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Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research

Award Number: U24CA274494
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/14/2022
PERIOD OF PERFORMANCE END DATE: 08/31/2027

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Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research - Project Summary Systems Biology has been an instrumental approach to overcoming challenges in biomedical research, where solutions arise from interdisciplinary efforts, shared resources (data, tools, models, expertise) and integrative analyses. The NCI Division of Cancer Biology (DCB) has created multiple consortia comprising interdisciplinary communities of scientists who aim to integrate approaches, data, and tools to address important questions in basic and translational cancer research. The Multi-Consortia Coordinating (MC2) Center for Cancer Biology will work across programs to motivate engagement and collaboration, support resource sharing, and disseminate knowledge and resources to the broader scientific community. The MC2 Center will operate through three hubs. The Collaboration Hub will use evidence-based strategies to catalyze interactions and new collaborations. An evaluation framework will be developed with quantitative and qualitative metrics to ensure the center continuously improves its impact. Community engagement activities will include working groups, special interest groups, and annual cross-consortia meetings. To facilitate sharing of resources from DCB programs, the Resource Coordination Hub will ensure all resources are findable, accessible, interoperable and reusable (FAIR); it will identify or develop open and FAIR standards and best practices; provide training on how to implement these standards and practices in the cancer research community; and provide tooling and interfaces to facilitate resource sharing, curation, and deposition in public repositories. Finally, the Outreach Hub will enhance dissemination of knowledge and resources through training materials to maximize utilization of tools and short courses and workshops that bring concepts and resources from across the DCB programs together, enabling the broader community to experience the power of an integrative interdisciplinary approach to cancer. The Cancer Complexity Knowledge Portal will continue to provide open access to all data, tools, and other resources generated through the DCB and MC2, highlighting discoveries and enabling exploration into the many valuable resources generated by DCB programs.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	000	4	2/25/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $1,875,140 )
2025	2025	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	001	4	9/1/2025	NON-COMPETING CONTINUATION	$1,875,140
2025	2024	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	000	3	4/9/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,875,140

Issue Date FY: 2024 ( Subtotal = $1,793,657 )
2024	2024	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	005	3	8/20/2024	NON-COMPETING CONTINUATION	$1,793,657
2024	2023	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	000	2	2/21/2024	NON-COMPETING CONTINUATION	$0
2024	2023	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	002	2	8/5/2024	NON-COMPETING CONTINUATION	$0
2024	2023	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	004	2	8/8/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2023	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	003	2	8/8/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2023	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	001	2	3/18/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,793,657

Issue Date FY: 2023 ( Subtotal = $2,289,564 )
2023	2023	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	001	2	8/21/2023	SUPPLEMENT FOR EXPANSION	$152,500
2023	2023	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	000	2	8/18/2023	NON-COMPETING CONTINUATION	$1,867,064
2023	2023	SAGE BIONETWORKS	2901 3RD AVE STE 330	SEATTLE	WA	98121	KING	USA	Cancer Biology Research	002	2	9/12/2023	SUPPLEMENT FOR EXPANSION	$270,000
														Subtotal = $2,289,564

Issue Date FY: 2022 ( Subtotal = $1,980,301 )
2022	2022	SAGE BIONETWORKS	1100 FAIRVIEW AVE N	SEATTLE	WA	98109	KING	USA	Cancer Biology Research	000	1	9/14/2022	NEW	$1,980,301
														Subtotal = $1,980,301

Grand Total All Awards = $7,938,662

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Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research

Award Number: U24CA274494

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/14/2022

PERIOD OF PERFORMANCE END DATE: 08/31/2027

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