Abstract
The overall goal of our research is to reduce HIV-related health inequities among Latinx immigrant populations.
We propose to determine the effectiveness of Hermanos de Luna y Sol (HLS), a community-based, group
intervention delivered in Spanish, designed to reduce HIV sexual risk among Latinx immigrants who identify as
gay/bisexual men or men who have sex with men (GBMSM). The study is designed as a quasi-experimental,
community control, with Oakland, CA as the intervention group and Chicago, IL as the control. Assessments
will be conducted at -3 and 0 mos., and follow-ups at 3, 6, and 12 mos. Participants (N=360; n=180 per city)
will be recruited using Time-location sampling (a venue-based sampling designed to reduce sample bias).
HLS, the intervention at the heart of this study, offers several novel features: it focuses on immigrant, Spanish-
speaking populations; it addresses racism and homophobia as factors shaping HIV risk; and uses a
community-based approach centered on community involvement (e.g., civic participation, volunteering) as a
means to foster sexual health and community building.
The study will help identify effective interventions to prevent HIV among Latinx immigrant GBMSM, a
marginalized population for which HIV preventive interventions are severely lacking. This study capitalizes on
an existing intervention designed for Spanish speaking populations; is the first of its kind to rigorously test the
intervention’s effectiveness among Latinx immigrant GBMSM using a community control design. The study
applies the best possible scientific approach to obtain estimates of intervention effectiveness. If successful, the
intervention would be relatively easy to disseminate via community organizations and the Centers for Disease
Control and Prevention. Ultimately, the study will help move forward efforts to reduce racial/ethnic health
inequities, one of the nation’s major public health priorities.
This proposal is directly relevant to the RFA on Transformative Research to Address Health Disparities and
Advance Health Equity at Minority serving Institutions. The project is led by SFSU – a Hispanic Serving
Institution-- in collaboration with two Latinx community-based organizations: La Familia and Chicago Queer
Latinx Collaborative. We are a multidisciplinary research team with the depth and breadth of experience on
HIV prevention with Latinx and GBMSM communities to successfully conduct the study. All senior personnel
are of Latin American descent, fully bilingual (Spanish and English), and three of them are women. The
proposed study is strongly aligned with NIH UNITED Initiative of fostering racial equity and inclusion in
biomedical research and is responsive to priority areas of multiple NIH institutes and centers, such NIMHD,
NIMH, and the Office of AIDS Research.