Application Organization Name: The Trustees of Columbia University in the City of New York Address: 630 West 168th, Box 49 New York, New York 10032-3702 Project Director Name: Peter Dayan, MD, MSc Contact Numbers: Phone: (212) 342-4176 / Fax: (212) 342-4180 Email Address: email@example.com Application Category: Category 1 (Research Node) Needs to be addressed: The goal of the Pediatric Emergency Medicine Northeast, West, and South (PEM-NEWS) node of the Pediatric Emergency Care Applied Research Network (PECARN) is to continue to conduct and disseminate findings from definitive, multicenter research that will meet the need to improve the emergency care of children with illness or injury. Because serious adverse outcomes are uncommon in pediatric emergency care, single institutions are frequently unable to test hypotheses definitively. Additionally, even conclusive research evidence does not readily lead to timely, equitable practice or system change. Population Served: Children younger than 18 years of age presenting for medical care in the prehospital or emergency department setting. Proposed Services: Our specific objectives are to: initiate, develop, and obtain extramural funding for high-priority hospital and prehospital-based research of children presenting for emergency care; enroll large numbers of patients into PECARN studies; conduct research to eliminate inequities in care; maintain and expand the use of a robust research data infrastructure that facilitates the efficient conduct of research; perform implementation science research to bring evidence to the bedside; build a diverse cadre of investigators invested in multicenter research relevant to Emergency Medical Services for Children (EMSC); broadly disseminate PECARN research findings; and facilitate the incorporation of PECARN findings into clinical guidelines. To meet these objectives, we will maintain a node consisting of a research node center (RNC) at Columbia Univer
sity Irving Medical Center and three diverse, high-volume hospital emergency department affiliates (HEDAs) in New York, Texas, and Colorado. The PEM-NEWS node will continue to support an Emergency Medical Services Affiliate (EMSA) Scientific Advisor to lead the conduct of prehospital research, with two EMSAs that are associated with the Colorado HEDA. PEM-NEWS will maintain two HEDAs in the PECARN Data Registry and data linkages between the EMSAs and their HEDA. To prioritize, develop and conduct research, PEM-NEWS supports nationally recognized leaders in PEM research at each HEDA as well as HEDA research infrastructure. PEM-NEWS will continue to support the growth of a diverse group of junior investigators through direct mentorship and through PEM-NEWS and PECARN educational and research opportunities. To facilitate research on inequities in care and the promotion of a diverse research workforce, we also support a Dissemination, Equity, and Inclusion Lead. To facilitate the translation of research into bedside practice across the spectrum of emergency settings, we support a Dissemination Core Lead and leverage our vast collaborations and partnerships, leading to the incorporation of PECARN findings into educational products, influential guidelines, and clinical resources. The RNC will coordinate all activities, including those related to PEM-NEWS HEDAs and the EMSA, other nodes, the EMSC Data Center, and EMSC leadership. PEM-NEWS will obtain extramural funding, produce definitive research findings, publish scientific manuscripts, create accessible dissemination products, and deliver scientific and educational presentations relevant to PECARN and EMSC.