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Vet-LIRN antimicrobial resistance surveillance through collection of AMR data and whole genome sequencing of isolates from Canadian provinces

Award Number: U18FD007244
ORGANIZATION: FOOD AND DRUG ADMINISTRATION
OPDIV: FDA
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)

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Project Summary/Abstract As a part of the FDA Veterinary Laboratory Information Response Network (Vet-LIRN) initiative ‘to support enhanced human and animal food safety’ Animal Health Laboratory (AHL) acquired MiSeq Illumina and was tasked to established a Canadian veterinary diagnostics laboratory unit (5 source labs and 1 WGS regional lab) to support and expand Vet-LIRN's Antimicrobial Resistance-Whole Genome Sequencing (AMR-WGS) program. This unit was established in 2018 and the program ran throughout 2019 with bacterial isolates (604), metadata and antimicrobial susceptibility results collection and whole genome sequencing (WGS) of selected isolates (270). The isolate collection slowed down in the second quarter of 2020 because of COVID-19, and also one laboratory dropped out of the program due to a staffing shortage. As a result, our objectives for this multiyear project are: 1. To recruit another source laboratory for isolate, metadata and antimicrobial susceptibility results collection for 2021. 2. To continue established collaboration with other source laboratories by providing them with supplies and covering quarterly shipping expenses for isolates and data collection. 3. To continue with isolates collection at AHL. 4. To increase surge capacity and capability of AHL in order to aid Vet-LIRN AMR surveillance efforts and clinical disease investigations using harmonized methodology by: a. Using Illumina MiSeq to do WGS of bacterial isolates following protocols provided by Vet-LIRN. b. Participating in proficiency testing provided by GenomeTrakr. c. Submitting sequence information to NCBI to make them publicly available.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $100,723 )
2023	2023	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	4	8/4/2023	NON-COMPETING CONTINUATION	$100,723
														Subtotal = $100,723

Issue Date FY: 2022 ( Subtotal = $97,821 )
2022	2022	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	3	8/10/2022	NON-COMPETING CONTINUATION	$97,821
														Subtotal = $97,821

Issue Date FY: 2021 ( Subtotal = $90,130 )
2021	2021	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	001	2	9/1/2021	SUPPLEMENT FOR EXPANSION	$17,813
2021	2021	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON			CAN	Food and Drug Administration Research	000	2	8/12/2021	NON-COMPETING CONTINUATION	$72,317
														Subtotal = $90,130

Issue Date FY: 2020 ( Subtotal = $62,823 )
2020	2020	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON	N1G 2W1		CAN	Food and Drug Administration Research	001	1	9/25/2020	NEW	$0
2020	2020	UNIVERSITY OF GUELPH	50 STONE RD E	GUELPH	ON	N1G 2W1		CAN	Food and Drug Administration Research	000	1	9/21/2020	NEW	$62,823
														Subtotal = $62,823

Grand Total All Awards = $351,497

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Vet-LIRN antimicrobial resistance surveillance through collection of AMR data and whole genome sequencing of isolates from Canadian provinces

Award Number: U18FD007244

ORGANIZATION: FOOD AND DRUG ADMINISTRATION

OPDIV: FDA

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)

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