Tuesday, November 4, 2025 11/4/2025

Rutgers Optimizes Innovation (ROI) Program

Award Number: U01HL150852
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/23/2019
PERIOD OF PERFORMANCE END DATE: 08/31/2024

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Rutgers Optimizes Innovation (ROI) Program - Project Summary/Abstract The Rutgers Optimizes Innovation (ROI) Program will provide a vertically integrated mechanism to swiftly uncover promising biomedical product discoveries, and seamlessly guide the innovator through the commercialization process with financial and regulatory, IP protection, mentoring, management, and educational resources. Drawing on the biomedical/bioengineering sciences across Rutgers and on the solid expertise of the Office of Research Commercialization (ORC), we will integrate our strengths to uncover, develop and commercialize discoveries that improve health and well-being, and train the next generation of innovators. The ROI Program comprises a cooperative of Rutgers University and affiliates that includes the schools of engineering, arts and sciences, schools of medicine, nursing, dental science, public health, and research institutes and centers, industries, incubators, funders and policymakers. All entities provide significant resources to the ROI Program and have contributed to the planning, development, and leadership composition of the cooperative. Based in one of the most productive states with respect to commercialization of health-related discoveries (assets), the ROI Program will serve as a platform for translating biomedical discoveries into marketable products. Our REACH Hub will identify innovative health-related technologies by using the expertise of the NCI-funded Cancer Institute of NJ (CINJ), the Rutgers Institute for Translational Medicine and Science (RITMS, lead of the NCATS-funded CTSA) and the Biomaterials Center, funded by NSF and DOD. These technologies will be evaluated for commercialization feasibility, especially with respect to providing precision therapy to tackle an unmet need created by the heterogeneity of disease pathogenesis and response to treatment. Addressing such unmet needs will provide assets tailored to patients’ therapeutic responses that ultimately improves population health. The ROI Program will provide a streamlined and harmonized infrastructure that will enhance commercialization of academic discovery. The educational programs embedded in the ROI Program will provide our innovators with hands-on, practical training in product development and start-up requirements, while also training a diverse workforce in biomedical innovation by leveraging, coalescing and repurposing current resources, including I- Corps and iJOBS. Implementing a unique project management and mentoring program comprised of industry, disease-state and content experts will also enhance innovators’ opportunity for success. Embracing a Fail Fast Philosophy assures the technology will be developed in a cost-effective and market-conscious manner. Across all Aims, the ROI Program will collaborate with the REACH Consortium to build on their advances in platforms for commercialization, technology review, and training, and provide the Consortium with our expertise and commitment to serve as an active participating member. Importantly, evaluation milestones and metrics are planned in all aspects of the ROI Program to assure continuous quality assessment, improvement and sustainability.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$198,700 )
2025	2022	RUTGERS THE STATE UNIVERSITY OF NEW JERSEY	65 BERGEN ST	NEWARK	NJ	07107	ESSEX	USA	Trans-NIH Research Support	002	4	7/24/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$163,870
2025	2021	RUTGERS, THE STATE UNIVERSITY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	000	2	10/27/2024	SUPPLEMENT FOR EXPANSION	-$34,830
2025	2021	RUTGERS, THE STATE UNIVERSITY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	001	3	7/15/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = -$198,700

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2022	RUTGERS THE STATE UNIVERSITY OF NEW JERSEY	65 BERGEN ST	NEWARK	NJ	07107	ESSEX	USA	Trans-NIH Research Support	000	4	6/22/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	65 BERGEN ST	NEWARK	NJ	07107	ESSEX	USA	Trans-NIH Research Support	001	4	2/10/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2023	2022	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	65 BERGEN ST	NEWARK	NJ	07107	ESSEX	USA	Trans-NIH Research Support	005	4	8/25/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2023	2022	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	65 BERGEN ST	NEWARK	NJ	07107	ESSEX	USA	Trans-NIH Research Support	004	4	3/29/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1,317,442
2023	2021	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	000	2	11/21/2022	SUPPLEMENT FOR EXPANSION	$0
2023	2021	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	003	3	3/29/2023	NON-COMPETING CONTINUATION	-$999,999
2023	2020	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	002	2	3/29/2023	NON-COMPETING CONTINUATION	-$317,443
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $999,999 )
2022	2022	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	65 BERGEN ST	NEWARK	NJ	07107	ESSEX	USA	Trans-NIH Research Support	003	4	8/18/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$999,999
2022	2021	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	002	3	8/18/2022	NON-COMPETING CONTINUATION	$0
2022	2021	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	001	3	4/26/2022	NON-COMPETING CONTINUATION	$0
2022	2021	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	000	2	11/3/2021	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $999,999

Issue Date FY: 2021 ( Subtotal = $1,443,599 )
2021	2021	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	002	3	8/25/2021	NON-COMPETING CONTINUATION	$999,999
2021	2021	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	000	2	12/19/2020	SUPPLEMENT FOR EXPANSION	$443,600
2021	2020	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	001	2	4/24/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $1,443,599

Issue Date FY: 2020 ( Subtotal = $999,999 )
2020	2020	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	006	2	9/2/2020	NON-COMPETING CONTINUATION	$0
2020	2020	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	003	2	8/17/2020	NON-COMPETING CONTINUATION	$999,999
2020	2020	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	004	2	8/22/2020	NON-COMPETING CONTINUATION	$0
2020	2019	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	000	1	11/9/2019	NEW	$0
2020	2019	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	001	1	2/21/2020	NEW	$0
2020	2019	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	005	1	9/2/2020	NEW	$0
2020	2019	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	002	1	8/17/2020	NEW	$0
														Subtotal = $999,999

Issue Date FY: 2019 ( Subtotal = $999,999 )
2019	2019	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	83 SOMERSET ST	NEW BRUNSWICK	NJ	08901	MIDDLESEX	USA	Trans-NIH Research Support	000	1	9/21/2019	NEW	$999,999
														Subtotal = $999,999

Grand Total All Awards = $4,244,896

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Rutgers Optimizes Innovation (ROI) Program

Award Number: U01HL150852

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/23/2019

PERIOD OF PERFORMANCE END DATE: 08/31/2024

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