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USC Facebase IV Craniofacial Development and Dysmorpholoy Data Management and Integration Hub (FaceBase IV))

Award Number: U24DE034163
ORGANIZATION: NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2024
PERIOD OF PERFORMANCE END DATE: 05/31/2029

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USC Facebase IV Craniofacial Development and Dysmorpholoy Data Management and Integration Hub (FaceBase IV)) - Dental, Oral and Craniofacial health (DOC) plays a significant factor in the overall well-being of the population. About half of all birth defects are associated with craniofacial malformations. Many other genetic conditions manifest themselves via phenotypes in the face and skull and are associated with communication disorders, neurological development and other factors. Furthermore, oral health plays a significant role in overall human health. Driven by the importance of DOC research to overall human health, the National Institute of Dental and Craniofacial Research (NIDCR) established the FaceBase Consortium in 2009 to advance research relevant to the NIDCR mission by creating comprehensive datasets of craniofacial development and dysmorphologies in order to disseminate these datasets to the wider craniofacial research community and support reuse of data for new research projects and collaborations. Since its creation, FaceBase has become a central data repository resource funded for dental and craniofacial researchers. We propose to build on the success of FaceBase to date to 1) expand our community outreach, training, and education resources by fostering an active community of users across the translational spectrum of Dental, Oral and Craniofacial (DOC) research and related disciplines trained in use of FaceBase, 2) enhance FaceBase services to efficiently serve a growing community ranging from single investigators to multi-consortia, and empower scientists across the translational spectrum of DOC research and other relevant health studies to advice their research using FAIR, TRUSTworthy, scientifically robust, data-driven, and AI/ML/DL-ready resources, and 3) build on our robust and agile project management structure to meet the new requirements of the extended use cases and community envisioned by this proposal.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $3,923,500 )
2025	2025	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Oral Diseases and Disorders Research	001	1	12/20/2024	SUPPLEMENT FOR EXPANSION	$474,500
2025	2025	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Oral Diseases and Disorders Research	003	2	5/16/2025	NON-COMPETING CONTINUATION	$3,449,000
2025	2024	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Oral Diseases and Disorders Research	000	1	12/20/2024	NEW	$0
2025	2024	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Oral Diseases and Disorders Research	002	1	5/16/2025	NEW	$0
														Subtotal = $3,923,500

Issue Date FY: 2024 ( Subtotal = $2,500,000 )
2024	2024	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Oral Diseases and Disorders Research	001	1	8/28/2024	NEW	$0
2024	2024	UNIVERSITY OF SOUTHERN CALIFORNIA	3720 S FLOWER ST FL 3	LOS ANGELES	CA	90033	LOS ANGELES	USA	Oral Diseases and Disorders Research	000	1	8/15/2024	NEW	$2,500,000
														Subtotal = $2,500,000

Grand Total All Awards = $6,423,500

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USC Facebase IV Craniofacial Development and Dysmorpholoy Data Management and Integration Hub (FaceBase IV))

Award Number: U24DE034163

ORGANIZATION: NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2024

PERIOD OF PERFORMANCE END DATE: 05/31/2029

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