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Vet-LIRN antimicrobial resistance surveillance through collection of AMR data and whole genome sequencing of isolates from Canadian provinces

Award Number: U18FD007244
ORGANIZATION: FOOD AND DRUG ADMINISTRATION
OPDIV: FDA
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)
PERIOD OF PERFORMANCE START DATE: 09/20/2020
PERIOD OF PERFORMANCE END DATE: 08/31/2030

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Vet-LIRN antimicrobial resistance surveillance through collection of AMR data and whole genome sequencing of isolates from Canadian provinces - Project Summary/Abstract As a part of the FDA Veterinary Laboratory Information Response Network (Vet-LIRN) cooperative agreement, Animal Health Laboratory (AHL) will continue supporting Vet- LIRN’s Antimicrobial Resistance-Whole Genome Sequencing (AMR-WGS) program. Through already established process we will continue with routine collection of clinical bacterial isolates in source labs, provide AMR data for all isolates collected and ship isolates quarterly to the core lab for WGS. Every month the source labs will collect 4 isolates of Escherichia coli and 4 isolates of Staphylococcus pseudintermedius from dogs as well as four Salmonella enterica isolates from any animal species. In addition, eight isolates from the other (OTH) category (Klebsiella spp., Enterobacter spp., Enterococcus spp., Pseudomonas spp., etc.) will be collected following the sampling plan provided by Vet-LIRN. Antimicrobial susceptibility data will be provided for all of these isolates. Furthermore, four Campylobacter spp. and four aquatic bacterial pathogens will be collected monthly if available. Metadata for all collected isolates as well as the susceptibility data will be provided to Vet-LIRN on a quarterly basis. To ensure harmonization of methodology and support surge capacity testing for Vet-LIRN during large-scale emergency events, AHL will continue using MiSeq to do WGS of bacterial isolate following protocols provided by Vet-LIRN. Based on Vet-LIRN quarterly selection, a subgroup of the bacterial isolates will be sequenced, and their metadata and sequence information will be submitted to the National Center for Biotechnology Information (NCBI) database for scientific community use. AHL will also continue participating in proficiency testing provided by Vet-LIRN and GenomeTrakr.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	001	6	12/16/2025	COMPETING CONTINUATION	$0
2026	2024	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	5	12/15/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $88,173 )
2025	2025	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	6	9/24/2025	COMPETING CONTINUATION	$88,173
														Subtotal = $88,173

Issue Date FY: 2024 ( Subtotal = $96,803 )
2024	2024	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	5	7/31/2024	NON-COMPETING CONTINUATION	$96,803
														Subtotal = $96,803

Issue Date FY: 2023 ( Subtotal = $100,723 )
2023	2023	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	4	8/4/2023	NON-COMPETING CONTINUATION	$100,723
														Subtotal = $100,723

Issue Date FY: 2022 ( Subtotal = $97,821 )
2022	2022	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	3	8/10/2022	NON-COMPETING CONTINUATION	$97,821
														Subtotal = $97,821

Issue Date FY: 2021 ( Subtotal = $90,130 )
2021	2021	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	001	2	9/1/2021	SUPPLEMENT FOR EXPANSION	$17,813
2021	2021	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	2	8/12/2021	NON-COMPETING CONTINUATION	$72,317
														Subtotal = $90,130

Issue Date FY: 2020 ( Subtotal = $62,823 )
2020	2020	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON	N1G 2W1		CAN	Food and Drug Administration Research	001	1	9/25/2020	NEW	$0
2020	2020	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON	N1G 2W1		CAN	Food and Drug Administration Research	000	1	9/21/2020	NEW	$62,823
														Subtotal = $62,823

Grand Total All Awards = $536,473

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Vet-LIRN antimicrobial resistance surveillance through collection of AMR data and whole genome sequencing of isolates from Canadian provinces

Award Number: U18FD007244

ORGANIZATION: FOOD AND DRUG ADMINISTRATION

OPDIV: FDA

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)

PERIOD OF PERFORMANCE START DATE: 09/20/2020

PERIOD OF PERFORMANCE END DATE: 08/31/2030

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