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Support for Human Specimen Banking in NCI-Sponsored Clinical Trials-(CGB)

Award Number: U24CA114766
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/03/2005
PERIOD OF PERFORMANCE END DATE: 03/31/2014

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Support for Human Specimen Banking in NCI-Sponsored Clinical Trials-(CGB) - DESCRIPTION (provided by applicant): Over 90% of United States and Canadian children and adolescents with cancer are enrolled in Children's Oncology Group (COG) clinical trials with no racial, ethnic or geographic bias to registration, allowing for near- population-based clinical, translational and basic research. Clinical trials conducted by COG and its antecedent organizations have played a major role in these advances and will continue to drive the improvements projected to come in the next decade. The biospecimens collected during these clinical treatment trials are crucial to their success. These biospecimens are sent to centralized laboratories for clinical testing and banking for future research use. The Biopathology Center (BPC) is part of the Research Institute at Nationwide Children's Hospital in Columbus, Ohio and houses the COG Solid Tissue Bank as well as the COG ALL Molecular Reference Laboratory and Bank. The COG AML Reference Laboratory and Bank is located at the Fred Hutchinson Cancer Research Center Seattle, Washington. Currently, the BPC is federally funded to serve several clients (including the Pediatric Division of the Cooperative Human Tissue Network [pCHTN], and the biobanking efforts of the Gynecologic Oncology Group [GOG], the Childhood Cancer Survivor Study [CCSS], and the Cancer Therapy Evaluation Program [CTEP]). To accomplish this, the banks continue to work with the aims of the original grant submission in 2004. 1. Establish collection, storage and quality control procedures for tissue banking in pediatric cancer patients that are near-population-based. 2. Ensure proper storage and quality control procedures for pediatric tissue bank biospecimens that promote outstanding retrospective translational research. 3. Ensure proper administration of tissue bank resources to facilitate investigator access to biospecimens. 4. Promote linkage of tissue bank resources to existing demographic, clinical, and biological, treatment and outcome data. 5. Optimize utilization of finite tissue bank resources utilizing emerging technologies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2017 ( Subtotal = $0 )
2017	2014	RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL	700 CHILDRENS DR	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	000	8	8/11/2017	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $0

Issue Date FY: 2016 ( Subtotal = $0 )
2016	2013	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	432052696	FRANKLIN	USA	Cancer Detection and Diagnosis Research	000	8	9/22/2016	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2015 ( Subtotal = $0 )
2015	2013	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	000	8	5/18/2015	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2014 ( Subtotal = $1,510,732 )
2014	2014	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	000	8	6/5/2014	SUPPLEMENT FOR EXPANSION	$1,510,732
2014	2013	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	001	8	6/11/2014	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,510,732

Issue Date FY: 2013 ( Subtotal = $1,696,292 )
2013	2013	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	003	8	9/24/2013	NON-COMPETING CONTINUATION	$137,100
2013	2013	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	001	8	4/1/2013	NON-COMPETING CONTINUATION	$738,487
2013	2013	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	002	8	6/28/2013	NON-COMPETING CONTINUATION	$809,330
2013	2012	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	000	7	3/8/2013	SUPPLEMENT FOR EXPANSION	$11,375
														Subtotal = $1,696,292

Issue Date FY: 2012 ( Subtotal = $3,317,650 )
2012	2012	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	004	7	8/29/2012	SUPPLEMENT FOR EXPANSION	$1,488,625
2012	2012	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	005	7	9/18/2012	SUPPLEMENT FOR EXPANSION	$99,862
2012	2012	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	003	7	8/24/2012	SUPPLEMENT FOR EXPANSION	$400,001
2012	2012	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	001	7	7/18/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$1,329,162
2012	2012	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	002	7	7/25/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,329,162
2012	2012	Research Institute at Nationwide`s Children`s Hospital	700 CHILDREN`S DRIVE	COLUMBUS	OH	43205	FRANKLIN	USA	Cancer Detection and Diagnosis Research	000	7	6/21/2012	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,329,162
														Subtotal = $3,317,650

Issue Date FY: 2011 ( Subtotal = $1,195,618 )
2011	2011	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	006	5	9/23/2011	SUPPLEMENT FOR EXPANSION	-$672,242
2011	2011	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	002	5	4/27/2011	SUPPLEMENT FOR EXPANSION	$1,050,758
2011	2011	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	007	6	9/23/2011	COMPETING CONTINUATION	$817,102
2011	2010	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	004	5	9/22/2011	SUPPLEMENT FOR EXPANSION	$0
2011	2010	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	001	5	4/27/2011	SUPPLEMENT FOR EXPANSION	$0
2011	2009	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	005	5	9/22/2011	NON-COMPETING CONTINUATION	$0
2011	2009	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	003	5	4/27/2011	NON-COMPETING CONTINUATION	$0
2011	2009	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	000	5	2/2/2011	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,195,618

Issue Date FY: 2010 ( Subtotal = $1,195,618 )
2010	2010	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	002	5	9/8/2010	SUPPLEMENT FOR EXPANSION	$1,195,618
2010	2010	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	003	5	9/17/2010	SUPPLEMENT FOR EXPANSION	$0
2010	2009	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	000	5	1/21/2010	NON-COMPETING CONTINUATION	$0
2010	2009	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	001	5	1/27/2010	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,195,618

Issue Date FY: 2009 ( Subtotal = $1,195,618 )
2009	2009	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	001	5	3/20/2009	NON-COMPETING CONTINUATION	$1,195,618
2009	2008	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	000	4	3/9/2009	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,195,618

Issue Date FY: 2008 ( Subtotal = $993,896 )
2008	2008	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	000	4	4/2/2008	NON-COMPETING CONTINUATION	$993,896
														Subtotal = $993,896

Issue Date FY: 2007 ( Subtotal = $1,133,628 )
2007	2007	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	000	3	4/5/2007	NON-COMPETING CONTINUATION	$1,133,628
														Subtotal = $1,133,628

Issue Date FY: 2006 ( Subtotal = $1,155,233 )
2006	2006	NATIONAL CHILDHOOD CANCER FOUNDATION	POST OFFICE BOX 60012	ARCADIA	CA	91006	LOS ANGELES	USA	Cancer Detection and Diagnosis Research	000	2	8/18/2006	NON-COMPETING CONTINUATION	$1,155,233
														Subtotal = $1,155,233

Grand Total All Awards = $13,394,285

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Support for Human Specimen Banking in NCI-Sponsored Clinical Trials-(CGB)

Award Number: U24CA114766

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/03/2005

PERIOD OF PERFORMANCE END DATE: 03/31/2014

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