Tuesday, August 19, 2025 8/19/2025

African Neurobiobank for Precision Stroke Medicine - (ELSI) Project

Award Number: U01HG010273
ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE
OPDIV: NIH
AWARD CLASS: COOPERATIVE AGREEMENT
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/11/2022
PERIOD OF PERFORMANCE END DATE: 06/30/2023

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African Neurobiobank for Precision Stroke Medicine - (ELSI) Project - African Neurobiobank for Precision Stroke Medicine: ELSI Project: Project Summary Africa had, hitherto, been under-represented in the biobanking revolution. However, with the Human, Heredity and Health in Africa (H3Africa) initiative, biorepository science has been bolstered and biobanking - related activities are growing on the continent. In Sub - Saharan Africa (SSA), stroke incidence rates are rising, outcomes are worse, and relatively younger people are affected compared to Caucasian populations. Developing trans-omics approaches to predict, prevent, diagnose and treat stroke in the framework of current emphasis on precision/personalized medicine requires a clear understanding of the interplay of environmental and genomic risk factors. However, the ethical, legal, and social implications (ELSI) of the emerging neurobiobank and data resources are unclear in an emerging African scientific landscape with unique cultural, linguistic, and belief systems operating in a global ‘open science’ research community that increasingly supports the principles of trust, openness, storage, sharing and secondary use of biological materials. The overarching goal of the African Neurobiobank for Precision Stroke Medicine - Ethical, Legal, and Social Implications (ELSI) Project is to identify, examine and develop novel approaches to address ELSI issues of stroke biobanking in SSA. We intend to use a community-based participatory mixed methods research (CBPR) approach involving the various levels of the social ecological model to develop novel, context- relevant and culture-appropriate interventions. We have identified and examined relevant stroke biobanking ELSI issues and are developing contextual intervention tools, platforms and practices to enhance community understanding and participation in stroke biobanking activities in a way that will facilitate enduring trust, equitable and fair utilization of biobanking resources for genetic and trans-omics research. The huge potential for neuro-biobanking in Africa to advance precision medicine applicable to stroke and other neurological disorders requires that important ELSI challenges be addressed while building sustainable research and regulatory capacity, careers and infrastructure in trans-omics and biobanking science


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$69,469 )
2025	2022	COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN	UNIVERSITY COLLEGE HOSPITAL	IBADAN				NGA	Human Genome Research	000	4	11/21/2024	SUPPLEMENT FOR EXPANSION	-$69,469
														Subtotal = -$69,469

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2021	COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN	UNIVERSITY COLLEGE HOSPITAL	IBADAN				NGA	Trans-NIH Research Support	000	4	6/5/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $99,469 )
2022	2022	COLLEGE OF MEDICINE ,UNIVERSITY OF IBADAN	UNIVERSITY COLLEGE HOSPITAL	IBADAN				NGA	Human Genome Research	001	4	9/15/2022	SUPPLEMENT FOR EXPANSION	$99,469
2022	2021	COLLEGE OF MEDICINE ,UNIVERSITY OF IBADAN	UNIVERSITY COLLEGE HOSPITAL	IBADAN				NGA	Trans-NIH Research Support	000	4	9/15/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $99,469

Issue Date FY: 2021 ( Subtotal = $100,267 )
2021	2021	COLLEGE OF MEDICINE ,UNIVERSITY OF IBADAN	UNIVERSITY COLLEGE HOSPITAL	IBADAN				NGA	Trans-NIH Research Support	001	4	8/11/2021	NON-COMPETING CONTINUATION	$100,267
2021	2020	COLLEGE OF MEDICINE ,UNIVERSITY OF IBADAN	UNIVERSITY COLLEGE HOSPITAL	IBADAN				NGA	Trans-NIH Research Support	000	3	3/25/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $100,267

Issue Date FY: 2020 ( Subtotal = $105,648 )
2020	2020	COLLEGE OF MEDICINE ,UNIVERSITY OF IBADAN	UNIVERSITY COLLEGE HOSPITAL	IBADAN		200212		NGA	Trans-NIH Research Support	000	3	6/17/2020	NON-COMPETING CONTINUATION	$105,648
														Subtotal = $105,648

Issue Date FY: 2019 ( Subtotal = $105,871 )
2019	2019	COLLEGE OF MEDICINE ,UNIVERSITY OF IBADAN	UNIVERSITY COLLEGE HOSPITAL	IBADAN		200212		NGA	Human Genome Research	000	2	6/20/2019	NON-COMPETING CONTINUATION	$105,871
														Subtotal = $105,871

Issue Date FY: 2018 ( Subtotal = $100,802 )
2018	2018	COLLEGE OF MEDICINE	UNIVERSITY COLLEGE HOSPITAL	IBADAN OYO STATE				NGA	Human Genome Research	000	1	9/21/2018	NEW	$100,802
														Subtotal = $100,802

Grand Total All Awards = $442,588

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African Neurobiobank for Precision Stroke Medicine - (ELSI) Project

Award Number: U01HG010273

ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE

OPDIV: NIH

AWARD CLASS: COOPERATIVE AGREEMENT

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/11/2022

PERIOD OF PERFORMANCE END DATE: 06/30/2023

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