Saturday, December 21, 2024 12/21/2024

Developing and Disseminating the Approach to Defining, Classifying, and Monitoring Adverse and Serious Adverse Events in Clinical Trials involving Older, Seriously Ill Populations

Award Number: U24AG059624
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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View Award Abstract

The Coordinating Center (CC) for the Older Americans Independence Centers (OAIC) Program plans, initiates, facilitates, and coordinates activities that maximize OAIC collaborations. Our guiding philosophy is to focus on activities that promise high impact but would be difficult for individual OAICs to achieve on their own, and which result in collaborations that unlock synergy, thereby making the whole (the OAIC program) greater than its parts (the individual centers and investigators). Our preliminary data show that the present cycle has been the most successful and productive to date. The proposed new cycle will build on and extend these accomplishments with initiatives embedded in the following four Specific Aims, which were informed by our preliminary data, including our evaluation processes and our structured interviews with three key groups of stakeholders: directors of all 15 OAICs, a panel of early career investigators, and NIA program officials. Specific Aim 1. Enhance communications and coordination within the OAIC program and with the greater aging research community. Specific Aim 2. Facilitate and promote OAIC-themed collaborative research. Specific Aim 3. Enhance the development of the next generation of researchers in aging. Specific Aim 4. Accelerate implementation of key OAIC research findings into member health care systems and their communities. We will achieve these aims by capitalizing on: 1) our 17 years of experience and earned trust in progressively building collaborations; 2) an expanded, multi-disciplinary, cohesive, multi-institutional team of experienced leaders with complementary skills and well-defined roles; 3) our well established processes, including four working groups and inclusion of key stakeholders; 4) regular input and guidance from the OAIC Directors Committee and NIA program officials; and 5) continously evaluating progress toward each aim and overall goals of the program. This proposed renewal of the CC will further increase the breadth and depth of OAIC collaboration, provide vital new research opportunities, particularly for early career investigators, promote career development of new investigators, and disseminate key OAIC research findings to improve the healthcare of older Americans.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $819,414 )
2024	2024	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	004	7	7/9/2024	NON-COMPETING CONTINUATION	$640,000
2024	2024	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	005	7	7/16/2024	SUPPLEMENT FOR EXPANSION	$179,414
2024	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	003	6	6/27/2024	COMPETING CONTINUATION	$0
2024	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	002	6	2/6/2024	COMPETING CONTINUATION	$0
2024	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	001	6	1/22/2024	COMPETING CONTINUATION	$444,211
2024	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	000	5	1/22/2024	NON-COMPETING CONTINUATION	-$444,211
														Subtotal = $819,414

Issue Date FY: 2023 ( Subtotal = $640,000 )
2023	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	003	6	8/30/2023	COMPETING CONTINUATION	$0
2023	2023	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	002	6	5/11/2023	COMPETING CONTINUATION	$640,000
2023	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	001	5	5/4/2023	NON-COMPETING CONTINUATION	$0
2023	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	000	5	12/30/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $640,000

Issue Date FY: 2022 ( Subtotal = $549,792 )
2022	2022	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	001	5	8/12/2022	NON-COMPETING CONTINUATION	$549,792
2022	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	000	4	1/27/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $549,792

Issue Date FY: 2021 ( Subtotal = $782,067 )
2021	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	001	4	7/12/2021	NON-COMPETING CONTINUATION	$549,792
2021	2021	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	002	4	8/20/2021	SUPPLEMENT FOR EXPANSION	$232,275
2021	2020	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	000	3	3/31/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $782,067

Issue Date FY: 2020 ( Subtotal = $761,033 )
2020	2020	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	002	3	5/21/2020	SUPPLEMENT FOR EXPANSION	$146,924
2020	2020	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	001	3	5/13/2020	NON-COMPETING CONTINUATION	$614,109
2020	2019	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	000	2	1/24/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $761,033

Issue Date FY: 2019 ( Subtotal = $649,775 )
2019	2019	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	000	2	5/3/2019	NON-COMPETING CONTINUATION	$500,000
2019	2019	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	001	2	9/16/2019	SUPPLEMENT FOR EXPANSION	$149,775
														Subtotal = $649,775

Issue Date FY: 2018 ( Subtotal = $500,000 )
2018	2018	WAKE FOREST UNIVERSITY HEALTH SCIENCES	MEDICAL CENTER BLVD	WINSTON SALEM	NC	27157	FORSYTH	USA	Aging Research	000	1	7/3/2018	NEW	$500,000
														Subtotal = $500,000

Grand Total All Awards = $4,702,081

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Developing and Disseminating the Approach to Defining, Classifying, and Monitoring Adverse and Serious Adverse Events in Clinical Trials involving Older, Seriously Ill Populations

Award Number: U24AG059624

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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