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Maintenance of an SPF Macaque Breeding Colony for AIDS Research

Award Number: U42OD010568
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/09/2001
PERIOD OF PERFORMANCE END DATE: 01/31/2029

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Maintenance of an SPF Macaque Breeding Colony for AIDS Research - PROJECT SUMMARY/ABSTRACT – OVERALL The Tulane National Primate Research Center (TNPRC) has one of the largest rhesus monkey breeding colonies in the United States. The objective of this application is to request funds for continued support and maintenance of the U42-supported specific pathogen-free (SPF) Indian-origin rhesus monkey breeding colony at the TNPRC. We will moderately increase production over the next few years due to recent developments in funding and animal demand. The specific aims address the components specified in the Notice of Funding Opportunity (NOFO) and are divided into the overall program description, husbandry core, viral testing core, and MHC genetic typing core. Program income and TNPRC funds will be used to fund components of the program not covered by grant funds, including per diem for any colony animals in excess of the animals supported by this application, additional testing required for those animals, infrastructure repairs and improvements, veterinary clinical and pathology support, behavioral management support, and portions of the genetic testing. Specific Aims: Overall. To maintain the existing SPF colony and distribute available animals to the NIH-funded HIV/AIDS research community. Husbandry and Management Core. To provide husbandry and veterinary care for the SPF breeding colony. This includes a robust program for clinical veterinary medical care and behavioral management. The colony has reached a mature, self-sustaining status with ideal demographics for production that allow making up to 150 animals available for research assignment each year. Program income generated by the sale of animals will be returned to an account for use in supporting the aims of the grant. Viral Testing Core. To assure the SPF status of the colony through continued viral testing of existing breeding colony animals and all offspring. Continue to expand characterization of the colony beyond the required 4 viruses to include agents such as measles virus, SARS-CoV-2, Trypanosoma cruzi, and other emerging infectious diseases that threaten nonhuman primates. MHC Genetic Typing Core. To continue genetic analysis and MHC typing of the SPF colony and provide expanded genetic characterization through enhanced techniques.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,172,603 )
2025	2025	THE ADMINISTRATORS OF TULANE EDUCATIONAL FUND	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	23	12/31/2024	COMPETING CONTINUATION	$1,172,603
														Subtotal = $1,172,603

Issue Date FY: 2024 ( Subtotal = $1,415,801 )
2024	2024	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	22	1/24/2024	NON-COMPETING CONTINUATION	$1,132,641
2024	2024	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	001	22	5/14/2024	NON-COMPETING CONTINUATION	$283,160
														Subtotal = $1,415,801

Issue Date FY: 2023 ( Subtotal = $1,834,571 )
2023	2023	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	21	1/14/2023	NON-COMPETING CONTINUATION	$1,274,222
2023	2023	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	003	21	8/25/2023	SUPPLEMENT FOR EXPANSION	$418,770
2023	2023	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	002	21	7/29/2023	NON-COMPETING CONTINUATION	$0
2023	2023	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	001	21	2/22/2023	NON-COMPETING CONTINUATION	$141,579
														Subtotal = $1,834,571

Issue Date FY: 2022 ( Subtotal = $1,415,801 )
2022	2022	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	20	1/12/2022	NON-COMPETING CONTINUATION	$1,274,221
2022	2022	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	001	20	5/5/2022	NON-COMPETING CONTINUATION	$141,580
														Subtotal = $1,415,801

Issue Date FY: 2021 ( Subtotal = $1,415,801 )
2021	2021	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	19	1/20/2021	COMPETING CONTINUATION	$1,213,543
2021	2021	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	003	19	8/21/2021	COMPETING CONTINUATION	$25,008
2021	2021	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	001	19	3/24/2021	COMPETING CONTINUATION	$202,258
2021	2020	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	002	18	8/21/2021	NON-COMPETING CONTINUATION	-$25,008
														Subtotal = $1,415,801

Issue Date FY: 2020 ( Subtotal = $1,348,382 )
2020	2020	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	001	18	3/4/2020	NON-COMPETING CONTINUATION	$134,839
2020	2020	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	18	1/15/2020	NON-COMPETING CONTINUATION	$1,213,543
														Subtotal = $1,348,382

Issue Date FY: 2019 ( Subtotal = $1,348,362 )
2019	2019	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	001	17	2/5/2019	NON-COMPETING CONTINUATION	$0
2019	2019	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	17	1/11/2019	NON-COMPETING CONTINUATION	$1,348,382
2019	2016	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	002	14	6/26/2019	EXTENSION WITH OR WITHOUT FUNDS	-$20
														Subtotal = $1,348,362

Issue Date FY: 2018 ( Subtotal = $1,348,382 )
2018	2018	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	16	1/13/2018	NON-COMPETING CONTINUATION	$1,213,543
2018	2018	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	001	16	6/8/2018	NON-COMPETING CONTINUATION	$134,839
														Subtotal = $1,348,382

Issue Date FY: 2017 ( Subtotal = $1,723,932 )
2017	2017	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Trans-NIH Research Support	004	15	9/7/2017	SUPPLEMENT FOR EXPANSION	$375,550
2017	2017	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	003	15	9/2/2017	COMPETING CONTINUATION	$74,234
2017	2017	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	000	15	3/16/2017	COMPETING CONTINUATION	$1,274,148
2017	2017	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	002	15	3/27/2017	COMPETING CONTINUATION	$16,878
2017	2016	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	Research Infrastructure Programs	001	14	3/27/2017	EXTENSION WITH OR WITHOUT FUNDS	-$16,878
														Subtotal = $1,723,932

Issue Date FY: 2016 ( Subtotal = $1,348,382 )
2016	2016	TULANE UNIVERSITY, DELTA REGIONAL PRIMATE CENTER	18703 Three Rivers Road	COVINGTON	LA	70433	SAINT TAMMANY	USA	Research Infrastructure Programs	001	14	2/3/2016	EXTENSION WITH OR WITHOUT FUNDS	$134,837
2016	2016	TULANE UNIVERSITY, DELTA REGIONAL PRIMATE CENTER	18703 Three Rivers Road	COVINGTON	LA	70433	SAINT TAMMANY	USA	Research Infrastructure Programs	000	14	12/9/2015	EXTENSION WITH OR WITHOUT FUNDS	$1,213,545
														Subtotal = $1,348,382

Issue Date FY: 2015 ( Subtotal = $1,321,413 )
2015	2015	TULANE UNIVERSITY, DELTA REGIONAL PRIMATE CENTER	18703 Three Rivers Road	COVINGTON	LA	70433	SAINT TAMMANY	USA	Research Infrastructure Programs	000	13	2/23/2015	NON-COMPETING CONTINUATION	$1,321,413
														Subtotal = $1,321,413

Issue Date FY: 2014 ( Subtotal = $1,334,897 )
2014	2014	TULANE UNIVERSITY, DELTA REGIONAL PRIMATE CENTER	18703 Three Rivers Road	COVINGTON	LA	70433	SAINT TAMMANY	USA	Research Infrastructure Programs	001	12	4/9/2014	NON-COMPETING CONTINUATION	$121,354
2014	2014	TULANE UNIVERSITY, DELTA REGIONAL PRIMATE CENTER	18703 Three Rivers Road	COVINGTON	LA	70433	SAINT TAMMANY	USA	Research Infrastructure Programs	000	12	12/25/2013	NON-COMPETING CONTINUATION	$1,213,543
														Subtotal = $1,334,897

Issue Date FY: 2013 ( Subtotal = $1,348,382 )
2013	2013	TULANE UNIVERSITY, DELTA REGIONAL PRIMATE CENTER	18703 Three Rivers Road	COVINGTON	LA	70433	SAINT TAMMANY	USA	Research Infrastructure Programs	001	11	5/18/2013	COMPETING CONTINUATION	$149,822
2013	2013	TULANE UNIVERSITY, DELTA REGIONAL PRIMATE CENTER	18703 Three Rivers Road	COVINGTON	LA	70433	SAINT TAMMANY	USA	Research Infrastructure Programs	000	11	1/10/2013	COMPETING CONTINUATION	$1,198,560
														Subtotal = $1,348,382

Grand Total All Awards = $18,376,709

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Maintenance of an SPF Macaque Breeding Colony for AIDS Research

Award Number: U42OD010568

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/09/2001

PERIOD OF PERFORMANCE END DATE: 01/31/2029

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