Monday, August 18, 2025 8/18/2025

Multi-ethnic Observational Study in American Asian and Pacific Islander Communities (MOSAAIC) Mental Health Administrative Supplement

Award Number: U24HL169645
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2023
PERIOD OF PERFORMANCE END DATE: 07/31/2026

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Multi-ethnic Observational Study in American Asian and Pacific Islander Communities (MOSAAIC) Mental Health Administrative Supplement - Project Summary The Multiethnic Observational Study in American Asian and Pacific Islander Communities (MOSAAIC) is a groundbreaking study focused on understanding cardiometabolic and mental health disparities in Asian Americans, Native Hawaiians, and Pacific Islanders. By enrolling 10,000 participants, the study aims to uncover risk factors and improve health outcomes. We collect extensive data through clinical exams, biological samples, and annual follow-ups. We propose this administrative supplement to enhance the rigor of the MOSAAIC cohort study’s research relating to the burden of mental health conditions among Asian and Pacific Islander communities and the relationship of mental health with cardiovascular disease risk. The goals of the administrative supplement are to assess the psychometric properties of standardized mental health survey instruments when administered in five Asian languages and to develop protocols to address suicidal ideation, especially in underserved communities. These protocols will be culturally and geographically tailored to ensure appropriate responses across diverse field centers. To achieve these aims, the study will rigorously evaluate mental health instruments' psychometric properties and ensure their accuracy and cultural relevance. The study will also adapt mental health tools for non-English- speaking populations. The development of the suicidal ideation protocol will involve collaboration with experts in psychiatry and psychology to ensure culturally sensitive crisis management training. This approach strengthens the scientific integrity and ethical standards of the parent MOSAAIC study by enhancing participant safety, wellbeing, and data quality. The proposed enhancements will also contribute to the long-term goals of informing health policies and improving health interventions for these historically underrepresented communities. The project aligns with the parent grant’s objectives, advancing the research capacity needed to address significant health disparities.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $9,053,526 )
2025	2025	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	002	3	8/1/2025	NON-COMPETING CONTINUATION	$8,753,539
2025	2025	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	003	3	8/12/2025	SUPPLEMENT FOR EXPANSION	$299,987
2025	2024	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	000	2	10/10/2024	SUPPLEMENT FOR EXPANSION	$0
2025	2024	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	001	2	10/10/2024	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $9,053,526

Issue Date FY: 2024 ( Subtotal = $4,983,539 )
2024	2024	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	002	2	9/4/2024	SUPPLEMENT FOR EXPANSION	$372,945
2024	2024	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	001	2	7/24/2024	NON-COMPETING CONTINUATION	$4,168,697
2024	2024	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	003	2	9/10/2024	SUPPLEMENT FOR EXPANSION	$441,897
2024	2023	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	000	1	6/28/2024	NEW	$0
														Subtotal = $4,983,539

Issue Date FY: 2023 ( Subtotal = $2,599,968 )
2023	2023	FRED HUTCHINSON CANCER CENTER	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cardiovascular Diseases Research	000	1	8/4/2023	NEW	$2,599,968
														Subtotal = $2,599,968

Grand Total All Awards = $16,637,033

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Multi-ethnic Observational Study in American Asian and Pacific Islander Communities (MOSAAIC) Mental Health Administrative Supplement

Award Number: U24HL169645

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2023

PERIOD OF PERFORMANCE END DATE: 07/31/2026

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