtotal = $1,944,432 )
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	23	8/6/2022	SUPPLEMENT FOR EXPANSION	$453,269
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	23	2/23/2022	NON-COMPETING CONTINUATION	$1,331,201
2022	2022	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	23	5/5/2022	NON-COMPETING CONTINUATION	$159,962
														Subtotal = $1,944,432

Issue Date FY: 2021 ( Subtotal = $2,425,545 )
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	22	7/1/2021	SUPPLEMENT FOR EXPANSION	$466,389
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	22	2/26/2021	NON-COMPETING CONTINUATION	$1,491,163
2021	2021	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	22	8/2/2021	SUPPLEMENT FOR EXPANSION	$467,993
														Subtotal = $2,425,545

Issue Date FY: 2020 ( Subtotal = $1,876,283 )
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	21	7/28/2020	SUPPLEMENT FOR EXPANSION	$385,120
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	004	21	8/4/2020	COMPETING CONTINUATION	$357,584
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	21	5/5/2020	COMPETING CONTINUATION	$232,016
2020	2020	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	21	2/28/2020	COMPETING CONTINUATION	$1,259,147
2020	2019	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	20	8/4/2020	NON-COMPETING CONTINUATION	-$357,584
														Subtotal = $1,876,283

Issue Date FY: 2019 ( Subtotal = $1,420,155 )
2019	2019	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	20	1/19/2019	NON-COMPETING CONTINUATION	$1,420,155
														Subtotal = $1,420,155

Issue Date FY: 2018 ( Subtotal = $1,890,225 )
2018	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	19	8/6/2018	SUPPLEMENT FOR EXPANSION	$470,070
2018	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	19	6/5/2018	NON-COMPETING CONTINUATION	$142,017
2018	2018	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	19	1/10/2018	NON-COMPETING CONTINUATION	$1,278,138
														Subtotal = $1,890,225

Issue Date FY: 2017 ( Subtotal = $1,377,575 )
2017	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	000	18	1/12/2017	NON-COMPETING CONTINUATION	$1,305,072
2017	2017	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	003	18	8/24/2017	NON-COMPETING CONTINUATION	$72,503
2017	2014	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	001	15	7/20/2017	NON-COMPETING CONTINUATION	-$229
2017	2014	UNIVERSITY OF MISSOURI SYSTEM	316 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	Research Infrastructure Programs	002	15	7/20/2017	SUPPLEMENT FOR EXPANSION	$229
														Subtotal = $1,377,575

Issue Date FY: 2016 ( Subtotal = $1,466,079 )
2016	2016	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	001	17	2/8/2016	NON-COMPETING CONTINUATION	$145,009
2016	2016	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	000	17	1/8/2016	NON-COMPETING CONTINUATION	$1,305,070
2016	2016	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	002	17	7/20/2016	SUPPLEMENT FOR EXPANSION	$16,000
														Subtotal = $1,466,079

Issue Date FY: 2015 ( Subtotal = $1,573,093 )
2015	2015	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	001	16	6/15/2015	SUPPLEMENT FOR EXPANSION	$123,014
2015	2015	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	000	16	2/10/2015	COMPETING CONTINUATION	$1,450,079
														Subtotal = $1,573,093

Issue Date FY: 2014 ( Subtotal = $709,699 )
2014	2014	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	003	15	9/6/2014	SUPPLEMENT FOR EXPANSION	$10,000
2014	2014	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	000	15	2/12/2014	NON-COMPETING CONTINUATION	$472,405
2014	2014	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	002	15	8/15/2014	SUPPLEMENT FOR EXPANSION	$98,053
2014	2014	CURATORS OF THE UNIVERSITY OF MISSOURI	5100 Rockhill Road	Kansas City	MO	64110	JACKSON	USA	Research Infrastructure Programs	001	15	3/24/2014	NON-COMPETING CONTINUATION	$129,241
														Subtotal = $709,699

Issue Date FY: 2013 ( Subtotal = $1,365,639 )
2013	2013	CURATORS OF THE UNIVERSITY OF MISSOURI	310 Jesse Hall	Columbia	MO	65211	BOONE	USA	Research Infrastructure Programs	001	14	5/24/2013	NON-COMPETING CONTINUATION	$73,235
2013	2013	CURATORS OF THE UNIVERSITY OF MISSOURI	310 Jesse Hall	Columbia	MO	65211	BOONE	USA	Research Infrastructure Programs	000	14	2/28/2013	NON-COMPETING CONTINUATION	$1,292,404
														Subtotal = $1,365,639

Issue Date FY: 2012 ( Subtotal = $1,436,004 )
2012	2012	CURATORS OF THE UNIVERSITY OF MISSOURI	310 Jesse Hall	Columbia	MO	65211	BOONE	USA	Research Infrastructure Programs	000	13	2/27/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,436,004
														Subtotal = $1,436,004

Grand Total All Awards = $21,647,968

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The Mutant Mouse Resource and Research Center at the University of Missouri

Award Number: U42OD010918

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/01/2000

PERIOD OF PERFORMANCE END DATE: 02/28/2030

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