Tuesday, May 13, 2025 5/13/2025

The plasticity of well-being: A research network to define, measure and promote human flourishing

Award Number: U24AT011289
ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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The plasticity of well-being: A research network to define, measure and promote human flourishing - PROJECT SUMMARY/ABSTRACT This U24 application is written in response to RFA-AT-20-003 to establish a high-priority research network on emotional well-being (EWB). While psychological research on well-being has dramatically increased over the past 15 years, virtually all of this work has been descriptive and has not emphasized the “how” of well-being: How might well-being be cultivated? In addition, virtually all of the extant work on the correlates of individual differences in well-being has used responses on retrospective questionnaires as the primary tool to assess well-being. While there have been exciting findings, particularly relating individual differences in well-being to various indices of physical health, many questions remain and methodological limitations plague the validity of this work. This U24 network will assemble a highly multi-disciplinary group of 10 investigators across 3 (or more in the future) institutions to significantly advance our understanding of the “how” of EWB, identify the core plastic constituents of EWB, specify and/or develop robust measures of these constituents at biological, behavioral and experiential levels of analysis and characterize the plasticity of these constituents. The measurement strategy will ultimately focus on the development of technology-based passive measures of EWB that require no explicit user input and are highly scalable. The network will also focus its efforts on the development and evaluation of programs to train EWB and will assess whether such programs might serve as prevention strategies. The network will consist of scientists and scholars from a broad range of fields including psychology, neuroscience, electrical and computer engineering, population health and biology, computer science and the humanities. These scientists and scholars will focus on the following major aims: Aim 1: To arrive at a core consensus of the minimal set of constituents that can be described and measured at biological, behavioral and experiential levels that constitute the plastic elements of EWB and to specify already existing measures and /or develop novel measures of each of these constructs at each level of analysis. Aim 2: Using the active measures described in Aim 1, to develop passive measures using digital technologies of at least two of the core constituents of well-being. Aim 3: To develop pilot projects specifically focusing on prevention strategies for learning well-being in various samples. The network will train new investigators and bring established investigators into this new field, disseminate a framework for understanding the plasticity of well- being, a toolbox of measures for assessing the plasticity of components of well-being, and several pilot datasets that showcase the novel passive and field-friendly biological measures. In these ways, the network will dramatically accelerate progress in the nascent field of EWB.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	000	4	3/20/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $599,605 )
2024	2024	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	001	4	5/13/2024	NON-COMPETING CONTINUATION	$59,961
2024	2024	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	000	4	2/13/2024	NON-COMPETING CONTINUATION	$539,644
2024	2024	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	002	4	9/19/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $599,605

Issue Date FY: 2023 ( Subtotal = $607,380 )
2023	2023	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	000	3	1/19/2023	NON-COMPETING CONTINUATION	$607,380
2023	2023	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	001	3	4/19/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $607,380

Issue Date FY: 2022 ( Subtotal = $615,155 )
2022	2022	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	001	2	5/5/2022	NON-COMPETING CONTINUATION	$61,517
2022	2022	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6301	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	000	2	1/27/2022	NON-COMPETING CONTINUATION	$553,638
														Subtotal = $615,155

Issue Date FY: 2021 ( Subtotal = $620,542 )
2021	2021	UNIVERSITY OF WISCONSIN SYSTEM	21 N PARK ST STE 6401	MADISON	WI	53715	DANE	USA	Research and Training in Complementary and Integrative Health	000	1	1/29/2021	NEW	$620,542
														Subtotal = $620,542

Grand Total All Awards = $2,442,682

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The plasticity of well-being: A research network to define, measure and promote human flourishing

Award Number: U24AT011289

ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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