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Multidisciplinary Implementation Research for malaria control and elimination in West Africa

Award Number: U19AI129387
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/18/2017
PERIOD OF PERFORMANCE END DATE: 03/31/2029

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Multidisciplinary Implementation Research for malaria control and elimination in West Africa - Abstract Despite a substantial reduction in the incidence and deaths related to malaria in sub-Sahara Africa, the region still carries a disproportionate share of the global burden of malaria. The overall goal of this ICEMR program is to understand the persistence of malaria in the context of the wide deployment of control interventions and provide evidence-based approaches for developing optimal combinations of control strategies for interrupting residual malaria transmission. We will characterize critical barriers related to changing epidemiological patterns and drug and insecticide resistance to develop contextually tailored interventions to address the evolving needs of malaria control programs. This ICEMR encompasses 3 Projects with the goals summarized as follows: 1] Epidemiology Project (Project 1): the goal is to investigate the residual malaria transmission to develop and evaluate optimal control strategies at study sites in Mali, representing different eco-zones across West Africa, 2]Malaria immuno-genetics Project (Project 2): The goal of this project is to study factors associated with gametocytogenesis in symptomatic and asymptomatic disease and their contributions to transmission in low transmission season setting (parasite and human genetics, immune response, and transmissibility) in relation with malaria control interventions in Mali, 3] Malaria vector and transmission field ecology project (Project 3): will characterize low residual transmission studying malaria vector populations and ecology in the continuum rural-urban and peri-urban setting of Bamako, Mali. These projects link the different aspects of malaria transmission and disease into a unified whole, adding the ability to distinguish the contributions of different malaria control interventions on parasite population and range of immune responses (Project 2, Immunopathogenesis) and seasonal and geographical distribution of anopheline mosquitoes vectors (Project 3). Understanding the factors relating entomological with epidemiological transmission patterns will provide more appropriate guidelines for malaria control tailored to different ecological settings in Mali and West Africa.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $631,854 )
2025	2025	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO (USTTB)	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	002	9	6/5/2025	NON-COMPETING CONTINUATION	$631,854
2025	2024	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO (USTTB)	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	001	8	4/10/2025	COMPETING CONTINUATION	$81,089
2025	2023	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO (USTTB)	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	7	4/10/2025	NON-COMPETING CONTINUATION	-$81,089
														Subtotal = $631,854

Issue Date FY: 2024 ( Subtotal = $631,854 )
2024	2024	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO (USTTB)	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	8	5/20/2024	COMPETING CONTINUATION	$631,854
														Subtotal = $631,854

Issue Date FY: 2023 ( Subtotal = $432,400 )
2023	2023	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	002	7	4/6/2023	NON-COMPETING CONTINUATION	$0
2023	2023	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	001	7	3/21/2023	NON-COMPETING CONTINUATION	$432,400
2023	2022	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	6	3/21/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $432,400

Issue Date FY: 2022 ( Subtotal = $432,400 )
2022	2022	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	6	3/11/2022	NON-COMPETING CONTINUATION	$432,400
2022	2022	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	001	6	7/28/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $432,400

Issue Date FY: 2021 ( Subtotal = $1,381,784 )
2021	2021	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	002	5	8/13/2021	NON-COMPETING CONTINUATION	$0
2021	2021	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	5	3/31/2021	NON-COMPETING CONTINUATION	$432,400
2021	2021	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	001	5	6/1/2021	NON-COMPETING CONTINUATION	$949,384
														Subtotal = $1,381,784

Issue Date FY: 2020 ( Subtotal = $885,210 )
2020	2020	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	4	3/26/2020	NON-COMPETING CONTINUATION	$885,210
														Subtotal = $885,210

Issue Date FY: 2019 ( Subtotal = $1,431,372 )
2019	2019	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	001	3	4/12/2019	SUPPLEMENT FOR EXPANSION	$458,810
2019	2019	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	002	3	6/27/2019	NON-COMPETING CONTINUATION	$525,690
2019	2019	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	3	3/12/2019	NON-COMPETING CONTINUATION	$446,872
														Subtotal = $1,431,372

Issue Date FY: 2018 ( Subtotal = $447,012 )
2018	2018	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	2	3/20/2018	NON-COMPETING CONTINUATION	$447,012
														Subtotal = $447,012

Issue Date FY: 2017 ( Subtotal = $680,416 )
2017	2017	UNIVERSITE DES SCIENCES, DES TECHNIQUES ET DES TECHNOLOGIES DE BAMAKO USTTB	HAMDALLAYE ACI 2000	BAMAKO				MLI	Allergy and Infectious Diseases Research	000	1	4/18/2017	NEW	$680,416
														Subtotal = $680,416

Grand Total All Awards = $6,954,302

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Multidisciplinary Implementation Research for malaria control and elimination in West Africa

Award Number: U19AI129387

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/18/2017

PERIOD OF PERFORMANCE END DATE: 03/31/2029

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