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Method validation for the analysis of cannabinoids in animal specimen and hemp-based animal feed products

Award Number: U18FD006915
ORGANIZATION: FOOD AND DRUG ADMINISTRATION
OPDIV: FDA
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)
PERIOD OF PERFORMANCE START DATE: 08/01/2020
PERIOD OF PERFORMANCE END DATE: 07/31/2025

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Method validation for the analysis of cannabinoids in animal specimen and hemp-based animal feed products - Project Summary The purpose of this application is develop and validate the analysis of cannabinoids in hemp- derived food products as well as in animal specimen. The 2014 Farm Bill legalized the cultivation and production of industrial hemp (Cannabis sativa containing < 0.3%Tetrahydrocannabinol) and the removal of industrial hemp as DEA Schedule I drug. More recently, the 2018 Farm Bill has allowed for increased interest in hemp cultivation as a novel agricultural commodity under certain provisions. Hemp plants and their by-products, are considered to have nutritional and potentially therapeutic value when used as a feed source in livestock. Many commercially available hemp oils and feed product are available on the market with little information of their cannabinoids content. In addition, there is a need to develop a cannabinoid screen in animal specimen as little is known about their distribution in cattle following oral administration and the time required for depletion in edible tissues. There is also a need to have a diagnostic test available in the toxicology laboratory as pets are regularly intoxicated with cannabis-derived products: in this case, plasma and urine would be specimen of choice to detect exposure to THC. The outcomes will include: 1) the broadening capacity of the FDA to investigate animal food or drug related concerns, 2) an Increased capacity to respond to large-scale animal food/feed emergency events, 3) the improvement in the quality and standardization of Federal and State surveillance of animal food and feed. We already have experience in quantifying cannabinoids in oil and hemp-based supplements and have started to work on developing the method in bovine plasma.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	KANSAS STATE UNIVERSITY	1601 VATTIER STREET	MANHATTAN	KS	66506	RILEY	USA	Food and Drug Administration Research	000	4	7/15/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $76,000 )
2023	2023	KANSAS STATE UNIVERSITY	1601 VATTIER STREET	MANHATTAN	KS	66506	RILEY	USA	Food and Drug Administration Research	000	4	8/4/2023	NON-COMPETING CONTINUATION	$76,000
														Subtotal = $76,000

Issue Date FY: 2022 ( Subtotal = $76,000 )
2022	2022	KANSAS STATE UNIVERSITY	2 FAIRCHILD HALL	MANHATTAN	KS	66506	RILEY	USA	Food and Drug Administration Research	000	3	7/20/2022	NON-COMPETING CONTINUATION	$76,000
														Subtotal = $76,000

Issue Date FY: 2021 ( Subtotal = $76,000 )
2021	2021	KANSAS STATE UNIVERSITY	2 FAIRCHILD HALL	MANHATTAN	KS	66506	RILEY	USA	Food and Drug Administration Research	000	2	8/12/2021	NON-COMPETING CONTINUATION	$76,000
														Subtotal = $76,000

Issue Date FY: 2020 ( Subtotal = $76,000 )
2020	2020	KANSAS STATE UNIVERSITY	2 FAIRCHILD HALL	MANHATTAN	KS	66506	RILEY	USA	Food and Drug Administration Research	000	1	7/9/2020	NEW	$76,000
														Subtotal = $76,000

Grand Total All Awards = $304,000

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Method validation for the analysis of cannabinoids in animal specimen and hemp-based animal feed products

Award Number: U18FD006915

ORGANIZATION: FOOD AND DRUG ADMINISTRATION

OPDIV: FDA

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)

PERIOD OF PERFORMANCE START DATE: 08/01/2020

PERIOD OF PERFORMANCE END DATE: 07/31/2025

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